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Bin Tan

Progress and Challenges in Targeting the SARS-CoV-2 Papain-like Protease
2022 · Haozhou Tan, Yanmei Hu, et al. · Journal of Medicinal Chemistry · 171
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model
2024 · Bin Tan, Xiaoming Zhang, et al. · Science · 140
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SARS-CoV-2 Main Protease Drug Design, Assay Development, and Drug Resistance Studies
2022 · Bin Tan, Ryan Joyce, et al. · Accounts of Chemical Research · 111
Total Syntheses of Calyciphylline A-Type Alkaloids (−)-10-Deoxydaphnipaxianine A, (+)-Daphlongamine E and (+)-Calyciphylline R via Late-Stage Divinyl Carbinol Rearrangements
2022 · Yan Zhang, Yuye Chen, et al. · Journal of the American Chemical Society · 54
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Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates
2025 · Prakash Jadhav, Xueying Liang, et al. · Nature Communications · 37
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Exploring diverse reactive warheads for the design of SARS-CoV-2 main protease inhibitors
2023 · Bin Tan, Michael Sacco, et al. · European Journal of Medicinal Chemistry · 34
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Structure-based design of SARS-CoV-2 papain-like protease inhibitors
2023 · Prakash Jadhav, Bo Huang, et al. · European Journal of Medicinal Chemistry · 29
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Structure-Based Design of Covalent SARS-CoV-2 Papain-like Protease Inhibitors
2024 · Bin Tan, Xueying Liang, et al. · Journal of Medicinal Chemistry · 21
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A rationally designed 2C inhibitor prevents enterovirus D68-infected mice from developing paralysis
2025 · Kan Li, Michael J. Rudy, et al. · Nature Communications · 18
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Structure-Based Lead Optimization of Enterovirus D68 2A Protease Inhibitors
2023 · Bin Tan, Chang Liu, et al. · Journal of Medicinal Chemistry · 15
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Design, synthesis and biological activity evaluation of novel 4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl) oxy) pyridine-2-yl) amino derivatives as potent transforming growth factor-β (TGF-β) type I receptor inhibitors
2020 · Bin Tan, Xiaomeng Zhang, et al. · Bioorganic & Medicinal Chemistry Letters · 15
Stereospecific Effects of Benzimidazolonepiperidine Compounds on T-Type Ca2+Channels and Pain
2022 · Kimberly Gomez, Cheng Tang, et al. · ACS Chemical Neuroscience · 7
Structure-Based Design of Covalent SARS-CoV-2 Main Protease Inhibitors Targeting the Nirmatrelvir-Resistant E166 Mutants
2026 · Zhengjun Cai, Navita Kohaal, et al. · JACS Au · 5
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SARS-CoV-2 Papain-Like Protease: Drug Design, Assay Development, and Drug Resistance
2026 · Jun Wang, Kan Li, et al. · Accounts of Chemical Research
Structure-guided design of SARS-CoV-2 PLpro inhibitors with in vivo antiviral efficacy
2025 · Ahmadullah Ansari, Francesc Ruiz, et al. · Structural Dynamics
Works count: 15
Citation count: 657
H-index: 11
I10-index: 11
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