Get started
Author

Sylvester Ifeanyi Omoruyi

Observed names: Omoruyi, S.I., Omoruyi, Sylvester, S. I. Omoruyi, SI Omoruyi, Sylvester I. Omoruyi, Sylvester L. Omoruyi, Sylvester Omoruyi, SylvesterI Omoruyi, SylvesterIfeanyi Omoruyi
Observed institutions: University of Cape Town, Cape Peninsula University of Technology, University of the Witwatersrand, Stellenbosch University, University of Benin, University of the Western Cape
ORCID: 0000-0002-1119-7780
Observed ORCID: 0000-0002-1119-7780
OpenAlex ID: A5067539766
Exploitation of a novel phenothiazine derivative for its anti-cancer activities in malignant glioblastoma
2020 · S. I. Omoruyi, O. E. Ekpo, et al. · APOPTOSIS · 53
Design, synthesis and evaluation of indole derivatives as multifunctional agents against Alzheimer's disease
2018 · Ireen Denya, Sarel F. Malan, et al. · MedChemComm · 40
GRP78/BIP/HSPA5 as a Therapeutic Target in Models of Parkinson’s Disease: A Mini Review
2019 · Adaze Bijou Enogieru, Sylvester Ifeanyi Omoruyi, et al. · Advances in Pharmacological Sciences · 38
PDF
Versatility of 7-Substituted Coumarin Molecules as Antimycobacterial Agents, Neuronal Enzyme Inhibitors and Neuroprotective Agents
2017 · Erika Kapp, Hanri Visser, et al. · Molecules · 30
PDF
Long‑term consumption of fermented rooibos herbal tea offers neuroprotection against ischemic brain injury in rats
2017 · Olusiji Akinrinmade, Sylvester Omoruyi, et al. · Acta Neurobiologiae Experimentalis · 30
PDF
The potential of chalcone-capped gold nanoparticles for the management of diabetes mellitus
2021 · Akinfenwa A. Omolaja, Brendon Pearce, et al. · Surfaces and Interfaces · 27
Design, synthesis, and evaluation of 3,7-substituted coumarin derivatives as multifunctional Alzheimer’s disease agents
2021 · Sheunopa C. Mzezewa, Sylvester I. Omoruyi, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 25
PDF
Neuroprotective Activities of Crossyne flava Bulbs and Amaryllidaceae Alkaloids: Implications for Parkinson’s Disease
2021 · Sylvester I. Omoruyi, Abobaker S. Ibrakaw, et al. · Molecules · 23
PDF
Design, synthesis and evaluation of pentacycloundecane and hexacycloundecane propargylamine derivatives as multifunctional neuroprotective agents
2018 · Frank T. Zindo, Sarel F. Malan, et al. · European Journal of Medicinal Chemistry · 22
Cytotoxic activities of selected plants of the family Amaryllidaceae on brain tumour cell lines
2020 · Sylvester I. Omoruyi, Tusekile S. Kangwa, et al. · South African Journal of Botany · 19
Open and rearranged norbornane derived polycyclic cage molecules as potential neuroprotective agents through attenuation of MPP+- and calcium overload-induced excitotoxicity in neuroblastoma SH-SY5Y cells
2020 · Ayodeji O. Egunlusi, Sarel F. Malan, et al. · European Journal of Medicinal Chemistry · 17
Aqueous leaf extract of Sutherlandia frutescens attenuates ROS-induced apoptosis and loss of mitochondrial membrane potential in MPP+-treated SH-SY5Y cells
2020 · Adaze B. Enogieru, Sylvester I. Omoruyi, et al. · Tropical Journal of Pharmaceutical Research · 16
PDF
In vitro neuroprotective potential of Clivia miniata and Nerine humilis (Amaryllidaceae) in MPP+-induced neuronal toxicity in SH-SY5Y neuroblastoma cells
2020 · Sylvester I. Omoruyi, Joshua Delport, et al. · South African Journal of Botany · 15
Neuroprotective Effects of Glycyrrhiza glabra Total Extract and Isolated Compounds
2024 · Ali O. E. Eltahir, Sylvester I. Omoruyi, et al. · Pharmaceuticals · 14
PDF
Neuroprotective Activities of Boophone haemanthoides (Amaryllidaceae) Extract and Its Chemical Constituents
2020 · Abobaker S. Ibrakaw, Sylvester I. Omoruyi, et al. · Molecules · 14
PDF
Potential antiparkinsonian agents derived from South African medicinal plants
2018 · Adaze Bijou Enogieru, Sylvester Ifeanyi Omoruyi, et al. · Journal of Herbal Medicine · 14
Fractions of Hoslundia opposita Vahl and hoslundin induced apoptosis in human cancer cells via mitochondrial-dependent reactive oxygen species (ROS) generation
2022 · Abosede Christiana Ajibare, Osaretin Albert Taiwo Ebuehi, et al. · Biomedicine & Pharmacotherapy · 13
PDF
Characterization and Toxicity of Hypoxoside Capped Silver Nanoparticles
2022 · Umar M. Badeggi, Sylvester I. Omoruyi, et al. · Plants · 13
PDF
Preliminary investigation of the neuroprotective potentials of Crossyne guttata in MPP+-induced toxicity in SH-SY5Y
2019 · Sylvester I. Omoruyi, Adaze Bijou Enogieru, et al. · Journal of African Association of Physiological Sciences · 9
Extracts of Hunteria umbellata reverses the effect of streptozotocin-induced pancreatic islet-cell destruction
2014 · OghenakogieI Momodu, AB Enogieru, et al. · Journal of Experimental and Clinical Anatomy · 9
Antioxidant and apoptosis-inhibition potential of Carpobrotus edulis in a model of parkinson’s disease
2018 · Adaze Bijou Enogieru, Sylvester I. Omoruyi, et al. · Journal of African Association of Physiological Sciences · 8
An update on the bioactivities and health benefits of two plant-derived lignans, phyllanthin and hypophyllanthin
2024 · Sylvester I. Omoruyi, Joshua Delport, et al. · Oriental Pharmacy and Experimental Medicine · 7
Uvaria afzelii root extract protects the liver against damage caused by carbontetrachloride ingestion
2014 · SylvesterIfeanyi Omoruyi, MaduIfeoma Joan, et al. · Journal of Experimental and Clinical Anatomy · 6
Aspalathin and linearthin from Aspalathus linearis (Rooibos) protect SH-SY5Y cells from MPP+-induced neuronal toxicity
2023 · Sylvester I. Omoruyi, Akeem O. Akinfenwa, et al. · South African Journal of Botany · 5
Cytotoxic and apoptosis-inducing effects of Sutherlandia frutescens in neuroblastoma cells
2018 · Sylvester I. Omoruyi, Adaze Bijou Enogieru, et al. · Journal of African Association of Physiological Sciences · 5
Works count: 49
Citation count: 501
H-index: 14
I10-index: 18
Year
Topic
Type