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Debra Odink
OpenAlex ID:
A5067525435
A novel serum glucocorticoid regulated kinase 1 inhibitor improves cardiac structure and function in heart failure
2025
·
Eric Campeau
, Sabindra Pradhananga
, et al.
·
Research Square
·
1
PDF
Genetic, Preclinical, and Clinical Evidence Supports SGK1 Inhibition in Heart Failure
2026
·
Sabindra Pradhananga
, Dinesh Srinivasan
, et al.
·
JACC Heart Failure
Abstract Wed159: A Potent Serum and Glucocorticoid-Regulated Kinase 1 (SGK1) Inhibitor is Protective in a Model of CKMD
2026
·
Eric Campeau
, Sabindra Pradhananga
, et al.
·
Circulation Research
Abstract 4369238: THRV-1268, a potent and selective serum and glucocorticoid regulated kinase (SGK1) inhibitor, improves adverse cardiac remodeling better than Jardiance® (empagliflozin), a sodium-glucose cotransporter 2 (SGLT2) inhibitor in heart failure
2025
·
Sabindra Pradhananga
, William Salvail
, et al.
·
Circulation
Abstract 4369927: The serum and glucocorticoid regulated kinase 1 (SGK1) inhibitor THRV-1268 attenuates hallmarks of heart failure by reducing inflammation and fibrosis beyond sodium/glucose cotransporter 2 inhibition
2025
·
Eric Campeau
, Sabindra Pradhananga
, et al.
·
Circulation
Abstract 4369991: Small molecule inhibitors of serum glucocorticoid kinase 1 (SGK1) prevent cardiac structural and functional decline induced in a transverse aortic constriction (TAC) model
2025
·
Dinesh Srinivasan
, Sabindra Pradhananga
, et al.
·
Circulation
Abstract 4147456: Serum and Glucocorticoid Regulated Kinase 1 (SGK1) Inhibition Induces Anti-Fibrotic and Anti-Inflammatory Responses: Relevance to Cardiac Fibrosis
2024
·
Delphine Labit
, Maroua Khalifa
, et al.
·
Circulation
Abstract P4-08-21: Development of novel inhibitors of the serum/glucocorticoid induced kinase (SGK) family to address limitations of AKT/PI3K/mTOR inhibitors in breast cancer
2023
·
Delphine Labit
, Sabindra Pradhananga
, et al.
·
Cancer Research
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