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Vinay R. Sonawane

Observed names: V Sonawane, V. Sonawane, V.R. Sonawane, Vinay Sonawane, vinay sonawane
Institution: Cipla (India)
ORCID: 0000-0003-0128-5581
Observed ORCID: 0000-0003-0128-5581
OpenAlex ID: A5069550959
Quinazoline derivatives as selective CYP1B1 inhibitors
2017 · Mohd Usman Mohd Siddique, Glen J.P. McCann, et al. · European Journal of Medicinal Chemistry · 60
Cyclin-dependent kinase inhibitor, P276-00 induces apoptosis in multiple myeloma cells by inhibition of Cdk9-T1 and RNA polymerase II-dependent transcription
2011 · Sonal M. Manohar, Maggie J. Rathos, et al. · Leukemia Research · 58
Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines
2017 · Neill J. Horley, Kenneth J.M. Beresford, et al. · European Journal of Medicinal Chemistry · 56
Cink4T, a quinazolinone-based dual inhibitor of Cdk4 and tubulin polymerization, identified via ligand-based virtual screening, for efficient anticancer therapy
2019 · Vinay Sonawane, Mohd Usman Mohd Siddique, et al. · European Journal of Medicinal Chemistry · 48
Identification of Potent and Selective CYP1A1 Inhibitors via Combined Ligand and Structure-Based Virtual Screening and Their in Vitro Validation in Sacchrosomes and Live Human Cells
2017 · Prashant Joshi, Glen J. P. McCann, et al. · Journal of Chemical Information and Modeling · 41
Biphenyl urea derivatives as selective CYP1B1 inhibitors
2016 · Mohd Usman Mohd Siddique, Glen J. P. McCann, et al. · Organic & Biomolecular Chemistry · 37
Khellinoflavanone, a Semisynthetic Derivative of Khellin, Overcomes Benzo[ a ]pyrene Toxicity in Human Normal and Cancer Cells That Express CYP1A1
2018 · Rajni Sharma, Ibidapo S. Williams, et al. · ACS Omega · 24
A novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells
2011 · Sonal M Manohar, Amol A Padgaonkar, et al. · BMC Cancer · 22
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Identification of karanjin isolated from the Indian beech tree as a potent CYP1 enzyme inhibitor with cellular efficacy via screening of a natural product repository
2018 · Prashant Joshi, Vinay R. Sonawane, et al. · MedChemComm · 19
CYP enzymes, expressed within live human suspension cells, are superior to widely-used microsomal enzymes in identifying potent CYP1A1/CYP1B1 inhibitors: Identification of quinazolinones as CYP1A1/CYP1B1 inhibitors that efficiently reverse B[a]P toxicity and cisplatin resistance
2019 · Vinay R. Sonawane, Mohd Usman Mohd Siddique, et al. · European Journal of Pharmaceutical Sciences · 18
(E)-3-(3,4,5-Trimethoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one, a heterocyclic chalcone is a potent and selective CYP1A1 inhibitor and cancer chemopreventive agent
2017 · Neill J. Horley, Kenneth J.M. Beresford, et al. · Bioorganic & Medicinal Chemistry Letters · 17
Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells
2018 · Rajni Sharma, Ibidapo S. Williams, et al. · Bioorganic & Medicinal Chemistry · 16
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P7170, a novel inhibitor of mTORC1/mTORC2 and Activin receptor-like Kinase 1 (ALK1) inhibits the growth of non small cell lung cancer
2014 · Venkatasubbaiah A Venkatesha, Asavari Joshi, et al. · Molecular Cancer · 13
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Ketorolac modulates Rac-1/HIF-1α/DDX3/β-catenin signalling via a tumor suppressor prostate apoptosis response-4 (Par-4) in renal cell carcinoma
2023 · Vinay Sonawane, Jeevan Ghosalkar, et al. · Scientific Reports · 11
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Prostate Apoptosis Response-4 (Par-4): A Novel Target in Pyronaridine-Induced Apoptosis in Glioblastoma (GBM) Cells
2022 · Jeevan Ghosalkar, Vinay Sonawane, et al. · Cancers · 11
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Pharmacological inhibition of hypoxia induced acidosis employing a CAIX inhibitor sensitizes gemcitabine resistant PDAC cells
2025 · Jeevan Ghosalkar, Vinay Sonawane, et al. · Scientific Reports · 8
Effect of low doses and low dose-rates of gamma radiation on DNA damage in human peripheral blood leukocytes using comet assay
2005 · R.C. Chaubey, H.N. Bhilwade, et al. · International Journal of Low Radiation · 5
Optimization of an method for assessing pulmonary permeability of inhaled drugs using alveolar epithelial cells
2024 · Nitesh Shirsath, Rohit Chaudhari, et al. · Journal of Pharmacological and Toxicological Methods · 3
Mechanisms of cancer cell rescue against pancreatic cancer therapeutics: Intrinsic and acquired resistance
2025 · Jeevan Ghosalkar, Vinay Sonawane, et al. · Journal of Cancer Biology · 2
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Abstract 2013: A carbonic anhydrase inhibitor methazolamide potentiates efficacy of gemcitabine by modulating anti-proliferative activity and cancer stem cell markers in pancreatic carcinoma
2019 · Kalpana Joshi, Jeevan D. Ghosalkar, et al. · Cancer Research · 2
Prostate Apoptosis Response-4: a Therapeutic Target for Malignant Gliomas
2021 · Jeevan Ghosalkar, Vinay Sonawane, et al. · Springer eBooks · 1
Abstract 2013: A carbonic anhydrase inhibitor methazolamide potentiates efficacy of gemcitabine by modulating anti-proliferative activity and cancer stem cell markers in pancreatic carcinoma
2019 · Kalpana Joshi, Jeevan D. Ghosalkar, et al. · Tumor Biology · 1
Abstract 4521: P7170, a novel inhibitor of phosphoinositide 3-kinase (PI3K)-mammalian target of rapamycin (mTOR) and activin receptor-like kinase 1 (ALK1) shows anti-tumor activity in triple negative breast cancer
2014 · Veena R. Agarwal, Dimple Bhatia, et al. · Cancer Research · 1
Abstract 251: Anti-malarial drug Pyronaridine modulates microenvironment leading to potent anti-cancer activity against GBM
2019 · Jeevan D. Ghosalkar, Vinay R. Sonawane, et al. · Cancer Research
Abstract 251: Anti-malarial drug Pyronaridine modulates microenvironment leading to potent anti-cancer activity against GBM
2019 · Jeevan D. Ghosalkar, Vinay R. Sonawane, et al. · Experimental and Molecular Therapeutics
Works count: 30
Citation count: 474
H-index: 13
I10-index: 15
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