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Dirk J. Snyders

Observed names: D J Snyders, D SNYDERS, D Snyders, D. J. Snyders, D. K. Snyders, D.J. Snyders, DIRK J. SNYDERS, DJ Snyders, Dirk J Snyders, Dirk Snyders, Dirk J. Snyders, Snyders, DJ, Snyders, Dirk, Snyders, Dirk J.
Observed institutions: Universidad Complutense de Madrid, Consejo Superior de Investigaciones Científicas, University of Antwerp, Vanderbilt University, Vlaams Instituut voor Biotechnologie, Vanderbilt University Medical Center
ORCID: 0000-0001-7142-6672
Observed ORCID: 0000-0001-7142-6672
OpenAlex ID: A5071594443
Class III antiarrhythmic agents have a lot of potential but a long way to go. Reduced effectiveness and dangers of reverse use dependence.
1990 · L M Hondeghem, D J Snyders · Circulation · 604
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A rapidly activating and slowly inactivating potassium channel cloned from human heart. Functional analysis after stable mammalian cell culture expression.
1993 · D J Snyders, M M Tamkun, et al. · The Journal of General Physiology · 265
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High affinity open channel block by dofetilide of HERG expressed in a human cell line.
1996 · D J Snyders, A Chaudhary · Molecular Pharmacology · 241
Structure and function of cardiac potassium channels
1999 · D Snyders · Cardiovascular Research · 202
Stereoselective Block of Cardiac Sodium Channels by Bupivacaine in Guinea Pig Ventricular Myocytes
1995 · Carmen Valenzuela, Dirk J. Snyders, et al. · Circulation · 198
Ibutilide, a Methanesulfonanilide Antiarrhythmic, Is a Potent Blocker of the Rapidly Activating Delayed Rectifier K + Current (I Kr ) in AT-1 Cells: Concentration-, Time-, Voltage-, and Use-Dependent Effects
1995 · Tao Yang, Dirk J. Snyders, et al. · Circulation · 189
Obligatory heterotetramerization of three previously uncharacterized Kv channel α-subunits identified in the human genome
2002 · N. Ottschytsch, A. Raes, et al. · Proceedings of the National Academy of Sciences · 172
Drug Block of I Kr : Model Systems and Relevance to Human Arrhythmias
2001 · Tao Yang, Dirk Snyders, et al. · Journal of Cardiovascular Pharmacology · 172
Rapid Inactivation Determines the Rectification and [K+]oDependence of the Rapid Component of the Delayed Rectifier K+Current in Cardiac Cells
1997 · Tao Yang, Dirk J. Snyders, et al. · Circulation Research · 171
Heteromultimeric assembly of human potassium channels. Molecular basis of a transient outward current?
1993 · S Po, S Roberds, et al. · Circulation Research · 170
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Stereoselective block of a human cardiac potassium channel (Kv1.5) by bupivacaine enantiomers
1995 · C. Valenzuela, E. Delpón, et al. · Biophysical Journal · 150
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A K+ Channel Splice Variant Common in Human Heart Lacks a C-terminal Domain Required for Expression of Rapidly Activating Delayed Rectifier Current
1998 · Sabina Kupershmidt, Dirk J. Snyders, et al. · Journal of Biological Chemistry · 146
Functional Differences in Kv1.5 Currents Expressed in Mammalian Cell Lines Are Due to the Presence of Endogenous Kvβ2.1 Subunits
1996 · Victor N. Uebele, Sarah K. England, et al. · Journal of Biological Chemistry · 131
Determinants of Antiarrhythmic Drug Action: Electrostatic and Hydrophobic Components of Block of the Human Cardiac hKv1.5 Channel
1995 · Dirk J. Snyders, Sarita W. Yeola · Circulation Research · 131
Molecular Analysis of a Binding Site for Quinidine in a Human Cardiac Delayed Rectifier K+Channel: Role of S6 in Antiarrhythmic Drug Binding
1996 · Sarita W. Yeola, Tom C. Rich, et al. · Circulation Research · 129
The contribution of genes involved in potassium-recycling in the inner ear to noise-induced hearing loss
2006 · Lut Van Laer, Per-Inge Carlsson, et al. · Human Mutation · 118
Quinidine delays IK activation in guinea pig ventricular myocytes.
1988 · D M Roden, P B Bennett, et al. · Circulation Research · 105
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Electrophysiological and pharmacological correspondence between Kv4.2 current and rat cardiac transient outward current
1997 · S YEOLA, D SNYDERS · Cardiovascular Research · 103
Electrically Silent Kv Subunits: Their Molecular and Functional Characteristics
2012 · Elke Bocksteins, Dirk J. Snyders · Physiology · 98
A Novel Mutation (T65P) in the PAS Domain of the Human Potassium Channel HERG Results in the Long QT Syndrome by Trafficking Deficiency
2002 · Aimée Paulussen, Adam Raes, et al. · Journal of Biological Chemistry · 97
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Class III Antiarrhythmic Effects of Zatebradine: Time-, State-, Use-, and Voltage-Dependent Block of hKv1.5 Channels
1996 · Carmen Valenzuela, Eva Delpo´n, et al. · Circulation · 94
Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels
2008 · Eva Cuypers, Yousra Abdel-Mottaleb, et al. · Toxicon · 91
Gating of Shaker-type Channels Requires the Flexibility of S6 Caused by Prolines
2003 · Alain J. Labro, Adam L. Raes, et al. · Journal of Biological Chemistry · 86
Effects of antiarrhythmic drugs on cloned cardiac voltage-gated potassium channels expressed in Xenopus oocytes
2000 · Sascha Rolf, Wilhelm Haverkamp, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 82
Molecular Determinants of Stereoselective Bupivacaine Block of hKv1.5 Channels
1997 · Laura Franqueza, Mónica Longobardo, et al. · Circulation Research · 81
Works count: 167
Citation count: 6,367
H-index: 44
I10-index: 89
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