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Ahmet Acar
Observed names:
A Acar,
A. Acar,
Acar, Ahmet,
Ahmet ACAR
Institution:
Middle East Technical University
Observed institutions:
Institute of Cancer Research,
Middle East Technical University,
Manchester Academic Health Science Centre,
Wellcome Centre for Cell-Matrix Research,
University of Manchester,
Cancer Research UK Manchester Institute
show all 6
ORCID:
0000-0002-2478-8029
Observed ORCID:
0000-0002-2478-8029
OpenAlex ID:
A5068086218
Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
2010
·
Yasushi Kojima
, Ahmet Acar
, et al.
·
Proceedings of the National Academy of Sciences
·
890
Experimental Generation of Carcinoma-Associated Fibroblasts (CAFs) from Human Mammary Fibroblasts
2011
·
Urszula M. Polanska
, Ahmet Acar
, et al.
·
Journal of Visualized Experiments
·
853
PDF
Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity
2015
·
Bruno M. Simões
, Ciara S. O’Brien
, et al.
·
Cell Reports
·
200
PDF
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer
2020
·
Ahmet Acar
, Daniel Nichol
, et al.
·
Nature Communications
·
137
Subclonal reconstruction of tumors by using machine learning and population genetics
2020
·
Giulio Caravagna
, Timon Heide
, et al.
·
Nature Genetics
·
129
PDF
TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast cancer
2013
·
S Busch
, A Acar
, et al.
·
Oncogene
·
120
Evolutionary dynamics of residual disease in human glioblastoma
2018
·
I. Spiteri
, G. Caravagna
, et al.
·
Annals of Oncology
·
90
PDF
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors
2023
·
Luis Zapata
, Giulio Caravagna
, et al.
·
Nature Genetics
·
73
PDF
Dishevelled limits Notch signalling through inhibition of CSL
2012
·
Giovanna M. Collu
, Ana Hidalgo-Sastre
, et al.
·
Development
·
71
Inhibition of Wnt signalling by Notch via two distinct mechanisms
2021
·
Ahmet Acar
, Ana Hidalgo-Sastre
, et al.
·
Scientific Reports
·
70
PDF
A Role for Notch Signalling in Breast Cancer and Endocrine Resistance
2016
·
Ahmet Acar
, Bruno M. Simões
, et al.
·
Stem Cells International
·
62
PDF
Epigenetic Heritability of Cell Plasticity Drives Cancer Drug Resistance through a One-to-Many Genotype-to-Phenotype Paradigm
2025
·
Erica Oliveira
, Salvatore Milite
, et al.
·
Cancer Research
·
46
PDF
The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer
2018
·
Peter Barry
, Alexandra Vatsiou
, et al.
·
Clinical Cancer Research
·
43
Tumor evolution metrics predict recurrence beyond 10 years in locally advanced prostate cancer
2024
·
Javier Fernandez-Mateos
, George D. Cresswell
, et al.
·
Nature Cancer
·
32
PDF
Current Technologies and Future Perspectives in Immunotherapy towards a Clinical Oncology Approach
2024
·
Subhamay Adhikary
, Surajit Pathak
, et al.
·
Biomedicines
·
28
PDF
Systems Biology and Experimental Model Systems of Cancer
2020
·
Gizem Damla Yalcin
, Nurseda Danisik
, et al.
·
Journal of Personalized Medicine
·
24
PDF
Exploiting Matrix Stiffness to Overcome Drug Resistance
2024
·
Hakan Berk Aydin
, Altug Ozcelikkale
, et al.
·
ACS Biomaterials Science & Engineering
·
23
Optimizing cancer therapy: a review of the multifaceted effects of metronomic chemotherapy
2024
·
Oyku Yagmur Basar
, Sawsan Mohammed
, et al.
·
Frontiers in Cell and Developmental Biology
·
18
PDF
Benchmarking long-read structural variant calling tools and combinations for detecting somatic variants in cancer genomes
2025
·
Safa Kerem Aydin
, Kubra Celikbas Yilmaz
, et al.
·
Scientific Reports
·
17
Increased TRIM31 gene expression is positively correlated with SARS-CoV-2 associated genes TMPRSS2 and TMPRSS4 in gastrointestinal cancers
2022
·
Mehmet Arda Temena
, Ahmet Acar
·
Scientific Reports
·
17
PDF
Patient-derived tumor organoids: advances, applications, and future directions in biomedical research
2026
·
Ahmet Acar
·
Frontiers in Medicine
·
16
PDF
Identification of collateral sensitivity and evolutionary landscape of chemotherapy-induced drug resistance using cellular barcoding technology
2023
·
Nurseda Danisik
, Kubra Celikbas Yilmaz
, et al.
·
Frontiers in Pharmacology
·
11
Engineered probiotics recruit CAR macrophages and establish immune memory to eradicate heterogeneous glioblastoma in mice
2026
·
Yulin Zhang
, Jianyu Shen
, et al.
·
Cell Host & Microbe
·
10
Investigation of evolutionary dynamics for drug resistance in 3D spheroid model system using cellular barcoding technology
2023
·
Gizem Damla Yalcin
, Kubra Celikbas Yilmaz
, et al.
·
PLoS ONE
·
10
PDF
Colorectal cancer tumor grade segmentation: A new dataset and baseline results
2025
·
Duygu Arslan
, Sina Sehlaver
, et al.
·
Heliyon
·
9
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Works count:
110
Citation count:
3,064
H-index:
18
I10-index:
24
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