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Modassir S. Choudhry

Observed names: M. Choudhry, Modassir Choudhry, Modassir S Choudhry
OpenAlex ID: A5069447766
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
2022 · Douglas C. Palmer, Beau R. Webber, et al. · Med · 80
Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial
2025 · Emil Lou, Modassir S Choudhry, et al. · The Lancet Oncology · 62
Improved Genome Packaging Efficiency of Adeno-associated Virus Vectors Using Rep Hybrids
2021 · Mario Mietzsch, Courtnee Eddington, et al. · Journal of Virology · 50
Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair
2023 · Beau R. Webber, Matthew J. Johnson, et al. · Nature Biomedical Engineering · 27
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Excision of an aneurysm of the left atrial appendage
2007 · Parsia A. Vagefi, Modassir Choudhry, et al. · Journal of Thoracic and Cardiovascular Surgery · 25
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Adeno-associated Virus (AAV) Capsid Chimeras with Enhanced Infectivity Reveal a Core Element in the AAV Genome Critical for both Cell Transduction and Capsid Assembly
2021 · Lydia Viney, Tilmann Bürckstümmer, et al. · Journal of Virology · 24
333 Targeting the apical intracellular checkpoint CISH unleashes T cell neoantigen reactivity and effector program
2020 · Douglas Palmer, Beau Webber, et al. · Regular and Young Investigator Award Abstracts · 12
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
2020 · Douglas Palmer, Beau Webber, et al. · Research Square · 12
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Genetic editing of CISH enhances T cell effector programs independently of immune checkpoint cell surface ligand expression
2021 · Elisa Arthofer, Krishnendu Chakraborty, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 6
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Virus Induced Lymphocytes (VIL) as a novel viral antigen-specific T cell therapy for COVID-19 and potential future pandemics
2021 · Rohan Sivapalan, Jinyan Liu, et al. · Scientific Reports · 6
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Characterization of local inflammatory response in an isolated lung perfusion model
1998 · Amir Abolhoda, Ari Brooks, et al. · Annals of Surgical Oncology · 6
Clinical manufacture of CRISPR/Cas9-based cytokine-induced SH2 protein knock-out tumor-infiltrating lymphocytes for gastrointestinal cancers
2025 · Matthew J. Johnson, Darin Sumstad, et al. · Cytotherapy · 5
A Bioinformatic and Empiric Exploration of Prokaryotic Argonautes as Novel Programmable Endonuclease Systems
2021 · Sejla Salic, Anna Sieber, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4
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CISH, a key intracellular checkpoint, in comparison and combination to existing and emerging cancer immune checkpoints
2026 · Florencia Cano, Alberto Bravo-Blas, et al. · Communications Biology · 1
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CISH, a novel intracellular immune checkpoint, in comparison and combination to existing and emerging cancer immune checkpoints
2025 · Florencia Cano, Alberto Bravo Blas, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Abstract CT269: First-in-human trial in patients with metastatic colorectal cancer using CRISPR-engineered tumor infiltrating lymphocytes in which the intracellular immune checkpoint CISH is inhibited
2025 · Emil Lou, Modassir S. Choudhry, et al. · Cancer Research · 1
A genetically engineered, stem-cell-derived cellular vaccine
2022 · Amanda Cooper, Adam Sidaway, et al. · Cell Reports Medicine · 1
Homology mediated end joining enables efficient non-viral targeted integration of large DNA templates in primary human T cells
2021 · Beau R. Webber, Matthew J. Johnson, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Bispecific CD20xCD40 Antibodies Achieve Multi-Lineage Modulation of Humoral and Cellular Immunity
2025 · Ben McLaughlin, Mark De Boer, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
2025 · Matthew J. Johnson, Anthony P. DeFeo, et al. · Journal of Visualized Experiments
Gene Editing/Gene Therapies: CLINICAL MANUFACTURE OF CRISPR/CAS9-BASED CYTOKINE-INDUCED SH2 PROTEIN (CISH) KNOCK-OUT (KO) TUMOR-INFILTRATING LYMPHOCYTES (TIL) FOR GASTROINTESTINAL (GI) CANCERS
2022 · D. Sumstad, B. Webber, et al. · Cytotherapy
A Novel CRISPR-Engineered, Stem Cell-Derived Cellular Vaccine
2021 · Krishnendu Chakraborty, Abishek Chandrashekar, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Internal Checkpoint Regulates T Cell Neoantigen Reactivity and Susceptibility to PD1 Blockade
2020 · Douglas C. Palmer, Beau R. Webber, et al. · SSRN Electronic Journal
Works count: 23
Citation count: 323
H-index: 8
I10-index: 8
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