Author

Narendran G-Dayanandan

Observed name: N. G-Dayanandan

Institution: Microbiotix (United States)

Observed institutions: University of Connecticut, Pfizer (United States), Microbiotix (United States), University of Montana

ORCID: 0000-0002-8922-4339

Observed ORCID: 0000-0002-8922-4339

OpenAlex ID: A5068626422

Drugging the Folate Pathway in Mycobacterium Tuberculosis: The Role of Multi-Targeting Agents

2018 · Behnoush Hajian, Eric Scocchera, et al. · Cell chemical biology · 72

Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata

2014 · Narendran G-Dayanandan, Janet L. Paulsen, et al. · Journal of Medicinal Chemistry · 54

Crystal Structures of Trimethoprim-Resistant DfrA1 Rationalize Potent Inhibition by Propargyl-Linked Antifolates

2015 · Michael N. Lombardo, Narendran G-Dayanandan, et al. · ACS Infectious Diseases · 40

Elucidating Features That Drive the Design of Selective Antifolates Using Crystal Structures of Human Dihydrofolate Reductase

2013 · Kristen M. Lamb, Narendran G-Dayanandan, et al. · Biochemistry · 40

Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis

2016 · Behnoush Hajian, Eric Scocchera, et al. · PLoS ONE · 30

Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations

2016 · Stephanie M. Reeve, Eric Scocchera, et al. · Journal of Medicinal Chemistry · 30

Tandem Metathesis Reactions of Oxabicyclo[2.2.1]heptenes: Studies on the Spirocyclic Core of Cyclopamine

2011 · E. Zachary Oblak, Narendran G-Dayanandan, et al. · Organic Letters · 27

Unsaturated fatty acid perturbation combats emerging triazole antifungal resistance in the human fungal pathogen Aspergillus fumigatus

2024 · Cecilia Gutierrez-Perez, Charles Puerner, et al. · mBio · 16

Tropolone-induced effects on the unfolded protein response pathway and apoptosis in multiple myeloma cells are dependent on iron

2018 · Staci L. Haney, Michelle L. Varney, et al. · Leukemia Research · 13

Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates

2019 · M.N. Lombardo, N. G-Dayanandan, et al. · Drug Metabolism and Disposition · 9

Investigating N-arylpyrimidinamine (NAPA) compounds as early-stage inhibitors against human cytomegalovirus

2022 · Andrea J. Parsons, Sabrina I. Ophir, et al. · Antiviral Research · 4

Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks

2016 · Narendran G-Dayanandan, Eric W. Scocchera, et al. · Organic Letters · 4

trans-Translation inhibitors that kill Mycobacterium tuberculosis and pathogenic non-tuberculous mycobacteria also disrupt metal homeostasis

2026 · Akanksha Varshney, Ziyi Jia, et al. · Microbiology · 2

Identification and Characterization of a Metal Binding-Independent Rift Valley Fever Virus Endonuclease Inhibitor

2025 · Cara D. Kirby, Gai Liu, et al. · ACS Infectious Diseases · 1

Crystal structures of the resistance-conferring dfrA1 reveal that propargyl-linked antifolates are potent inhibitors

2016 · Michael N. Lombardo, Narendran G-Dayanandan, et al. · ACS Infectious Diseases

Works count: 15

Citation count: 342

H-index: 9

I10-index: 9