Author

Emanuele Valli

Observed names: E. Valli, VALLI, EMANUELE, Valli, Emanuele <1983>

Institutions: UNSW Sydney, European Institute of Oncology

Observed institutions: Boston Children's Hospital, Beth Israel Deaconess Medical Center, Harvard University, German Cancer Research Center, University of Cologne, UNSW Sydney, Yale University, University of Chicago, Fred Hutch Cancer Center, Children's Cancer Institute Australia, Dana-Farber/Harvard Cancer Center, École Polytechnique Fédérale de Lausanne, European Institute of Oncology, University of Bologna

ORCID: 0000-0002-0928-8624

Observed ORCID: 0000-0002-0928-8624

OpenAlex ID: A5067013871

Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion

2020 · Florida Voli, Emanuele Valli, et al. · Cancer Research · 436

Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma

2019 · Laura D. Gamble, Stefania Purgato, et al. · Science Translational Medicine · 160

SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability

2011 · Glenn M. Marshall, Pei Y. Liu, et al. · PLoS Genetics · 153

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ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux

2011 · Michelle J. Henderson, Michelle Haber, et al. · JNCI Journal of the National Cancer Institute · 127

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APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome

2011 · Stefania Trazzi, Valentina Maria Mitrugno, et al. · Human Molecular Genetics · 115

Direct and Coordinate Regulation of ATP-binding Cassette Transporter Genes by Myc Factors Generates Specific Transcription Signatures That Significantly Affect the Chemoresistance Phenotype of Cancer Cells

2010 · Antonio Porro, Michelle Haber, et al. · Journal of Biological Chemistry · 113

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HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder

2016 · Stefania Trazzi, Claudia Fuchs, et al. · Human Molecular Genetics · 106

A SP1/MIZ1/MYCN Repression Complex Recruits HDAC1 at theTRKAandp75NTRPromoters and Affects Neuroblastoma Malignancy by Inhibiting the Cell Response to NGF

2010 · Nunzio Iraci, Daniel Diolaiti, et al. · Cancer Research · 101

Physical Interaction between MYCN Oncogene and Polycomb Repressive Complex 2 (PRC2) in Neuroblastoma

2013 · Daisy Corvetta, Olesya Chayka, et al. · Journal of Biological Chemistry · 92

IKAROS Deletions Dictate a Unique Gene Expression Signature in Patients with Adult B-Cell Acute Lymphoblastic Leukemia

2012 · Ilaria Iacobucci, Nunzio Iraci, et al. · PLoS ONE · 92

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Combining Carbon Nanotubes and Chitosan for the Vectorization of Methotrexate to Lung Cancer Cells

2019 · Giuseppe Cirillo, Orazio Vittorio, et al. · Materials · 83

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The DMD Locus Harbours Multiple Long Non-Coding RNAs Which Orchestrate and Control Transcription of Muscle Dystrophin mRNA Isoforms

2012 · Matteo Bovolenta, Daniela Erriquez, et al. · PLoS ONE · 61

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Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition

2020 · Aaminah Khan, Emanuele Valli, et al. · Oncogene · 58

CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells

2012 · Emanuele Valli, Stefania Trazzi, et al. · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · 52

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Interplay between MycN and c-Myc regulates radioresistance and cancer stem cell phenotype in neuroblastoma upon glutamine deprivation

2020 · Marion Le Grand, Anna Mukha, et al. · Theranostics · 48

c-MYC Oncoprotein Dictates Transcriptional Profiles of ATP-Binding Cassette Transporter Genes in Chronic Myelogenous Leukemia CD34+ Hematopoietic Progenitor Cells

2011 · Antonio Porro, Nunzio Iraci, et al. · Molecular Cancer Research · 48

The Amyloid Precursor Protein (APP) Triplicated Gene Impairs Neuronal Precursor Differentiation and Neurite Development through Two Different Domains in the Ts65Dn Mouse Model for Down Syndrome

2013 · Stefania Trazzi, Claudia Fuchs, et al. · Journal of Biological Chemistry · 46

MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin

2013 · Samuele Gherardi, Emanuele Valli, et al. · Frontiers in Oncology · 45

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Magnetic Graphene Oxide Nanocarrier for Targeted Delivery of Cisplatin: A Perspective for Glioblastoma Treatment

2019 · Sami A. Makharza, Giuseppe Cirillo, et al. · Pharmaceuticals · 43

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MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4

2016 · Chengyuan Xue, Denise M.T. Yu, et al. · Oncotarget · 37

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Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer

2024 · Alice Cortesi, Francesco Gandolfi, et al. · Science Advances · 29

Chitosan–Quercetin Bioconjugate as Multi‐Functional Component of Antioxidants and Dual‐Responsive Hydrogel Networks

2019 · Giuseppe Cirillo, Manuela Curcio, et al. · Macromolecular Materials and Engineering · 29

Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo

2017 · Jayne Murray, Emanuele Valli, et al. · European Journal of Cancer · 29

Functionalized Carbon Nanostructures Versus Drug Resistance: Promising Scenarios in Cancer Treatment

2020 · Manuela Curcio, Annafranca Farfalla, et al. · Molecules · 24

Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma

2024 · Jourdin R. C. Rouaen, Antonietta Salerno, et al. · Nature Communications · 23

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Works count: 70

Citation count: 2,266

H-index: 24

I10-index: 31