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Marc Siggel

AI-based structure prediction empowers integrative structural analysis of human nuclear pores
2022 · Shyamal Mosalaganti, Agnieszka Obarska-Kosinska, et al. · Science · 358
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Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex
2020 · Xudong Wu, Marc Siggel, et al. · Science · 233
Dynamic cluster formation determines viscosity and diffusion in dense protein solutions
2019 · Sören von Bülow, Marc Siggel, et al. · Proceedings of the National Academy of Sciences · 188
PyContact: Rapid, Customizable, and Visual Analysis of Noncovalent Interactions in MD Simulations
2018 · Maximilian Scheurer, Peter Rodenkirch, et al. · Biophysical Journal · 155
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Visualizing the disordered nuclear transport machinery in situ
2023 · Miao Yu, Maziar Heidari, et al. · Nature · 135
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Variable microtubule architecture in the malaria parasite
2023 · Josie L. Ferreira, Vojtěch Pražák, et al. · Nature Communications · 66
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Membrane fusion and drug delivery with carbon nanotube porins
2021 · Nga T. Ho, Marc Siggel, et al. · Proceedings of the National Academy of Sciences · 57
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Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with in Vivo Efficacy and Analysis of their Binding Mode Based on X-ray Cocrystal Structures
2017 · Geoffrey Schwertz, Matthias C. Witschel, et al. · Journal of Medicinal Chemistry · 52
Sensing their plasma membrane curvature allows migrating cells to circumvent obstacles
2023 · Ewa Sitarska, Silvia Dias Almeida, et al. · Nature Communications · 38
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FAM134B-RHD Protein Clustering Drives Spontaneous Budding of Asymmetric Membranes
2021 · Marc Siggel, Ramachandra M. Bhaskara, et al. · The Journal of Physical Chemistry Letters · 35
PyTME (Python Template Matching Engine): A fast, flexible, and multi-purpose template matching library for cryogenic electron microscopy data
2024 · Valentin J. Maurer, Marc Siggel, et al. · SoftwareX · 28
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TriMem: A parallelized hybrid Monte Carlo software for efficient simulations of lipid membranes
2022 · Marc Siggel, Sebastian Kehl, et al. · The Journal of Chemical Physics · 22
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MDBenchmark: A toolkit to optimize the performance of molecular dynamics simulations
2020 · Michael Gecht, Marc Siggel, et al. · The Journal of Chemical Physics · 21
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Phospholipid Scramblases Remodel the Shape of Asymmetric Membranes
2019 · Marc Siggel, Ramachandra M. Bhaskara, et al. · The Journal of Physical Chemistry Letters · 21
The distance between the plasma membrane and the actomyosin cortex acts as a nanogate to control cell surface mechanics
2023 · Sergio Lembo, Léanne Strauss, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 18
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ColabSeg: An interactive tool for editing, processing, and visualizing membrane segmentations from cryo-ET data
2024 · Marc Siggel, Rasmus K. Jensen, et al. · Journal of Structural Biology · 16
What shapes template-matching performance in cryogenic electron tomography in situ?
2024 · Valentin J. Maurer, Marc Siggel, et al. · Acta Crystallographica Section D Structural Biology · 12
Tracking of Fluorescently Labeled Polymer Particles Reveals Surface Effects during Shear-Controlled Aggregation
2017 · Stefano Caimi, Alberto Cingolani, et al. · Langmuir · 10
Physics-based, data-driven cell-scale membrane simulations with HMFF
2025 · Valentin J. Maurer, Marc Siggel, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4
The membrane-to-cortex distance regulates mDia1 activity to control cortical mechanics
2026 · Léanne Strauss, Sergio Lembo, et al. · Nature Communications
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Physics-based, data-driven cell-scale membrane simulations with HMFF
2026 · Maurer, Valentin, Siggel, Marc, et al. · Zenodo (CERN European Organization for Nuclear Research)
Supporting data for: "Sensing their plasma membrane curvature allows migrating cells to circumvent obstacles" by Ewa Sitarska, Silvia Dias Almeida, Marianne Sandvold Beckwith, Julian Stopp, Jakub Czuchnowski, Marc Siggel, Rita Roessner, Aline Tschanz, Christer Ejsing, Yannick Schwab, Jan Kosinski, Michael Sixt, Anna Kreshuk, Anna Erzberger and Alba Diz-Muñoz
2023 · Siggel, Marc · Figshare
Integrative Structural Analysis of Human Nuclear Pore Complex
2022 · Shyamal Mosalaganti, Agnieszka Obarska-Kosinska, et al. · Microscopy and Microanalysis
MDBenchmark: A Toolkit to Optimize the Performance of Molecular Dynamics Simulations
2020 · Michael Gecht, Marc Siggel, et al. · ChemRxiv
CCDC 1515139: Experimental Crystal Structure Determination
2017 · Schwertz, Geoffrey, Witschel, Matthias C., et al. · The Cambridge Structural Database
Works count: 30
Citation count: 1,469
H-index: 16
I10-index: 18
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