Author

Paul M. Silber

Observed names: P. M. Silber, P. Silber, Paul M Silber, Paul Silber

Observed institutions: F. Hoffmann-La Roche AG, University of Arizona, Mary Kay (United States)

OpenAlex ID: A5071397188

Cryopreserved human hepatocytes: characterization of drug-metabolizing activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug–drug interaction potential

1999 · Albert P Li, Chuang Lu, et al. · Chemico-Biological Interactions · 304

Human and animal hepatocytes in vitro with extrapolation in vivo

2004 · Peter J. O′Brien, Katie Chan, et al. · Chemico-Biological Interactions · 102

Determination of cytochrome P450 1A2 and cytochrome P450 3A4 induction in cryopreserved human hepatocytes

2003 · Dirk Roymans, Cis Van Looveren, et al. · Biochemical Pharmacology · 71

Prediction of hepatic clearance using cryopreserved human hepatocytes: a comparison of serum and serum-free incubations

2006 · Nadège Blanchard, Nicola J Hewitt, et al. · Journal of Pharmacy and Pharmacology · 64

Identification of glutathione conjugates of troglitazone in human hepatocytes

2002 · Saileta Prabhu, Andrew Fackett, et al. · Chemico-Biological Interactions · 59

Structure–activity relationships for halobenzene induced cytotoxicity in rat and human hepatoctyes

2006 · Katie Chan, Neil S. Jensen, et al. · Chemico-Biological Interactions · 48

Differential in vitro hepatotoxicity of troglitazone and rosiglitazone among cryopreserved human hepatocytes from 37 donors

2002 · Scott Lloyd, Michael J Hayden, et al. · Chemico-Biological Interactions · 48

Maintenance of Liver Functions in Rat Hepatocytes Cultured as Spheroids in a Rotating Wall Vessel

2003 · Lanika A. Brown, Linda M. Arterburn, et al. · In Vitro Cellular & Developmental Biology - Animal · 44

Catechol-O-methyltransferase low activity genotype (COMTLL) is associated with low levels of COMT protein in human hepatocytes

2004 · Anne E. Sullivan Doyle, Julie E. Goodman, et al. · Cancer Letters · 28

The CTFA evaluation of alternatives program: an evaluation of In vitro alternatives to the draize primary eye irritation test (phase I) hydro-alcoholic formulations; a preliminary communication

1990 · S.D. Gettings, Louis C. DiPasquale, et al. · In vitro toxicology · 26

Adaptation of a γ-glutamyl transpeptidase assay to microtiter plates

1986 · Paul M. Silber, A.Jay Gandolfi, et al. · Analytical Biochemistry · 26

New Cytochrome P450 2d6*56 Allele Identified by Genotype/phenotype Analysis of Cryopreserved Human Hepatocytes

2006 · Li Li, Run-Mei Pan, et al. · Drug Metabolism and Disposition · 16

Early Biological Indicators of S-(1,2-Dichlorovinyl)-L-Cysteine Nephrotoxicity in the Rabbit

1986 · P. M. Silber, A. J. Gandolfi, et al. · Drug and Chemical Toxicology · 7

Comparative Skin Irritation of High and Low Spf Sunscreen Products

1989 · Paul M. Silber, Otto H. Mills, et al. · Journal of Toxicology Cutaneous and Ocular Toxicology · 3

An Estimate of the Number of Hepatocyte Donors Required to Provide Reasonable Estimates of Human Hepatic Clearance from In Vitro Experiments

2007 · James Byers, Kenneth Bachmann, et al. · Drug Metabolism Letters · 2

O-24 Independent regulation of intrarenal angiotensin receptors expression during the development of cyclosporine A-induced hypertension(KIDNEYS AND URINARY EXCRETION SYSTEM)(GENERAL SESSION BY ORAL PRESENTATION)(Proceedings of the 31st Annual Meeting)

2004 · Yumiko Iwase, Naoki Ohyama, et al. · The Journal of Toxicological Sciences · 2

Localized Eye Area Sensitivity Syndrome

1989 · Thomas J. Stephens, James P. McCulley, et al. · Journal of Toxicology Cutaneous and Ocular Toxicology · 2

P.1.048 Metabolism phenotype and in vitro drug-drug interaction studies with nemifitide, a novel pentapeptide antidepressant

2003 · G. Nicolau, J.P. Feighner, et al. · European Neuropsychopharmacology · 1

A Perfused Rotating Wall Vessel Bioartificial Liver

2002 · Sonya M. Hartley, Lanika A. Brown, et al. · ASAIO Journal · 1

On the comedogenic potential of quaternium-15 and DMDM hydantoin

1989 · Paul M. Silber, Thomas Stephens, et al. · 1

Comparison of Fresh and Cryopreserved Cynomolgus Monkey Hepatocyte Cytochrome P450 Levels in Induction Studies

2000 · Neil S. Jensen, Rebecca C. M, et al.

In Vitro Human Drug-Drug Interactions: Practices in the United States.

1996 · Paul M. Silber, Charles E. Ruegg, et al. · Drug Metabolism and Pharmacokinetics

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Predicting Human Drug Metabolism Interactions in Vitro: Current Practices in the United States

1995 · Paul M. Silber, Charles E. Ruegg · Drug Metabolism and Pharmacokinetics

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Early Indication and Pathogenesis of Renal Proximal Tubule Injury (enzymuria).

1987 · Paul M. Silber · UA Campus Repository (The University of Arizona)

Works count: 24

Citation count: 855

H-index: 12

I10-index: 12