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Timo Wille

Observed names: T Wille, T. Wille, Wille, T., Wille, Timo, Wille, Timo 1982-
Observed institutions: Public Health Agency of Canada, Universitätsmedizin Göttingen, Essen University Hospital, Bundeswehr Medical Service Academy, Institut für Pharmakologie und Toxikologie der Bundeswehr, Bundeswehr
ORCID: 0000-0002-4359-5388
Observed ORCID: 0000-0002-4359-5388
OpenAlex ID: A5071158849
Organophosphorus compounds and oximes: a critical review
2020 · Franz Worek, Horst Thiermann, et al. · Archives of Toxicology · 210
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Oximes in organophosphate poisoning: 60 years of hope and despair
2016 · Franz Worek, Horst Thiermann, et al. · Chemico-Biological Interactions · 181
Toxicology of organophosphorus compounds in view of an increasing terrorist threat
2016 · Franz Worek, Timo Wille, et al. · Archives of Toxicology · 135
Local sympathetic denervation attenuates myocardial inflammation and improves cardiac function after myocardial infarction in mice
2017 · Karin A Ziegler, Andrea Ahles, et al. · Cardiovascular Research · 102
Diagnostics and treatment of nerve agent poisoning—current status and future developments
2020 · Niko Amend, Karin V. Niessen, et al. · Annals of the New York Academy of Sciences · 66
Improvement of the cold storage of blood vessels with a vascular preservation solution. Study in porcine aortic segments
2008 · Timo Wille, Herbert de Groot, et al. · Journal of Vascular Surgery · 63
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Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro
2014 · Franz Worek, Thomas Seeger, et al. · Archives of Toxicology · 62
Reactivation kinetics of a series of related bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase—Structure–activity relationships
2012 · Franz Worek, Timo Wille, et al. · Biochemical Pharmacology · 59
Precision-Cut Lung Slices: Emerging Tools for Preclinical and Translational Lung Research: An Official American Thoracic Society Workshop Report
2024 · Mareike Lehmann, Ramaswamy Krishnan, et al. · American Journal of Respiratory Cell and Molecular Biology · 58
Kinetic analysis of interactions of paraoxon and oximes with human, Rhesus monkey, swine, rabbit, rat and guinea pig acetylcholinesterase
2010 · Franz Worek, Nadine Aurbek, et al. · Toxicology Letters · 54
Catalytic bioscavengers in nerve agent poisoning: A promising approach?
2015 · Franz Worek, Horst Thiermann, et al. · Toxicology Letters · 52
Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase
2015 · Michael Winter, Timo Wille, et al. · Toxicology Letters · 48
Detoxification of nerve agents by a substituted β-cyclodextrin: Application of a modified biological assay
2009 · T. Wille, O. Tenberken, et al. · Toxicology · 45
New modified β-cyclodextrin derivatives as detoxifying agents of chemical warfare agents (I). Synthesis and preliminary screening: Evaluation of the detoxification using a half-quantitative enzymatic assay
2012 · Raman Kumar Kalakuntla, Timo Wille, et al. · Toxicology Letters · 43
Reactivation of organophosphate-inhibited human, Cynomolgus monkey, swine and guinea pig acetylcholinesterase by MMB-4: A modified kinetic approach
2010 · Franz Worek, Timo Wille, et al. · Toxicology and Applied Pharmacology · 43
On-site analysis of acetylcholinesterase and butyrylcholinesterase activity with the ChE check mobile test kit—Determination of reference values and their relevance for diagnosis of exposure to organophosphorus compounds
2016 · Franz Worek, Martina Schilha, et al. · Toxicology Letters · 41
Drug development for the management of organophosphorus poisoning
2013 · Paul Wilhelm Elsinghorst, Franz Worek, et al. · Expert Opinion on Drug Discovery · 40
Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative defense
2021 · Jonas Tigges, Franz Worek, et al. · Archives of Toxicology · 37
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Chromenones as Multineurotargeting Inhibitors of Human Enzymes
2019 · Carina Lemke, Joscha Christmann, et al. · ACS Omega · 37
Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyrylcholinesterase
2014 · Gabriele Horn, Timo Wille, et al. · Archives of Toxicology · 36
Optimized strategies to synthesize β-cyclodextrin-oxime conjugates as a new generation of organophosphate scavengers
2011 · Romain Le Provost, Timo Wille, et al. · Organic & Biomolecular Chemistry · 34
In vitro detoxification of cyclosarin (GF) by modified cyclodextrins
2010 · Susanne Müller, Marianne Koller, et al. · Toxicology Letters · 34
Effectiveness of a substituted β-cyclodextrin to prevent cyclosarin toxicity in vivo
2014 · Franz Worek, Thomas Seeger, et al. · Toxicology Letters · 33
Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: Intraosseous versus intravenous injection
2016 · Timo Wille, Katharina Neumaier, et al. · Toxicology Letters · 31
In-vitro study of species-specific coagulation differences in animals and humans using rotational thromboelastometry (ROTEM)
2018 · Raimund Lechner, M Helm, et al. · Journal of the Royal Army Medical Corps · 30
Works count: 114
Citation count: 2,288
H-index: 28
I10-index: 57
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