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Stephen E. Zale

Observed names: STEPHEN E. ZALE, Stephen E Zale, Stephen Zale
OpenAlex ID: A5068065636
Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile
2012 · Jeffrey Hrkach, Daniel Von Hoff, et al. · Science Translational Medicine · 1,148
Membrane-Based Affinity Technology for Commercial Scale Purifications
1988 · Steve Brandt, Randal A. Goffe, et al. · Nature Biotechnology · 298
Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors
2016 · Daniel D. Von Hoff, Monica M. Mita, et al. · Clinical Cancer Research · 289
Why does ribonuclease irreversibly inactivate at high temperatures?
1986 · Stephen E. Zale, Alexander M. Klibanov · Biochemistry · 275
Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo
2016 · Susan Ashton, Young Ho Song, et al. · Science Translational Medicine · 218
Protein Spray-Freeze Drying. Effect of Atomization Conditions on Particle Size and Stability
2000 · Henry R Costantino, Laleh Firouzabadian, et al. · Pharmaceutical Research · 186
Nanomedicines: From Bench to Bedside and Beyond
2016 · Henry Havel, Gregory Finch, et al. · The AAPS Journal · 149
Protein spray freeze drying. 2. Effect of formulation variables on particle size and stability
2002 · Henry R. Costantino, Laleh Firouzabadian, et al. · Journal of Pharmaceutical Sciences · 129
Sustained Delivery of Proteins for Novel Therapeutic Products
1998 · Raymond T. Bartus, Mark A. Tracy, et al. · Science · 108
On the role of reversible denaturation (unfolding) in the irreversible thermal inactivation of enzymes
1983 · Stephen E. Zale, Alexander M. Klibanov · Biotechnology and Bioengineering · 100
Effects of metal salts on poly(DL-lactide-co-glycolide) polymer hydrolysis
1997 · Yan Zhang, Stephen Zale, et al. · Journal of Biomedical Materials Research · 85
On firm ground: IP protection of therapeutic nanoparticles
2010 · Paul Burgess, Peter Barton Hutt, et al. · Nature Biotechnology · 84
A novel in situ hydrophobic ion pairing (HIP) formulation strategy for clinical product selection of a nanoparticle drug delivery system
2016 · Young Ho Song, Eyoung Shin, et al. · Journal of Controlled Release · 83
A Quality by Design Approach to Developing and Manufacturing Polymeric Nanoparticle Drug Products
2016 · Greg Troiano, Jim Nolan, et al. · The AAPS Journal · 75
Comprehensive study of the drug delivery properties of poly( l -lactide)-poly(ethylene glycol) nanoparticles in rats and tumor-bearing mice
2017 · Vladimir Shalgunov, Daria Zaytseva-Zotova, et al. · Journal of Controlled Release · 65
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Enzymatic synthesis of formic acid from H2 and CO2 and production of hydrogen from formic acid
1982 · Alexander M. Klibanov, Barbara N. Alberti, et al. · Biotechnology and Bioengineering · 60
111In- and IRDye800CW-Labeled PLA–PEG Nanoparticle for Imaging Prostate-Specific Membrane Antigen-Expressing Tissues
2016 · Sangeeta R. Banerjee, Catherine A. Foss, et al. · Biomacromolecules · 54
Relationship between encapsulated drug particle size and initial release of recombinant human growth hormone from biodegradable microspheres
2004 · Henry R. Costantino, Olufunmi L. Johnson, et al. · Journal of Pharmaceutical Sciences · 34
Mechanisms of Irreversible Thermoinactivation of Enzymes
1984 · STEPHEN E. ZALE, ALEXANDER M. KLIBANOV · Annals of the New York Academy of Sciences · 16
A novel long-acting formulation of oral buprenorphine/naloxone produces prolonged decreases in fentanyl self-administration by rhesus monkeys
2022 · Richard W. Foltin, Stephen Zale, et al. · Drug and Alcohol Dependence · 2
Application of immobilized hydrogenase to h2 storage in concentrated solutions of methyl viologen
1982 · Stephen E. Zale, Alexander M. Klibanov · Applied Biochemistry and Biotechnology · 2
SUN-663 Preclinical Evaluation of SYNT-101: Effects on Glycemic Control, Weight Loss, and Body Composition in DIO Rodents
2025 · Mary Ashley Hudson, Luis Sandoval, et al. · Journal of the Endocrine Society
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SUN-664 SYNT-101: First-in-Human Evaluation of a Novel Pharmacologic Therapeutic to Replicate Gastric Bypass for Management of Obesity
2025 · Mary Ashley Hudson, Luis Sandoval, et al. · Journal of the Endocrine Society
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Supplemental Section - Clean from Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors
2023 · Daniel D. Von Hoff, Monica M. Mita, et al.
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Supplemental Section - Clean from Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors
2023 · Daniel D. Von Hoff, Monica M. Mita, et al.
Works count: 30
Citation count: 3,460
H-index: 18
I10-index: 19
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