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Yuehai Ke

Observed names: Ke, Yuehai, Y Ke, Y. Ke, Y.‐H. Ke, Yue-Hai Ke, Yue-hai Ke
Observed institutions: Boston Children's Hospital, Harvard University, Sanford Burnham Prebys Medical Discovery Institute, Xiamen University, Washington University in St. Louis, Sir Run Run Shaw Hospital, University of California San Diego, Model Animal Research Center, Institute of Immunology, Dana-Farber/Harvard Cancer Center, Zhejiang University-University of Edinburgh Institute, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Hangzhou Normal University Qianjiang College, Zhejiang University, Nanjing University
ORCID: 0000-0003-4146-1156
Observed ORCID: 0000-0003-4146-1156
OpenAlex ID: A5070102139
Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome
2016 · Chuansheng Guo, Shujun Xie, et al. · Immunity · 834
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MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2
2010 · Ling Ding, Yanjun Xu, et al. · Cell Research · 341
Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages
2021 · Yuxian Guo, Yaru Liu, et al. · Nature Communications · 193
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Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome
2016 · Chuansheng Guo, Shujun Xie, et al. · Immunity · 174
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PTEN regulation by Akt–EGR1–ARF–PTEN axis
2008 · Jianxiu Yu, Sharon S Zhang, et al. · The EMBO Journal · 139
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Deletion of Shp2 in the Brain Leads to Defective Proliferation and Differentiation in Neural Stem Cells and Early Postnatal Lethality
2007 · Yuehai Ke, Eric E. Zhang, et al. · Molecular and Cellular Biology · 123
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Myeloid-Specific Disruption of Tyrosine Phosphatase Shp2 Promotes Alternative Activation of Macrophages and Predisposes Mice to Pulmonary Fibrosis
2014 · Bo Tao, Wei Jin, et al. · The Journal of Immunology · 116
Endothelial deletion of SHP2 suppresses tumor angiogenesis and promotes vascular normalization
2021 · Zhiyong Xu, Chunyi Guo, et al. · Nature Communications · 99
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Phosphatase Shp2 exacerbates intestinal inflammation by disrupting macrophage responsiveness to interleukin-10
2019 · Peng Xiao, Huilun Zhang, et al. · The Journal of Experimental Medicine · 96
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Conditional Deletion of Shp2 Tyrosine Phosphatase in Thymocytes Suppresses Both Pre-TCR and TCR Signals
2006 · Thanh V Nguyen, Yuehai Ke, et al. · The Journal of Immunology · 87
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Role of Gab2 in mammary tumorigenesis and metastasis
2007 · Y Ke, D Wu, et al. · Oncogene · 84
Mannose metabolism normalizes gut homeostasis by blocking the TNF-α-mediated proinflammatory circuit
2022 · Peng Xiao, Ziwei Hu, et al. · Cellular and Molecular Immunology · 82
Stem cells applications in bone and tooth repair and regeneration: New insights, tools, and hopes
2017 · Eiman Abdel Meguid, Yuehai Ke, et al. · Journal of Cellular Physiology · 75
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SHP2 deneddylation mediates tumor immunosuppression in colon cancer via the CD47/SIRPα axis
2023 · Yiqing Li, Hui Zhou, et al. · Journal of Clinical Investigation · 74
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Class III PI3K Positively Regulates Platelet Activation and Thrombosis via PI(3)P-Directed Function of NADPH Oxidase
2017 · Yangyang Liu, Mengjiao Hu, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 69
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Shp2 Plays an Important Role in Acute Cigarette Smoke-Mediated Lung Inflammation
2012 · Fen-fen Li, Jian Shen, et al. · The Journal of Immunology · 66
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Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1
2017 · Guotong Fu, Qin Xu, et al. · The Journal of Experimental Medicine · 65
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Conditional Deletion of Shp2 in the Mammary Gland Leads to Impaired Lobulo-alveolar Outgrowth and Attenuated Stat5 Activation
2006 · Yuehai Ke, Jacqueline Lesperance, et al. · Journal of Biological Chemistry · 61
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Increased levels of Gab1 and Gab2 adaptor proteins skew interleukin-4 (IL-4) signaling toward M2 macrophage-driven pulmonary fibrosis in mice
2017 · Xiaohong Guo, Tingting Li, et al. · Journal of Biological Chemistry · 58
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Manipulating the air-filled zebrafish swim bladder as a neutrophilic inflammation model for acute lung injury
2016 · Yuefei Zhang, Hongcui Liu, et al. · Cell Death and Disease · 58
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A dynamic real-time method for monitoring epithelial barrier function in vitro
2012 · Mingjiao Sun, Huiying Fu, et al. · Analytical Biochemistry · 57
A Conserved Mechanism for Control of Human and Mouse Embryonic Stem Cell Pluripotency and Differentiation by Shp2 Tyrosine Phosphatase
2009 · Dongmei Wu, Yuhong Pang, et al. · PLoS ONE · 57
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Selective Sequestration of STAT1 in the Cytoplasm via Phosphorylated SHP-2 Ameliorates Murine Experimental Colitis
2012 · Xingxin Wu, Wenjie Guo, et al. · The Journal of Immunology · 56
PDLIM5 inhibits STUB1-mediated degradation of SMAD3 and promotes the migration and invasion of lung cancer cells
2020 · Yueli Shi, Xinyu Wang, et al. · Journal of Biological Chemistry · 55
Myeloid-restricted ablation of Shp2 restrains melanoma growth by amplifying the reciprocal promotion of CXCL9 and IFN-γ production in tumor microenvironment
2018 · P. Xiao, Y. Guo, et al. · Oncogene · 54
Works count: 98
Citation count: 4,458
H-index: 37
I10-index: 69
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