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Franca Orsini

Versatility of the complement system in neuroinflammation, neurodegeneration and brain homeostasis
2014 · Franca Orsini, Daiana De Blasio, et al. · Frontiers in Cellular Neuroscience · 202
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Targeting Mannose-Binding Lectin Confers Long-Lasting Protection With a Surprisingly Wide Therapeutic Window in Cerebral Ischemia
2012 · Franca Orsini, Pia Villa, et al. · Circulation · 133
Recombinant C1 inhibitor in brain ischemic injury
2009 · Raffaella Gesuete, Claudio Storini, et al. · Annals of Neurology · 115
Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1
2016 · Franca Orsini, Elvina Chrysanthou, et al. · Journal of Neuroinflammation · 55
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Mannose-Binding Lectin Is Expressed After Clinical and Experimental Traumatic Brain Injury and Its Deletion Is Protective*
2014 · Luca Longhi, Franca Orsini, et al. · Critical Care Medicine · 51
Glial Cells Drive Preconditioning-Induced Blood-Brain Barrier Protection
2011 · Raffaella Gesuete, Franca Orsini, et al. · Stroke · 46
Pharmacological inhibition of mannose-binding lectin ameliorates neurobehavioral dysfunction following experimental traumatic brain injury
2016 · Daiana De Blasio, Stefano Fumagalli, et al. · Journal of Cerebral Blood Flow & Metabolism · 43
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Ficolin-3–mediated lectin complement pathway activation in patients with subarachnoid hemorrhage
2013 · Elisa R. Zanier, Rosalia Zangari, et al. · Neurology · 43
Human brain trauma severity is associated with lectin complement pathway activation
2018 · Daiana De Blasio, Stefano Fumagalli, et al. · Journal of Cerebral Blood Flow & Metabolism · 42
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Mannose-Binding Lectin Drives Platelet Inflammatory Phenotype and Vascular Damage After Cerebral Ischemia in Mice via IL (Interleukin)-1α
2018 · Franca Orsini, Stefano Fumagalli, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 40
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Mannose-binding lectin has a direct deleterious effect on ischemic brain microvascular endothelial cells
2019 · Laura Neglia, Stefano Fumagalli, et al. · Journal of Cerebral Blood Flow & Metabolism · 21
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Tau oligomers impair memory and synaptic plasticity through the cellular prion protein
2025 · Claudia Balducci, Franca Orsini, et al. · Acta Neuropathologica Communications · 16
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Proteomic analysis of mouse brain cortex identifies metabolic down‐regulation as a general feature of ischemic pre‐conditioning
2012 · Giacomo Scornavacca, Raffaella Gesuete, et al. · Journal of Neurochemistry · 16
A New Surface Plasmon Resonance Assay for In Vitro Screening of Mannose-Binding Lectin Inhibitors
2016 · Matteo Stravalaci, Daiana De Blasio, et al. · SLAS DISCOVERY · 10
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Genetic and pharmacologic enhancement of SUMO2 conjugation prevents and reverses cognitive impairment and synaptotoxicity in a preclinical model of Alzheimer's disease
2025 · Luana Fioriti, Nadeeja Wijesekara, et al. · Alzheimer s & Dementia · 8
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SARS-CoV-2 Nucleocapsid Protein Induces Tau Pathological Changes That Can Be Counteracted by SUMO2
2024 · Franca Orsini, Marco Bosica, et al. · International Journal of Molecular Sciences · 7
SUMO2 rescues neuronal and glial cells from the toxicity of P301L Tau mutant
2024 · Franca Orsini, Rosaria Pascente, et al. · Frontiers in Cellular Neuroscience · 5
SUMO2 Protects Against Tau-induced Synaptic and Cognitive Dysfunction
2022 · Franca Orsini, Elentina Argyrousi, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 5
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Corrigendum: Versatility of the complement system in neuroinflammation, neurodegeneration, and brain homeostasis
2015 · Franca Orsini, Daiana De Blasio, et al. · Frontiers in Cellular Neuroscience · 5
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A Combined Cell-Worm Approach to Search for Compounds Counteracting the Toxicity of Tau Oligomers In Vivo
2022 · Carmina Natale, Maria Monica Barzago, et al. · International Journal of Molecular Sciences · 2
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Mannose binding lectin as a target for cerebral ischemic injury
2011 · F. Orsini, S. Parrella, et al. · Molecular Immunology · 2
Glycan-coated nanoparticles mimicking the ischemic glycocalyx scavenge the complement system conferring protection after experimental ischemic stroke
2026 · Gizem Mansour, Serena Seminara, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Coiled-Coil Structures Mediate the Intercellular Propagation of Huntingtin
2026 · Bosica, Marco, Grasselli, Chiara, et al. · Zenodo (CERN European Organization for Nuclear Research)
Tau oligomers impair memory and synaptic plasticity through the cellular prion protein
2026 · Balducci, Claudia, Orsini, Franca, et al. · Zenodo (CERN European Organization for Nuclear Research)
Coiled-Coil Structures Mediate the Intercellular Propagation of Huntingtin
2025 · Marco Bosica, Chiara Grasselli, et al. · International Journal of Molecular Sciences
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Works count: 45
Citation count: 867
H-index: 13
I10-index: 14
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