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Manuel Johanns
Observed names:
Johanns, Manuel,
M. Johanns
Institutions:
Inserm,
Université de Lille,
Institut Pasteur de Lille,
Centre Hospitalier Universitaire de Lille,
de Duve Institute,
European Genomic Institute for Diabetes,
UCLouvain
show all 7
Observed institutions:
Inserm,
Université de Lille,
Institut Pasteur de Lille,
Centre Hospitalier Universitaire de Lille,
de Duve Institute,
Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires,
European Genomic Institute for Diabetes,
UCLouvain
show all 8
ORCID:
0000-0003-2536-5949
Observed ORCID:
0000-0003-2536-5949
OpenAlex ID:
A5070161381
AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B
2016
·
M. Johanns
, Y.-C. Lai
, et al.
·
Nature Communications
·
146
PDF
PPARs in liver physiology
2021
·
Alexandre Berthier
, Manuel Johanns
, et al.
·
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
·
129
PDF
Specific post-translational modifications of soluble tau protein distinguishes Alzheimer’s disease and primary tauopathies
2023
·
Nathalie Kyalu Ngoie Zola
, Clémence Balty
, et al.
·
Nature Communications
·
104
PDF
TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise
2020
·
Yang Liu
, Phong T. Nguyen
, et al.
·
Nature
·
87
Direct and indirect activation of eukaryotic elongation factor 2 kinase by AMP-activated protein kinase
2017
·
M. Johanns
, S. Pyr dit Ruys
, et al.
·
Cellular Signalling
·
78
Role of Akt/PKB and PFKFB isoenzymes in the control of glycolysis, cell proliferation and protein synthesis in mitogen-stimulated thymocytes
2017
·
Amina Houddane
, Laurent Bultot
, et al.
·
Cellular Signalling
·
76
AMPK inhibits liver gluconeogenesis: fact or fiction?
2023
·
Manuel Johanns
, Louis Hue
, et al.
·
Biochemical Journal
·
47
Lactate dehydrogenase A-coupled NAD+ regeneration is critical for acute myeloid leukemia cell survival
2025
·
Ayşegül Erdem
, Séléna Kaye
, et al.
·
Cancer & Metabolism
·
28
PDF
Genetic deletion of soluble 5′-nucleotidase II reduces body weight gain and insulin resistance induced by a high-fat diet
2019
·
Manuel Johanns
, Samanta Kviklyte
, et al.
·
Molecular Genetics and Metabolism
·
21
PDF
HBP1 phosphorylation by AKT regulates its transcriptional activity and glioblastoma cell proliferation
2018
·
Emeline Bollaert
, Manuel Johanns
, et al.
·
Cellular Signalling
·
18
Cellular uptake of proMMP-2:TIMP-2 complexes by the endocytic receptor megalin/LRP-2
2017
·
Manuel Johanns
, Pascale Lemoine
, et al.
·
Scientific Reports
·
18
PDF
Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia
2019
·
Aphrodite T. Choumessi
, Manuel Johanns
, et al.
·
Biochemical Journal
·
15
Time-of-day-dependent variation of the human liver transcriptome and metabolome is disrupted in MASLD
2023
·
Manuel Johanns
, Joel T. Haas
, et al.
·
JHEP Reports
·
14
PDF
O-GlcNAcylation controls pro-fibrotic transcriptional regulatory signaling in myofibroblasts
2024
·
Ninon Very
, Clémence Boulet
, et al.
·
Cell Death and Disease
·
13
PDF
Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue
2020
·
Nusrat Hussain
, Sheng-Ju Chuang
, et al.
·
Biochemical Journal
·
11
Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators
2022
·
Manuel Johanns
, Cyril Corbet
, et al.
·
Biochemical Journal
·
9
AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue
2021
·
Sheng-Ju Chuang
, Manuel Johanns
, et al.
·
Biochemical Journal
·
8
The Molecular Circadian Clock Is a Target of Anti-cancer Translation Inhibitors
2023
·
Alexandre Berthier
, Céline Gheeraert
, et al.
·
Journal of Biological Rhythms
·
6
PDF
Unveiling the molecular legacy of transient insulin resistance: Implications for hepatic metabolic adaptability
2025
·
Alexandre Berthier
, Céline Gheeraert
, et al.
·
Journal of Hepatology
·
5
Comparison of Different Ex-Vivo Preservation Strategies on Cardiac Metabolism in an Animal Model of Donation after Circulatory Death
2023
·
Stefano Mastrobuoni
, Manuel Johanns
, et al.
·
Journal of Clinical Medicine
·
5
PDF
Stage-dependent tau post-translational modifications map the spatiotemporal progression of Alzheimer’s disease
2026
·
Axelle A.T. Vanparys
, Clémence Balty
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
4
PDF
Combined deletion of cytosolic 5′-nucleotidases IA and II lowers glycemia by improving skeletal muscle insulin action and lowering hepatic glucose production
2025
·
Roxane Jacobs
, Gaëtan Herinckx
, et al.
·
Journal of Biological Chemistry
·
4
PDF
The circadian clock controls hepatic stellate cell activation via a BMAL1/CK1ε/REV-ERBα/transgelin signaling pathway
2026
·
Manuel Johanns
, Alexandre Berthier
, et al.
·
Proceedings of the National Academy of Sciences
·
2
PDF
How mass spectrometry can be exploited to study AMPK
2024
·
Mark H. Rider
, Didier Vertommen
, et al.
·
Essays in Biochemistry
·
2
AMPK in the control of hepatic glucagon signalling and protein synthesis
2017
·
Manuel Johanns
·
Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B))
·
1
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Works count:
34
Citation count:
853
H-index:
13
I10-index:
15
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