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Author

Wilman Luk

Observed names: W Luk, Wil Luk
ORCID: 0000-0003-2627-4547
Observed ORCID: 0000-0003-2627-4547
OpenAlex ID: A5067272210
Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target
2011 · Y. Joy Yu, Yin Zhang, et al. · Science Translational Medicine · 802
Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates
2014 · Y. Joy Yu, Jasvinder K. Atwal, et al. · Science Translational Medicine · 373
Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants
2014 · Nga Bien-Ly, Y. Joy Yu, et al. · The Journal of Experimental Medicine · 356
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Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies
2015 · Y. Joy Yu Zuchero, Xiaocheng Chen, et al. · Neuron · 286
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Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier
2013 · Jessica A. Couch, Y. Joy Yu, et al. · Science Translational Medicine · 278
A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-β Production in Vivo
2011 · Jasvinder K. Atwal, Yongmei Chen, et al. · Science Translational Medicine · 276
Lack of Widespread BBB Disruption in Alzheimer’s Disease Models: Focus on Therapeutic Antibodies
2015 · Nga Bien-Ly, C. Andrew Boswell, et al. · Neuron · 196
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Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer’s disease
2021 · Gai Ayalon, Seung-Hye Lee, et al. · Science Translational Medicine · 112
PILRα Negatively Regulates Mouse Inflammatory Arthritis
2014 · Yonglian Sun, Patrick Caplazi, et al. · The Journal of Immunology · 41
Prospective Design of Anti‐Transferrin Receptor Bispecific Antibodies for Optimal Delivery into the Human Brain
2016 · JS Kanodia, K Gadkar, et al. · CPT Pharmacometrics & Systems Pharmacology · 34
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Characterization of A Sensitive Mouse Aβ40 Pd Biomarker Assay for Alzheimer’s Disease Drug Development in Wild-Type Mice
2016 · Yanmei Lu, Kwame Hoyte, et al. · Bioanalysis · 13
Multi-modal analyses of proteomic measurements associated with type 2 diabetes from the Project Baseline Health Study
2025 · Alessandra Breschi, Yuliang Wang, et al. · Communications Medicine · 1
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Prognostic Biomarker Signature of Relapse in Neuromyelitis Optica Spectrum Disorders in the CIRCLES Observational Study
2026 · Elea Bach, Alessandra Breschi, et al. · Neurology Neuroimmunology & Neuroinflammation
P2–399: Modest reductions in BACE1 activity significantly reduce beta‐amyloid plaque load and neuroinflammation in a mouse model of Alzheimer's disease
2013 · William Meilandt, Jasvinder Atwal, et al. · Alzheimer s & Dementia
P1‐249: Role of BACE1 and BACE2 in the production of endogenous mouse Aß
2012 · William Meilandt, Jasvinder Atwal, et al. · Alzheimer s & Dementia
Abstract LB-126: A pooled shRNA screen for erlotinib sensitizers in Kras-mutant non-small cell lung cancer
2010 · Shaun Cordes, Nick Dompe, et al. · Cancer Research
Works count: 16
Citation count: 2,768
H-index: 11
I10-index: 11
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