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Lina M León
Observed names:
Leon, Lina Maria,
León, Lina M.,
Lina Leon,
Lina M Leon,
Lina M. Leon,
Lina M. León
show all 6
Institution:
Arsenal Biosciences (United States)
Observed institutions:
University of California, San Francisco,
Innovative Genomics Institute,
Arsenal Biosciences (United States),
University of California, Berkeley
ORCID:
0000-0002-1723-4044
Observed ORCID:
0000-0002-1723-4044
OpenAlex ID:
A5070756185
Works
13
Awards
1
Discovery of widespread type I and type V CRISPR-Cas inhibitors
2018
·
Nicole D. Marino
, Jenny Y. Zhang
, et al.
·
Science
·
279
A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases
2019
·
Senén D. Mendoza
, Eliza S. Nieweglowska
, et al.
·
Nature
·
243
PDF
A compact Cascade–Cas3 system for targeted genome engineering
2020
·
Bálint Csörgő
, Lina M. León
, et al.
·
Nature Methods
·
200
PDF
Mobile element warfare via CRISPR and anti-CRISPR in Pseudomonas aeruginosa
2021
·
Lina M León
, Allyson E Park
, et al.
·
Nucleic Acids Research
·
82
PDF
How bacteria control the CRISPR-Cas arsenal
2017
·
Lina M Leon
, Senén D Mendoza
, et al.
·
Current Opinion in Microbiology
·
29
PDF
334 Computational mapping of CAR-T cell exhaustion through single-cell perturbation screens
2024
·
Li Wang
, David DeTomaso
, et al.
·
Journal for ImmunoTherapy of Cancer
·
2
DINOcell: learning generalizable perturbation effects through self-distillation
2025
·
Jonathan Li
, Nilgun Tasdemir
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
245 Synthetic pathway activators (SPA) enhance CAR-T activity against solid tumors by reducing T cell exhaustion and increasing functional persistence in preclinical studies
2025
·
Lina M Leon
, Thomas J Gardner
, et al.
·
Journal for ImmunoTherapy of Cancer
PDF
1125 gx1: virtual target identification for overcoming T cell exhaustion
2025
·
Amaro Taylor-Weiner
, Sofia Kyriazopoulou Panagiotopoulou
, et al.
·
Journal for ImmunoTherapy of Cancer
PDF
282 Improving solid tumor CAR-T therapies by modulating T cell transcriptional states using combinatorial in vitro CRISPR screening followed by in vivo validation
2024
·
Lina M Leon
, Angela C Boroughs
, et al.
·
Journal for ImmunoTherapy of Cancer
CRISPR-Cas3: Studying the molecular interactions that drive adaptation & engineering novel bacterial editing tools
2021
·
Lina M. León
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Works count:
13
Citation count:
835
H-index:
5
I10-index:
5
Year
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