Product
Help
Pricing
About
Jobs
Log in
Get started
Author
Add to collection
Tadeusz J. Skarzynski
Observed names:
T Skarzynski,
T. SKARZYNSKI,
T. Skarzynski,
T. Skarżyński,
T.J. Skarzynski,
Tadeusz Skarzynski,
Tadeusz Skarżyński
show all 7
Institution:
Agilent Technologies (United Kingdom)
Observed institutions:
Brigham Young University,
Harvard University,
University of Leicester,
GlaxoSmithKline (United Kingdom),
University of Łódź,
University of Oxford,
Agilent Technologies (United Kingdom),
Imperial College London
show all 8
OpenAlex ID:
A5068193397
The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X‐ray crystallography.
1996
·
R. J. Lewis
, O. M. Singh
, et al.
·
The EMBO Journal
·
337
PDF
Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin
1996
·
Tadeusz Skarzynski
, Anil Mistry
, et al.
·
Structure
·
280
PDF
Structure of full-length porcine synovial collagenase reveals a C-terminal domain containing a calcium-linked, four-bladed β-propeller
1995
·
J Li
, P Brick
, et al.
·
Structure
·
260
PDF
Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. 2. Crystallographic and Molecular Modeling Study of Complexes of 4-Amino-4H-pyran-6-carboxamides and Sialidase from Influenza Virus Types A and B
1998
·
Neil R. Taylor
, Anne Cleasby
, et al.
·
Journal of Medicinal Chemistry
·
193
The high-resolution crystal structure of a 24-kDa gyrase B fragment fromE. coli complexed with one of the most potent coumarin inhibitors, clorobiocin
1997
·
Francis T.F. Tsai
, Onkar M.P. Singh
, et al.
·
Proteins Structure Function and Bioinformatics
·
156
The X-ray crystal structure of phosphomannose isomerase from Candida albicans at 1.7 Å resolution
1996
·
Anne Cleasby
, Alan Wonacott
, et al.
·
Nature Structural Biology
·
118
Crystal structure of α-dendrotoxin from the green mamba venom and its comparison with the structure of bovine pancreatic trypsin inhibitor
1992
·
Tadeusz Skarżyński
·
Journal of Molecular Biology
·
106
Coenzyme-induced conformational changes in glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus
1988
·
Tadeusz Skarżyński
, Alan J. Wonacott
·
Journal of Molecular Biology
·
101
Bonding of molecular oxygen to T state human haemoglobin
1984
·
Andrzej Brzozowski
, Zygmunt Derewenda
, et al.
·
Nature
·
99
Stereochemical Course of Enzymatic Enolpyruvyl Transfer and Catalytic Conformation of the Active Site Revealed by the Crystal Structure of the Fluorinated Analogue of the Reaction Tetrahedral Intermediate Bound to the Active Site of the C115A Mutant of MurA
1998
·
Tadeusz Skarzynski
, Dennis H. Kim
, et al.
·
Biochemistry
·
69
Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamides
1996
·
Paul W. Smith
, Steven L. Sollis
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
55
Crystal structure of the Ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA
2000
·
Luca Jovine
, Tobias Hainzl
, et al.
·
Structure
·
54
PDF
Probing the coenzyme specificity of glyceraldehyde-3-phosphate dehydrogenases by site-directed mutagenesis
1990
·
C. Corbier
, S. Clermont
, et al.
·
Biochemistry
·
52
Crystallization of Inhibitor Complexes of an N-Terminal 24 kDa Fragment of the DNA Gyrase B Protein
1994
·
Richard J. Lewis
, Onkar M.P. Singh
, et al.
·
Journal of Molecular Biology
·
50
The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase—GW311616A a development candidate
2001
·
Simon J.F Macdonald
, Michael D Dowle
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
48
Synthesis and evaluation of novel α-amino cyclic boronates as inhibitors of HCV NS3 protease
2010
·
Xianfeng Li
, Yong-Kang Zhang
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
46
Collecting data in the home laboratory: evolution of X-ray sources, detectors and working practices
2013
·
Tadeusz Skarzynski
·
Acta Crystallographica Section D Biological Crystallography
·
45
PDF
Novel macrocyclic HCV NS3 protease inhibitors derived from α-amino cyclic boronates
2010
·
Xianfeng Li
, Yong-Kang Zhang
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
36
Crystal structures of ASK1‐inhibtor complexes provide a platform for structure‐based drug design
2013
·
Onkar Singh
, Anthony Shillings
, et al.
·
Protein Science
·
27
PDF
Industrial perspective on X-ray data collection and analysis
2005
·
Tadeusz Skarzynski
, James Thorpe
·
Acta Crystallographica Section D Biological Crystallography
·
25
PDF
Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 Urea Leads to Potent Intracellular Inhibitors of Hepatitis C Virus NS3/4A Protease
2003
·
Martin J. Slater
, Elizabeth M. Amphlett
, et al.
·
Organic Letters
·
17
Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine- trans -lactams
2001
·
Simon J.F Macdonald
, Michael D Dowle
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
14
Pyrrolidine-5,5-trans-lactams. 2. The Use of X-ray Crystal Structure Data in the Optimization of P3 and P4 Substituents
2002
·
David M. Andrews
, Helene Chaignot
, et al.
·
Organic Letters
·
13
Crystallization and preliminary X-ray analysis of porcine synovial collagenase
1989
·
L.F. Lloyd
, T. Skarżyński
, et al.
·
Journal of Molecular Biology
·
13
New version ofCrysAlisProoptimized for automatic macromolecular data collection and processing
2011
·
T. Skarzynski
, M. Meyer
, et al.
·
Acta Crystallographica Section A Foundations of Crystallography
·
12
PDF
Show more works
View as search
Works count:
57
Citation count:
2,251
H-index:
20
I10-index:
25
Year
Topic
Type
