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Stéphane Daffis
Observed names:
Daffis, Stephane,
S. Daffis,
Stephane Daffis
Institutions:
Drugs for Neglected Diseases Initiative,
Gilead Sciences (United States)
Observed institutions:
Drugs for Neglected Diseases Initiative,
Philipps University of Marburg,
Washington University in St. Louis,
Gilead Sciences (United States),
Gilead Sciences (France),
Bernhard Nocht Institute for Tropical Medicine
show all 6
ORCID:
0000-0003-0403-3670
Observed ORCID:
0000-0003-0403-3670
OpenAlex ID:
A5070412624
2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members
2010
·
Stephane Daffis
, Kristy J. Szretter
, et al.
·
Nature
·
963
PDF
Toll-Like Receptor 3 Has a Protective Role against West Nile Virus Infection
2008
·
Stephane Daffis
, Melanie A. Samuel
, et al.
·
Journal of Virology
·
371
Mastomys natalensis and Lassa Fever, West Africa
2006
·
Emilie Lecompte
, Elisabeth Fichet-Calvet
, et al.
·
Emerging infectious diseases
·
248
PDF
IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity
2010
·
Mehul S. Suthar
, Daphne Y. Ma
, et al.
·
PLoS Pathogens
·
229
PDF
Sustained efficacy and seroconversion with the Toll-like receptor 7 agonist GS-9620 in the Woodchuck model of chronic hepatitis B
2015
·
Stephan Menne
, Daniel B. Tumas
, et al.
·
Journal of Hepatology
·
220
West Nile Virus Noncoding Subgenomic RNA Contributes to Viral Evasion of the Type I Interferon-Mediated Antiviral Response
2012
·
Andrea Schuessler
, Anneke Funk
, et al.
·
Journal of Virology
·
210
Cell-Specific IRF-3 Responses Protect against West Nile Virus Infection by Interferon-Dependent and -Independent Mechanisms
2007
·
Stephane Daffis
, Melanie A Samuel
, et al.
·
PLoS Pathogens
·
198
PDF
Interferon Regulatory Factor IRF-7 Induces the Antiviral Alpha Interferon Response and Protects against Lethal West Nile Virus Infection
2008
·
Stephane Daffis
, Melanie A. Samuel
, et al.
·
Journal of Virology
·
174
The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection
2017
·
Congrong Niu
, Christine M. Livingston
, et al.
·
PLoS ONE
·
163
PDF
Fluctuation of Abundance and Lassa Virus Prevalence in Mastomys natalensis in Guinea, West Africa
2007
·
Elisabeth Fichet-Calvet
, Emilie Lecompte
, et al.
·
Vector-Borne and Zoonotic Diseases
·
162
Induction of IFN-β and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7
2009
·
Stephane Daffis
, Mehul S. Suthar
, et al.
·
PLoS Pathogens
·
134
PDF
Activation of the Cytokine Network and Unfavorable Outcome in Patients with Yellow Fever
2004
·
Jan ter Meulen
, Mohamed Sakho
, et al.
·
The Journal of Infectious Diseases
·
119
The Innate Immune Adaptor Molecule MyD88 Restricts West Nile Virus Replication and Spread in Neurons of the Central Nervous System
2010
·
Kristy J. Szretter
, Stephane Daffis
, et al.
·
Journal of Virology
·
115
Therapeutic Potential of TLR8 Agonist GS‐9688 (Selgantolimod) in Chronic Hepatitis B: Remodeling of Antiviral and Regulatory Mediators
2020
·
Oliver E. Amin
, Emily J. Colbeck
, et al.
·
Hepatology
·
111
PDF
A Temporal Role Of Type I Interferon Signaling in CD8+ T Cell Maturation during Acute West Nile Virus Infection
2011
·
Amelia K. Pinto
, Stephane Daffis
, et al.
·
PLoS Pathogens
·
111
PDF
Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism
2017
·
Congrong Niu
, Li Li
, et al.
·
Journal of Hepatology
·
106
Interferon Regulatory Factor-1 (IRF-1) Shapes Both Innate and CD8+ T Cell Immune Responses against West Nile Virus Infection
2011
·
James D. Brien
, Stephane Daffis
, et al.
·
PLoS Pathogens
·
100
PDF
The role of myristoylation in the membrane association of the Lassa virus matrix protein Z
2006
·
Thomas Strecker
, Anna Maisa
, et al.
·
Virology Journal
·
100
PDF
Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes
2018
·
Julie Lucifora
, Marc Bonnin
, et al.
·
Scientific Reports
·
88
PDF
Discovery of GS-9688 (Selgantolimod) as a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B
2020
·
Richard L. Mackman
, Michael Mish
, et al.
·
Journal of Medicinal Chemistry
·
87
Genetic identification of Kodoko virus, a novel arenavirus of the African pigmy mouse (Mus Nannomys minutoides) in West Africa
2007
·
E. Lecompte
, J. ter Meulen
, et al.
·
Virology
·
84
Toll‐Like Receptor 8 Agonist GS‐9688 Induces Sustained Efficacy in the Woodchuck Model of Chronic Hepatitis B
2020
·
Stephane Daffis
, Scott Balsitis
, et al.
·
Hepatology
·
75
PDF
Reproductive Characteristics of Mastomys natalensis and Lassa Virus Prevalence in Guinea, West Africa
2008
·
Elisabeth Fichet-Calvet
, Emilie LeCompte
, et al.
·
Vector-Borne and Zoonotic Diseases
·
72
The Naturally Attenuated Kunjin Strain of West Nile Virus Shows Enhanced Sensitivity to the Host Type I Interferon Response
2011
·
Stephane Daffis
, Helen M. Lazear
, et al.
·
Journal of Virology
·
70
Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope
2019
·
Xishan Lu
, Haixia Xiao
, et al.
·
Cell Reports
·
60
PDF
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Works count:
48
Citation count:
4,700
H-index:
29
I10-index:
33
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