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Chun Jye Lim

The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCP E3 Ligase
2010 · Chen-Ying Liu, Zheng-Yu Zha, et al. · Journal of Biological Chemistry · 542
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A Role for TAZ in Migration, Invasion, and Tumorigenesis of Breast Cancer Cells
2008 · Siew Wee Chan, Chun Jye Lim, et al. · Cancer Research · 494
Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma
2015 · Marta Garnelo, Alex Tan, et al. · Gut · 463
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Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin
2011 · Siew Wee Chan, Chun Jye Lim, et al. · Journal of Biological Chemistry · 397
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Multidimensional analyses reveal distinct immune microenvironment in hepatitis B virus-related hepatocellular carcinoma
2018 · Chun Jye Lim, Yun Hua Lee, et al. · Gut · 368
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Structural basis of YAP recognition by TEAD4 in the Hippo pathway
2010 · Liming Chen, Siew Wee Chan, et al. · Genes & Development · 256
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Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses
2017 · Valerie Chew, Liyun Lai, et al. · Proceedings of the National Academy of Sciences · 247
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TEADs Mediate Nuclear Retention of TAZ to Promote Oncogenic Transformation
2009 · Siew Wee Chan, Chun Jye Lim, et al. · Journal of Biological Chemistry · 245
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Immune activation underlies a sustained clinical response to Yttrium-90 radioembolisation in hepatocellular carcinoma
2018 · Valerie Chew, Yun Hua Lee, et al. · Gut · 243
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The hippo pathway in biological control and cancer development
2010 · Siew Wee Chan, Chun Jye Lim, et al. · Journal of Cellular Physiology · 167
Hypoxia‐driven immunosuppression by Treg and type‐2 conventional dendritic cells in HCC
2022 · Sheena Suthen, Chun Jye Lim, et al. · Hepatology · 162
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Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
2015 · Youjun Li, Hao Zhou, et al. · Cell Research · 145
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Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma
2021 · Phuong H. D. Nguyen, Siming Ma, et al. · Nature Communications · 142
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Uncoupling immune trajectories of response and adverse events from anti-PD-1 immunotherapy in hepatocellular carcinoma
2022 · Samuel Chuah, Joycelyn Lee, et al. · Journal of Hepatology · 125
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Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex
2017 · Hung Yi Kristal Kaan, Siew Wee Chan, et al. · Scientific Reports · 118
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WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ
2010 · S W Chan, C J Lim, et al. · Oncogene · 104
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Actin-binding and Cell Proliferation Activities of Angiomotin Family Members Are Regulated by Hippo Pathway-mediated Phosphorylation
2013 · Siew Wee Chan, Chun Jye Lim, et al. · Journal of Biological Chemistry · 103
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An automated staining protocol for seven-colour immunofluorescence of human tissue sections for diagnostic and prognostic use
2018 · Jeffrey Chun Tatt Lim, Joe Poh Sheng Yeong, et al. · Pathology · 90
Immunological Hallmarks for Clinical Response to BCG in Bladder Cancer
2021 · Chun Jye Lim, Phuong Hoang Diem Nguyen, et al. · Frontiers in Immunology · 66
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Expression of CD38 on Macrophages Predicts Improved Prognosis in Hepatocellular Carcinoma
2019 · Jian Hang Lam, Harry Ho Man Ng, et al. · Frontiers in Immunology · 66
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Trajectory of immune evasion and cancer progression in hepatocellular carcinoma
2022 · Phuong H. D. Nguyen, Martin Wasser, et al. · Nature Communications · 60
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IFNγ−IL-17+ CD8 T cells contribute to immunosuppression and tumor progression in human hepatocellular carcinoma
2022 · Yun Hua Lee, Samuel Chuah, et al. · Cancer Letters · 40
Immunohistochemical scoring of LAG-3 in conjunction with CD8 in the tumor microenvironment predicts response to immunotherapy in hepatocellular carcinoma
2023 · Chun Chau Lawrence Cheung, Yong Hock Justin Seah, et al. · Frontiers in Immunology · 24
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CD38 marks the exhausted CD8+ tissue-resident memory T cells in hepatocellular carcinoma
2023 · Marie J. Y. Reolo, Masayuki Otsuka, et al. · Frontiers in Immunology · 16
Author Correction: Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma
2021 · Phuong H. D. Nguyen, Siming Ma, et al. · Nature Communications · 12
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Works count: 44
Citation count: 4,713
H-index: 23
I10-index: 25
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