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Colin M. Tice

The use of spirocyclic scaffolds in drug discovery
2014 · Yajun Zheng, Colin M. Tice, et al. · Bioorganic & Medicinal Chemistry Letters · 1,046
Selecting the right compounds for screening: does Lipinski's Rule of 5 for pharmaceuticals apply to agrochemicals?
2001 · Colin M Tice · Pest Management Science · 308
The utilization of spirocyclic scaffolds in novel drug discovery
2016 · Ya-Jun Zheng, Colin M. Tice · Expert Opinion on Drug Discovery · 304
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Synthesis and SAR of cis-1-Benzoyl-1,2,3,4-tetrahydroquinoline ligands for control of gene expression in ecdysone responsive systems
2003 · Howard C Smith, Caitlin K Cavanaugh, et al. · Bioorganic & Medicinal Chemistry Letters · 75
Synthesis of sesquiterpene antitumor lactones. 10. Total synthesis of (.+-.)-parthenin
1982 · Clayton H. Heathcock, Colin M. Tice, et al. · Journal of the American Chemical Society · 62
Conformational control in structure-based drug design
2017 · Yajun Zheng, Colin M. Tice, et al. · Bioorganic & Medicinal Chemistry Letters · 59
Chemistry of naturally occurring polyamines. 8. Total synthesis of (+)-hypusine
1983 · Colin M. Tice, Bruce Ganem · The Journal of Organic Chemistry · 59
The Medicinal Chemistry of Liver X Receptor (LXR) Modulators
2014 · Colin M. Tice, Paul B. Noto, et al. · Journal of Medicinal Chemistry · 56
Highly Flexible Ligand Binding Pocket of Ecdysone Receptor
2004 · Mohan B. Kumar, David W. Potter, et al. · Journal of Biological Chemistry · 53
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Optimization of α-acylaminoketone ecdysone agonists for control of gene expression
2003 · Colin M. Tice, Robert E. Hormann, et al. · Bioorganic & Medicinal Chemistry Letters · 46
Synthesis and SAR of α-Acylaminoketone ligands for control of gene expression
2003 · Colin M Tice, Robert E Hormann, et al. · Bioorganic & Medicinal Chemistry Letters · 44
Structure-Based Design and Synthesis of 1,3-Oxazinan-2-one Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1
2011 · Zhenrong Xu, Colin M. Tice, et al. · Journal of Medicinal Chemistry · 40
Design, Synthesis, and Biological Evaluation of a Library of 1-(2-Thiazolyl)-5-(trifluoromethyl)pyrazole-4-carboxamides
2001 · Bridget A. Donohue, Enrique L. Michelotti, et al. · Journal of Combinatorial Chemistry · 40
Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist
2016 · Yajun Zheng, Linghang Zhuang, et al. · Journal of Medicinal Chemistry · 39
Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility
2011 · Lanqi Jia, Robert D. Simpson, et al. · ACS Medicinal Chemistry Letters · 38
PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication
2024 · Lori A. Emert-Sedlak, Colin M. Tice, et al. · Cell chemical biology · 36
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Selecting the right compounds for screening: use of surface‐area parameters
2002 · Colin M Tice · Pest Management Science · 36
Synthesis of sesquiterpene antitumor lactones. 8. An approach to the synthesis of pseudoguaianolides based on oxy-Cope rearrangement
1981 · Colin M. Tice, Clayton H. Heathcock · The Journal of Organic Chemistry · 32
Biochemical mode of action and differential activity of new ecdysone agonists against mosquitoes and moths
2005 · S. R. Palli, C. M. Tice, et al. · Archives of Insect Biochemistry and Physiology · 28
Non-canonical modulators of nuclear receptors
2016 · Colin M. Tice, Ya-Jun Zheng · Bioorganic & Medicinal Chemistry Letters · 27
Synthesis of a Sulfahydantoin Library
2001 · Fernando Albericio, Lois M. Bryman, et al. · Journal of Combinatorial Chemistry · 26
Spirocyclic ureas: Orally bioavailable 11β-HSD1 inhibitors identified by computer-aided drug design
2010 · Colin M. Tice, Wei Zhao, et al. · Bioorganic & Medicinal Chemistry Letters · 25
Renin Inhibitors
2006 · Colin M. Tice · Annual reports in medicinal chemistry · 25
Regiocontrolled synthesis of 3-substituted-6-trifluoromethyl-4(3H)-pyrimidinones
2001 · Colin M Tice, Lois M Bryman · Tetrahedron · 24
The chemistry of naturally occurring polyamines. 6. Efficient syntheses of N1- and N8-acetylspermidine
1983 · Colin M. Tice, Bruce Ganem · The Journal of Organic Chemistry · 23
Works count: 73
Citation count: 2,860
H-index: 24
I10-index: 40
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