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Reinis R. Ruza

Observed names: R. Reinholds Ruza, R.R. Ruza, Reinis R Ruza, Reinis Reinholds Ruza, Reinis Ruza, Ruza, Reinis Reinholds
ORCID: 0000-0002-0509-3512
Observed ORCID: 0000-0002-0509-3512
OpenAlex ID: A5072279625
Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2
2020 · Jiandong Huo, Audrey Le Bas, et al. · Nature Structural & Molecular Biology · 483
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Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike
2020 · Jiandong Huo, Yuguang Zhao, et al. · Cell Host & Microbe · 317
Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient
2020 · Daming Zhou, Helen M. E. Duyvesteyn, et al. · Nature Structural & Molecular Biology · 264
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Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike
2020 · Jiandong Huo, Yuguang Zhao, et al. · Cell Host & Microbe · 83
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Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels
2018 · Zaineb Fourati, Rebecca J. Howard, et al. · Cell Reports · 34
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Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen
2019 · Benjamin N. Atkinson, David Steadman, et al. · MedChemComm · 27
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5‑Phenyl-1,3,4-oxadiazol-2(3 H )‑ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit
2020 · William Mahy, Nicky J. Willis, et al. · Journal of Medicinal Chemistry · 22
Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Closed State
2016 · Zaineb Fourati, Reinis Reinholds Ruza, et al. · Journal of Biological Chemistry · 21
Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines as Inhibitors of Notum Carboxylesterase Activity
2020 · William Mahy, Mikesh Patel, et al. · Journal of Medicinal Chemistry · 20
Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit
2022 · Nicky J. Willis, William Mahy, et al. · Journal of Medicinal Chemistry · 18
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The SARS-CoV-2 Spike Harbours a Lipid Binding Pocket Which Modulates Stability of the Prefusion Trimer
2020 · Loic Carrique, Helen ME Duyvesteyn, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 18
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Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike
2020 · Jiandong Huo, Yuguang Zhao, et al. · SSRN Electronic Journal · 17
Structural insights into Frizzled3 through nanobody modulators
2024 · James Hillier, Yuguang Zhao, et al. · Nature Communications · 16
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Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2
2021 · Jiandong Huo, Audrey Le Bas, et al. · Nature Structural & Molecular Biology · 14
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Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2
2020 · Jiangdong Huo, Audrey Le Bas, et al. · Nature Structural & Molecular Biology · 10
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Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike
2020 · Jiandong Huo, Yuguang Zhao, et al. · SSRN Electronic Journal · 7
Structural Analysis and Development of Notum Fragment Screening Hits
2022 · Yuguang Zhao, William Mahy, et al. · ACS Chemical Neuroscience · 6
A pivot-tether model for nucleosome recognition by the chromosomal passenger complex
2025 · Reinis R Ruza, Chyi Wei Chung, et al. · EMBO Reports · 3
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Structure of the SARS-CoV-2 spike S1 protein in complex with CR3022 Fab
2020 · J. Huo, Y. Zhao, et al. · Worldwide Protein Data Bank · 2
Structural Details of an Allosteric Mechanism for Bimodal Anesthetic Modulation of Pentameric Ligand-Gated Ion Channels
2018 · Rebecca J. Howard, Zaineb Fourati, et al. · Biophysical Journal · 1
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Structural analysis of Wnt signalling pathways
2021 · Ruza, Reinis Reinholds · Oxford University Research Archive (ORA) (University of Oxford)
Structure of the prefusion SARS-CoV-2 spike glycoprotein
2020 · H.M.E. Duyvesteyn, J. Ren, et al. · Worldwide Protein Data Bank
Structure of Notum in complex with a 1-(3-Chlorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid inhibitor
2020 · L. Vecchia, E.Y. Jones, et al. · Worldwide Protein Data Bank
Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Shut State
2017 · Zeineb Fourati, Reinis R. Ruza, et al. · Biophysical Journal
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X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with thiopental
2016 · Z. Fourati, R.R. Ruza, et al. · Worldwide Protein Data Bank
Works count: 33
Citation count: 1,383
H-index: 14
I10-index: 15
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