Get started
Author

Chris Eckman

Observed names: C. B. Eckman, C. Eckman, Eckman, C
OpenAlex ID: A5068770271
Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice
1996 · Karen Hsiao, Paul Chapman, et al. · Science · 4,208
Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP
2001 · Jada Lewis, Dennis W. Dickson, et al. · Science · 1,611
Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1
1996 · Karen Duff, Chris Eckman, et al. · Nature · 1,465
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
1998 · Leigh Holcomb, Marcia N. Gordon, et al. · Nature Medicine · 1,388
Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins
1995 · Karen K. Hsiao, David R. Borchelt, et al. · Neuron · 523
PDF
SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein
1999 · Costantino Iadecola, Fangyi Zhang, et al. · Nature Neuroscience · 400
The Arctic Alzheimer mutation facilitates early intraneuronal Aβ aggregation and senile plaque formation in transgenic mice
2005 · Anna Lord, Hannu Kalimo, et al. · Neurobiology of Aging · 258
A New Pathogenic Mutation in the APP Gene (I716V) Increases the Relative Proportion of A 42(43)
1997 · C. B. Eckman, N. D. Mehta, et al. · Human Molecular Genetics · 236
PDF
Increased Susceptibility to Ischemic Brain Damage in Transgenic Mice Overexpressing the Amyloid Precursor Protein
1997 · Fangyi Zhang, Chris Eckman, et al. · Journal of Neuroscience · 204
PDF
An Alzheimer's Disease-Linked PS1 Variant Rescues the Developmental Abnormalities of PS1-Deficient Embryos
1998 · Janine A Davis, Satoshi Naruse, et al. · Neuron · 131
PDF
Increased Aβ42(43) from cell lines expressing presenilin 1 mutations
1998 · Nitin D. Mehta, Lawrence M. Refolo, et al. · Annals of Neurology · 101
Twofold overexpression of human ?-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury
1998 · Hisayuki Murai, Jean E.S. Pierce, et al. · The Journal of Comparative Neurology · 89
Decreased Neprilysin Immunoreactivity in Alzheimer Disease, but Not in Pathological Aging
2005 · Deng-Shun Wang, Richard B. Lipton, et al. · Journal of Neuropathology & Experimental Neurology · 85
Antisense‐Induced Reduction of Presenilin 1 Expression Selectively Increases the Production of Amyloid β42 in Transfected Cells
1999 · Lawrence M. Refolo, Chris Eckman, et al. · Journal of Neurochemistry · 44
Truncated presenilin 2 derived from differentially spliced mRNAs does not affect the ratio of amyloid β-peptide 1-42/1-40
1998 · Jürgen Grünberg, Jochen Walter, et al. · Neuroreport · 17
Amyloid, PHF‐tau, Ubiquitin and Synaptic Markers in the Progression of Alzheimer's Disease: Immunochemical Analyses of Frontal Cortex from Prospectively Studied Elderly Humans
2001 · D. S. Wang, E. Cochran, et al. · 7
Live discussion: Amyloid-β degradation: The forgotten half of Alzheimer's disease1
2004 · Chastity Whitaker, Chris Eckman, et al. · Journal of Alzheimer s Disease · 3
PDF
Progressive changes in amyloid, apolipoprotein-E, synaptic markers and ubiquitin in frontal lobe of prospectively studied elderly humans
2000 · Deng-Shun Wang, Elizabeth J. Cochran, et al. · Neurobiology of Aging
Metabolism and Function of Presenilin 1
1998 · S. S. Sisodia, G. Thinakaran, et al. · Research and perspectives in Alzheimer's disease
Correlative MemoryDeficits, AP3 Elevation, and Amyloid Plaques inTransgenic Mice
1996 · Chris Eckman, Steven G. Younkin, et al.
Works count: 21
Citation count: 10,770
H-index: 15
I10-index: 15
Year
Topic
Type