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Yaozong Chen
Observed names:
Chen, Yaozong,
Y. Chen,
Y.Z. Chen
Institution:
Uniformed Services University of the Health Sciences
Observed institutions:
National Institutes of Health,
Uniformed Services University of the Health Sciences,
Sun Yat-sen University,
Hong Kong University of Science and Technology,
National Cancer Institute,
Center for Cancer Research
show all 6
ORCID:
0000-0001-5380-2339
Observed ORCID:
0000-0001-5380-2339
OpenAlex ID:
A5067232105
Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy
2021
·
Irfan Ullah
, Jérémie Prévost
, et al.
·
Immunity
·
215
PDF
Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern
2021
·
Wenwei Li
, Yaozong Chen
, et al.
·
Cell Reports
·
132
Bile salt hydrolase in non-enterotoxigenic Bacteroides potentiates colorectal cancer
2023
·
Lulu Sun
, Yi Zhang
, et al.
·
Nature Communications
·
120
PDF
A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection
2022
·
Guillaume Beaudoin-Bussières
, Yaozong Chen
, et al.
·
Cell Reports
·
117
PDF
Structure and inhibition of SARS-CoV-2 spike refolding in membranes
2024
·
Michael W. Grunst
, Zhuan Qin
, et al.
·
Science
·
55
PDF
Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities
2022
·
Yaozong Chen
, Lulu Sun
, et al.
·
Science Advances
·
48
Requirement of the Cep57-Cep63 Interaction for Proper Cep152 Recruitment and Centriole Duplication
2020
·
Zhuang Wei
, Tae-Sung Kim
, et al.
·
Molecular and Cellular Biology
·
35
Highly emissive and biocompatible dopamine-derived oligomers as fluorescent probes for chemical detection and targeted bioimaging
2014
·
Bin Xiong
, Yin Chen
, et al.
·
Chemical Communications
·
34
Interaction of Human ACE2 to Membrane-Bound SARS-CoV-1 and SARS-CoV-2 S Glycoproteins
2020
·
Sai Priya Anand
, Yaozong Chen
, et al.
·
Viruses
·
31
PDF
HIV-1 Vpu restricts Fc-mediated effector functions in vivo
2022
·
Jérémie Prévost
, Sai Priya Anand
, et al.
·
Cell Reports
·
26
Nebulized delivery of a broadly neutralizing SARS-CoV-2 RBD-specific nanobody prevents clinical, virological, and pathological disease in a Syrian hamster model of COVID-19
2022
·
Thomas J. Esparza
, Yaozong Chen
, et al.
·
mAbs
·
22
An Atypical α/β-Hydrolase Fold Revealed in the Crystal Structure of Pimeloyl-Acyl Carrier Protein Methyl Esterase BioG from Haemophilus influenzae
2016
·
Jie Shi
, Xinyun Cao
, et al.
·
Biochemistry
·
22
Benzyl benzoates: New phlorizin analogs as mushroom tyrosinase inhibitors
2010
·
Yuntai Fang
, Yaozong Chen
, et al.
·
Bioorganic & Medicinal Chemistry
·
20
VE607 stabilizes SARS-CoV-2 Spike in the “RBD-up” conformation and inhibits viral entry
2022
·
Shilei Ding
, Irfan Ullah
, et al.
·
iScience
·
17
PDF
A Thiamine-Dependent Enzyme Utilizes an Active Tetrahedral Intermediate in Vitamin K Biosynthesis
2016
·
Haigang Song
, Chen Dong
, et al.
·
Journal of the American Chemical Society
·
17
Structural Basis for the ATP-dependent Configuration of Adenylation Active Site in Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase
2015
·
Yaozong Chen
, Yueru Sun
, et al.
·
Journal of Biological Chemistry
·
17
Temperature Influences the Interaction between SARS-CoV-2 Spike from Omicron Subvariants and Human ACE2
2022
·
Shang Yu Gong
, Shilei Ding
, et al.
·
Viruses
·
16
PDF
Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir
2023
·
Jérémie Prévost
, Yaozong Chen
, et al.
·
Nature Communications
·
13
PDF
An anti-SARS-CoV-2 non-neutralizing antibody with Fc-effector function defines a new NTD epitope and delays neuroinvasion and death in K18-hACE2 mice
2021
·
Guillaume Beaudoin-Bussières
, Yaozong Chen
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
11
PDF
Two active site arginines are critical determinants of substrate binding and catalysis in MenD: a thiamine-dependent enzyme in menaquinone biosynthesis
2018
·
Mingming Qin
, Haigang Song
, et al.
·
Biochemical Journal
·
11
Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD
2022
·
Yaozong Chen
, Jérémie Prévost
, et al.
·
iScience
·
10
Live Imaging of SARS-CoV-2 Infection in Mice Reveals Neutralizing Antibodies Require Fc Function for Optimal Efficacy
2021
·
Irfan Ullah
, Jérémie Prévost
, et al.
·
SSRN Electronic Journal
·
8
Crystal structure of the thioesterification conformation of Bacillus subtilis o-succinylbenzoyl-CoA synthetase reveals a distinct substrate-binding mode
2017
·
Yaozong Chen
, Tin Lok Li
, et al.
·
Journal of Biological Chemistry
·
8
PDF
Mechanistic Insights from the Crystal Structure of Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase Complexed with the Adenylate Intermediate
2016
·
Yaozong Chen
, Yiping Jiang
, et al.
·
Biochemistry
·
8
The molecular basis of the neutralization breadth of the RBD-specific antibody CoV11
2023
·
William D. Tolbert
, Yaozong Chen
, et al.
·
Frontiers in Immunology
·
5
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Works count:
59
Citation count:
1,020
H-index:
16
I10-index:
21
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