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Vanessa F. Langness

Observed names: Langness, Vanessa F., Langness, Vanessa Francine, Vanessa Langness
ORCID: 0000-0003-3140-3008
Observed ORCID: 0000-0003-3140-3008
OpenAlex ID: A5068214745
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons
2019 · Rik van der Kant, Vanessa F. Langness, et al. · Cell stem cell · 350
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Full-length amyloid precursor protein regulates lipoprotein metabolism and amyloid-β clearance in human astrocytes
2018 · Lauren K. Fong, Max M. Yang, et al. · Journal of Biological Chemistry · 73
Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization
2020 · Vanessa F. Langness, Rik van der Kant, et al. · Molecular Biology of the Cell · 42
A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity‐dependent synaptic and microglial transcriptomic changes in a late‐stage Alzheimer's mouse model
2024 · Amira Latif‐Hernandez, Tao Yang, et al. · Alzheimer s & Dementia · 13
Twenty years of therapeutic development in tauopathy mouse models: a scoping review
2025 · Vanessa F. Langness, Danielle A. Simmons, et al. · Alzheimer s & Dementia · 9
Small molecule modulation of the p75 neurotrophin receptor promotes dendritic spine resilience to pathogenic tau species and reduces their accumulation
2026 · Tao Yang, Yeonglong Ay, et al. · Acta Neuropathologica Communications · 3
A high‐throughput drug screen identifies berberine as a potent inducer of tau clearance
2020 · Rik van der Kant, Vanessa Langness, et al. · Alzheimer s & Dementia · 2
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A Small-Molecule TrkB Agonist Promotes Synaptic Resilience Against Aβ and Tau Oligomers and Mitigates Alterations in TrkB-Akt and Fyn Signaling
2026 · Tao Yang, Kevin C. Tran, et al. · Cells
Taming the “death receptor”: translating the first-in-class p75NTR modulator LM11A-31 from basic biology, across broad preclinical models, to clinical proof-of-concept
2026 · Vanessa F. Langness, Danielle A. Simmons, et al. · Journal of Translational Medicine
Small molecule modulation of the p75 neurotrophin receptor promotes dendritic spine resilience to pathogenic tau species and reduces their accumulation
2026 · Yang, Tao, Ay, Yeonglong, et al. · Figshare
Additional file 1 of Small molecule modulation of the p75 neurotrophin receptor promotes dendritic spine resilience to pathogenic tau species and reduces their accumulation
2026 · Yang, Tao, Ay, Yeonglong, et al. · Figshare
Works count: 12
Citation count: 492
H-index: 5
I10-index: 4
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