Author

M. Gertz

Observed names: Gertz, Melanie, Gertz, Melanie (Dipl.), Melanie Gertz

Institution: University of Bayreuth

Observed institutions: University of Bayreuth, Ruhr University Bochum

OpenAlex ID: A5068993629

Substrates and Regulation Mechanisms for the Human Mitochondrial Sirtuins Sirt3 and Sirt5

2008 · Christine Schlicker, Melanie Gertz, et al. · Journal of Molecular Biology · 526

Ex-527 inhibits Sirtuins by exploiting their unique NAD + -dependent deacetylation mechanism

2013 · Melanie Gertz, Frank Fischer, et al. · Proceedings of the National Academy of Sciences · 317

PDF

A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol

2012 · Melanie Gertz, Giang Thi Tuyet Nguyen, et al. · PLoS ONE · 283

PDF

An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms

2013 · David Rauh, Frank Fischer, et al. · Nature Communications · 201

PDF

Structure and Inhibition of the CO2-Sensing Carbonic Anhydrase Can2 from the Pathogenic Fungus Cryptococcus neoformans

2008 · Christine Schlicker, Rebecca A. Hall, et al. · Journal of Molecular Biology · 199

A Phosphodiesterase 2A Isoform Localized to Mitochondria Regulates Respiration

2011 · Rebeca Acin-Perez, Michael Russwurm, et al. · Journal of Biological Chemistry · 136

Sirt5 Deacylation Activities Show Differential Sensitivities to Nicotinamide Inhibition

2012 · Frank Fischer, Melanie Gertz, et al. · PLoS ONE · 88

PDF

Structural and functional features of a collagen-binding matrix protein from the mussel byssus

2014 · Michael H. Suhre, Melanie Gertz, et al. · Nature Communications · 86

PDF

Activation of the lifespan regulator p66 Shc through reversible disulfide bond formation

2008 · Melanie Gertz, Frank Fischer, et al. · Proceedings of the National Academy of Sciences · 81

The Lifespan-Regulator p66Shc in Mitochondria: Redox Enzyme or Redox Sensor?

2010 · Melanie Gertz, Clemens Steegborn · Antioxidants and Redox Signaling · 75

Function and regulation of the mitochondrial Sirtuin isoform Sirt5 in Mammalia

2009 · Melanie Gertz, Clemens Steegborn · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 74

Chemical Probing of the Human Sirtuin 5 Active Site Reveals Its Substrate Acyl Specificity and Peptide‐Based Inhibitors

2014 · Claudia Roessler, Theresa Nowak, et al. · Angewandte Chemie International Edition · 73

Crystal Structures of Sirt3 Complexes with 4′-Bromo-Resveratrol Reveal Binding Sites and Inhibition Mechanism

2013 · Giang Thi Tuyet Nguyen, Melanie Gertz, et al. · Chemistry & Biology · 73

PDF

Using mitochondrial sirtuins as drug targets: disease implications and available compounds

2016 · Melanie Gertz, Clemens Steegborn · Cellular and Molecular Life Sciences · 70

Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD + and SRT1720: binding details and inhibition mechanism

2013 · Giang Thi Tuyet Nguyen, Susanne Schaefer, et al. · Acta Crystallographica Section D Biological Crystallography · 66

Identification of Peroxiredoxin 1 as a novel interaction partner for the lifespan regulator protein p66Shc

2009 · Melanie Gertz, Frank Fischer, et al. · Aging · 63

PDF

Chemical Probing of the Human Sirtuin 5 Active Site Reveals Its Substrate Acyl Specificity and Peptide‐Based Inhibitors

2014 · Claudia Roessler, Theresa Nowak, et al. · Angewandte Chemie · 11

Interactions of rotor subunits in the chloroplast ATP synthase modulated by nucleotides and by Mg2+

2007 · Melanie Gertz, Holger Seelert, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 11

Crystallization and preliminary X-ray diffraction analysis of proximal thread matrix protein 1 (PTMP1) fromMytilus galloprovincialis

2014 · Michael H. Suhre, Thomas Scheibel, et al. · Acta Crystallographica Section F Structural Biology Communications · 7

PDF

The mitochondrial apoptosis pathway and p66Shc: A regulatory redox enzyme or an adapter protein snuggling around?

2010 · Melanie Gertz, Clemens Steegborn · Cell Cycle · 5

PDF

Crystal structure of zebrafish Sirtuin 5 in complex with 2R-butyl- succinylated CPS1-peptide