Author

Becky A. Penhallow

Observed names: B Penhallow, Becky Penhallow

Observed institution: Bristol-Myers Squibb (United States)

OpenAlex ID: A5069719379

Discovery of (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity

2000 · John T. Hunt, Charles Z. Ding, et al. · Journal of Medicinal Chemistry · 134

Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors

2008 · Petra Ross-Macdonald, Heshani de Silva, et al. · Molecular Cancer Therapeutics · 130

Selective Itk Inhibitors Block T-Cell Activation and Murine Lung Inflammation

2004 · Tai-An Lin, Kim W. McIntyre, et al. · Biochemistry · 111

Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2

2011 · A V Purandare, T M McDevitt, et al. · Leukemia · 77

Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors

2006 · Jagabandhu Das, Joseph A. Furch, et al. · Bioorganic & Medicinal Chemistry Letters · 74

Renal Cell Carcinoma (RCC) Tumors Display Large Expansion of Double Positive (DP) CD4+CD8+ T Cells With Expression of Exhaustion Markers

2018 · Laurence C. Menard, Paul Fischer, et al. · Frontiers in Immunology · 57

Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase

1999 · Charles Z. Ding, Roberta Batorsky, et al. · Journal of Medicinal Chemistry · 41

Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms

2015 · Honghe Wan, Gretchen M. Schroeder, et al. · ACS Medicinal Chemistry Letters · 40

Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors

2006 · Jagabandhu Das, Chunjian Liu, et al. · Bioorganic & Medicinal Chemistry Letters · 36

Transcriptional Profiling of the Dose Response: A More Powerful Approach for Characterizing Drug Activities

2009 · Rui-Ru Ji, Heshani de Silva, et al. · PLoS Computational Biology · 35

Modulation of cofilin phosphorylation by inhibition of the Lim family kinases

2012 · Liqi He, Steven P. Seitz, et al. · Bioorganic & Medicinal Chemistry Letters · 23

Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists

2012 · Gretchen M. Schroeder, Donna Wei, et al. · Bioorganic & Medicinal Chemistry Letters · 22

Abstract LB-127: From bench to bedside: Exploring OX40 receptor modulation in a phase 1/2a study of the OX40 costimulatory agonist BMS-986178 ± nivolumab (NIVO) or ipilimumab (IPI) in patients with advanced solid tumors

2018 · Rui Wang, Yan Feng, et al. · Cancer Research · 12

Corrigendum to “Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors” [Bioorg. Med. Chem. Lett. 16 (2006) 2411–2415]

2006 · Jagabandhu Das, Chunjian Liu, et al. · Bioorganic & Medicinal Chemistry Letters · 6

Abstract 5016: Antitumor activity of anti-PD-1 in combination with tyrosine kinase inhibitors in a preclinical renal cell carcinoma model

2014 · Gregg Masters, Gennaro Dito, et al. · Cancer Research · 4

Characterization of BMS-911543, a Functionally Selective Small Molecule Inhibitor of JAK2

2010 · Ashok V Purandare, Animesh Pardanani, et al. · Blood · 4

BMS-536924, a potent, small molecule inhibitor of the IGF-1 receptor in vitro and in vivo

2005 · Joan M. Carboni, Mark D. Wittman, et al. · Cancer Research · 2

Abstract 4687: Double positive (DP) CD4+CD8+ T cells with an exhausted phenotype in renal cell carcinoma (RCC) patients

2018 · Laurence Menard, Paul Fischer, et al. · Cancer Research · 1

Abstract DDT01-03: Discovery of BMS-911543, a highly selective JAK2 inhibitor, as a clinical candidate for the treatment of myeloproliferative disease and other malignancies

2011 · Ashok V. Purandare, Honghe Wan, et al. · Cancer Research · 1

Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase.

1999 · Charles Z. Ding, Roberta Batorsky, et al. · Journal of Medicinal Chemistry · 1

Supplementary Table S3 from Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors

2023 · Petra Ross-Macdonald, Heshani de Silva, et al.

Supplementary Table S2 from Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors

2023 · Petra Ross-Macdonald, Heshani de Silva, et al.

Supplementary Methods from Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors

2023 · Petra Ross-Macdonald, Heshani de Silva, et al.

Supplementary Table S4 from Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors

2023 · Petra Ross-Macdonald, Heshani de Silva, et al.

Supplementary Table S1 from Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors

2023 · Petra Ross-Macdonald, Heshani de Silva, et al.

Works count: 34

Citation count: 811

H-index: 12

I10-index: 13