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Author

Nehal E. Elsadek

Observed name: Nehal Elsadek
ORCID: 0000-0001-7859-0280
Observed ORCID: 0000-0001-7859-0280
OpenAlex ID: A5068072448
Polyethylene glycol (PEG): The nature, immunogenicity, and role in the hypersensitivity of PEGylated products
2022 · Mohamed Ibrahim, Eslam Ramadan, et al. · Journal of Controlled Release · 496
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Anti-PEG IgM production and accelerated blood clearance phenomenon after the administration of PEGylated exosomes in mice
2021 · Sherif E. Emam, Nehal E. Elsadek, et al. · Journal of Controlled Release · 92
Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues
2019 · Sherif E. Emam, Amr Selim Abu Lila, et al. · European Journal of Pharmaceutics and Biopharmaceutics · 78
Hepatosplenic phagocytic cells indirectly contribute to anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes: Appearance of an unexplained mechanism in the ABC phenomenon
2020 · Marwa Mohamed El Sayed, Haruka Takata, et al. · Journal of Controlled Release · 56
Electrospun Nanofibers Revisited: An Update on the Emerging Applications in Nanomedicine
2022 · Nehal E. Elsadek, Abdalrazeq Nagah, et al. · Materials · 52
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Anti-PEG IgM production induced by PEGylated liposomes as a function of administration route
2023 · Haruka Takata, Taro Shimizu, et al. · Journal of Controlled Release · 47
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Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice
2020 · Nehal E. Elsadek, Amr S. Abu Lila, et al. · European Journal of Pharmaceutics and Biopharmaceutics · 44
Impact of Pre-Existing or Induced Anti-PEG IgM on the Pharmacokinetics of Peginterferon Alfa-2a (Pegasys) in Mice
2020 · Nehal E. Elsadek, Eri Hondo, et al. · Molecular Pharmaceutics · 29
Immunological responses to PEGylated proteins
2019 · Nehal E. Elsadek, Amr S. Abu Lila, et al. · Elsevier eBooks · 23
The Post-insertion Method for the Preparation of PEGylated Liposomes
2023 · Sherif E. Emam, Nehal E. Elsadek, et al. · Methods in molecular biology · 17
A mouse model for studying the effect of blood anti-PEG IgMs levels on the in vivo fate of PEGylated liposomes
2022 · Marwa M. El Sayed, Taro Shimizu, et al. · International Journal of Pharmaceutics · 16
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Pegfilgrastim (PEG-G-CSF) Induces Anti-polyethylene Glycol (PEG) IgM via a T Cell-Dependent Mechanism
2020 · Nehal E. Elsadek, Sherif E. Emam, et al. · Biological and Pharmaceutical Bulletin · 14
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Nucleic acids delivered by PEGylated cationic liposomes in systemic lupus erythematosus-prone mice: A possible exacerbation of lupus nephritis in the presence of pre-existing anti-nucleic acid antibodies
2021 · Haruka Takata, Taro Shimizu, et al. · International Journal of Pharmaceutics · 12
Complement activation-related pseudo allergy of PEGylated products: Safety aspects, models, the role of anti-PEG antibodies, and ways to overcome
2022 · Mahmoud Mohamed, Nehal Elsadek, et al. · Journal of advanced Biomedical and Pharmaceutical Sciences · 11
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Incorporating Gangliosides into PEGylated Cationic Liposomes that Complexed DNA Attenuates Anti-PEG Antibody Production but Not Anti-DNA Antibody Production in Mice
2021 · Milad Reda Qelliny, Taro Shimizu, et al. · Molecular Pharmaceutics · 9
Using Bio-Layer Interferometry to Evaluate Anti-PEG Antibody-Mediated Complement Activation
2021 · Mahmoud Mostafa, Nehal E. Elsadek, et al. · Biological and Pharmaceutical Bulletin · 4
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Using PEGylated antigen-expressing extracellular vesicles to accomplish splenic B cell-targeted antigen delivery for induction of antibodies against SARS-CoV-2 spike protein
2025 · Sherif E. Emam, Nehal E. Elsadek, et al. · Journal of Pharmaceutical Sciences · 2
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The Impact of the Regional Ring Road on Urban Development (Case Study of Greater Cairo Region)
2022 · Nehal Elsadek, Ahmad Al-Menshawy, et al. · The Egyptian International Journal of Engineering Sciences and Technology · 1
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Contributors
2019 · Amr S. Abu Lila, Rosalía Agusti, et al. · Elsevier eBooks
Works count: 19
Citation count: 998
H-index: 12
I10-index: 14
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