Get started
Author

Tooru M. Mizuno

Observed names: T M Mizuno, T MIZUNO, T Mizuno, T. M. Mizuno, T. Mizuno, TM Mizuno, Tooru M Mizuno, Tooru Mizuno
Observed institutions: United States Department of Veterans Affairs, Veterans Health Administration, Kyoto Prefectural University of Medicine, James J. Peters VA Medical Center, Sakamoto Mental Health Center, University of Manitoba, Niigata University, Yokohama City University, Icahn School of Medicine at Mount Sinai
ORCID: 0000-0002-0836-3506
Observed ORCID: 0000-0002-0836-3506
OpenAlex ID: A5067410332
Hypothalamic Pro-Opiomelanocortin mRNA Is Reduced By Fasting in ob/ob and db/db Mice, but Is Stimulated by Leptin
1998 · Tooru M Mizuno, Steven P Kleopoulos, et al. · Diabetes · 521
PDF
Evidence That Glucose Metabolism Regulates Leptin Secretion from Cultured Rat Adipocytes
1998 · Wendy M. Mueller, Francine M. Gregoire, et al. · Endocrinology · 434
Hypothalamic Agouti-Related Protein Messenger Ribonucleic Acid Is Inhibited by Leptin and Stimulated by Fasting
1999 · Tooru M. Mizuno, Charles V. Mobbs · Endocrinology · 400
PDF
Targeted Deletion of the Vgf Gene Indicates that the Encoded Secretory Peptide Precursor Plays a Novel Role in the Regulation of Energy Balance
1999 · Seung Hahm, Tooru M. Mizuno, et al. · Neuron · 223
PDF
Fasting Regulates Hypothalamic Neuropeptide Y, Agouti-Related Peptide, and Proopiomelanocortin in Diabetic Mice Independent of Changes in Leptin or Insulin1
1999 · Tooru M. Mizuno, Hideo Makimura, et al. · Endocrinology · 188
Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity.
1996 · T M Mizuno, H Bergen, et al. · Proceedings of the National Academy of Sciences · 152
Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake
2002 · Hideo Makimura, Tooru M Mizuno, et al. · BMC Neuroscience · 150
PDF
Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin
1998 · T. M. Mizuno, S. P. Kleopoulos, et al. · Diabetes · 142
Fat Mass and Obesity Associated (FTO) Gene and Hepatic Glucose and Lipid Metabolism
2018 · Tooru M. Mizuno · Nutrients · 135
PDF
Hyperphagia and Weight Gain after Gold-Thioglucose: Relation to Hypothalamic Neuropeptide Y and Proopiomelanocortin**This work was supported by grants from the Children’s Hospital Research Foundation (to H.T.B.) and the NIH (DK-50110; to C.V.M.).
1998 · Hugo T. Bergen, Tooru M. Mizuno, et al. · Endocrinology · 114
Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice.
2000 · H Makimura, T M Mizuno, et al. · Diabetes · 102
PDF
VGF is Required for Obesity Induced by Diet, Gold Thioglucose Treatment, and Agouti and is Differentially Regulated in Pro-Opiomelanocortin- and Neuropeptide Y-Containing Arcuate Neurons in Response to Fasting
2002 · Seung Hahm, Csaba Fekete, et al. · Journal of Neuroscience · 100
PDF
Acetylcholine release in the rat hippocampus as measured by the microdialysis method correlates with motor activity and exhibits a diurnal variation
1991 · T. Mizuno, Y. Endo, et al. · Neuroscience · 97
Resistance to diet-induced obesity is associated with increased proopiomelanocortin mRNA and decreased neuropeptide Y mRNA in the hypothalamus
1999 · Hugo T. Bergen, Tooru Mizuno, et al. · Brain Research · 96
Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression
2003 · Hideo Makimura, Tooru M Mizuno, et al. · BMC Physiology · 94
PDF
Transgenic Neuronal Expression of Proopiomelanocortin Attenuates Hyperphagic Response to Fasting and Reverses Metabolic Impairments in Leptin-Deficient Obese Mice
2003 · Tooru M. Mizuno, Kevin A. Kelley, et al. · Diabetes · 85
Cerulenin Mimics Effects of Leptin on Metabolic Rate, Food Intake, and Body Weight Independent of the Melanocortin System, but Unlike Leptin, Cerulenin Fails to Block Neuroendocrine Effects of Fasting
2001 · Hideo Makimura, Tooru M. Mizuno, et al. · Diabetes · 80
PDF
Impaired anorectic effect of leptin in neurotensin receptor 1-deficient mice
2008 · Eun Ran Kim, Arnold Leckstrom, et al. · Behavioural Brain Research · 73
Impaired glucose signaling as a cause of obesity and the metabolic syndrome: The glucoadipostatic hypothesis
2005 · C MOBBS, F ISODA, et al. · Physiology & Behavior · 73
Adiponectin is stimulated by adrenalectomy inob/obmice and is highly correlated with resistin mRNA
2002 · Hideo Makimura, Tooru M. Mizuno, et al. · American Journal of Physiology-Endocrinology and Metabolism · 73
Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome
2009 · N J Poritsanos, T M Mizuno, et al. · International Journal of Obesity · 69
Erratum: Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and in ob/ob and db/db mice, but is stimulated by leptin (Diabetes (1998) 47 (294-297))
1998 · Tooru M. Mizuno, Steven P. Kleopoulos, et al. · Diabetes · 68
Effects of Nutritional Status and Aging on Leptin Gene Expression in Mice: Importance of Glucose
1996 · T. Mizuno, H. Bergen, et al. · Hormone and Metabolic Research · 63
Age-related changes in diurnal acetylcholine release in the prefrontal cortex of male rats as measured by microdialysis
1996 · D. Mitsushima, T. Mizuno, et al. · Neuroscience · 63
Involvement of RAGE, NADPH Oxidase, and Ras/Raf-1 Pathway in Glycated LDL-Induced Expression of Heat Shock Factor-1 and Plasminogen Activator Inhibitor-1 in Vascular Endothelial Cells
2010 · Ganesh V. Sangle, Ruozhi Zhao, et al. · Endocrinology · 55
Works count: 303
Citation count: 4,658
H-index: 34
I10-index: 55
Year
Topic
Type