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Shuo‐Chien Ling

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
2021 · Daniel J. Klionsky, Amal Kamal Abdel-Aziz, et al. · Autophagy · 2,608
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Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
2013 · Shuo-Chien Ling, Magdalini Polymenidou, et al. · Neuron · 1,806
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Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
2011 · Magdalini Polymenidou, Clotilde Lagier-Tourenne, et al. · Nature Neuroscience · 1,332
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
2012 · Clotilde Lagier-Tourenne, Magdalini Polymenidou, et al. · Nature Neuroscience · 739
Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration
2013 · Clotilde Lagier-Tourenne, Michael Baughn, et al. · Proceedings of the National Academy of Sciences · 561
Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs
2016 · Jie Jiang, Qiang Zhu, et al. · Neuron · 536
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ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
2013 · Eveline S. Arnold, Shuo-Chien Ling, et al. · Proceedings of the National Academy of Sciences · 492
ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS
2010 · Shuo-Chien Ling, Claudio P. Albuquerque, et al. · Proceedings of the National Academy of Sciences · 449
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ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS
2018 · Jone López-Erauskin, Takahiro Tadokoro, et al. · Neuron · 233
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ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP
2015 · Shuying Sun, Shuo-Chien Ling, et al. · Nature Communications · 229
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Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS
2015 · Shuying Sun, Ying Sun, et al. · Proceedings of the National Academy of Sciences · 196
Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein
2004 · Shuo-Chien Ling, Peter S. Fahrner, et al. · Proceedings of the National Academy of Sciences · 170
Muscle Expression of Mutant Androgen Receptor Accounts for Systemic and Motor Neuron Disease Phenotypes in Spinal and Bulbar Muscular Atrophy
2014 · Constanza J. Cortes, Shuo-Chien Ling, et al. · Neuron · 166
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Microtubule binding by dynactin is required for microtubule organization but not cargo transport
2007 · Hwajin Kim, Shuo-Chien Ling, et al. · The Journal of Cell Biology · 133
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Fused in Sarcoma (FUS) Protein Lacking Nuclear Localization Signal (NLS) and Major RNA Binding Motifs Triggers Proteinopathy and Severe Motor Phenotype in Transgenic Mice
2013 · Tatyana A. Shelkovnikova, Owen M. Peters, et al. · Journal of Biological Chemistry · 126
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Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS
2015 · Jacqueline C Mitchell, Remy Constable, et al. · Acta Neuropathologica Communications · 117
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A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery
2022 · Hayden Weng Siong Tan, Guang Lu, et al. · Nature Communications · 111
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
2021 · Klionsky, Daniel J, Abdel-Aziz, Amal Kamal, et al. · Research at the University of Copenhagen (University of Copenhagen) · 100
Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination
2018 · Jia Wang, Wan Yun Ho, et al. · Proceedings of the National Academy of Sciences · 87
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis
2019 · Shuo-Chien Ling, Somasish Ghosh Dastidar, et al. · eLife · 86
Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions
2018 · Shuo-Chien Ling · Neural Plasticity · 81
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A Receptor for Activated C Kinase Is Part of Messenger Ribonucleoprotein Complexes Associated with PolyA-mRNAs in Neurons
2002 · Frank Angenstein, Anne M. Evans, et al. · Journal of Neuroscience · 81
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Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction
2020 · Audrey Yi Tyan Peng, Ira Agrawal, et al. · Proceedings of the National Academy of Sciences · 75
The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy
2019 · Wan Yun Ho, Yee Kit Tai, et al. · Autophagy · 73
Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis
2017 · Dara Ditsworth, Marcus Maldonado, et al. · Acta Neuropathologica · 69
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Works count: 61
Citation count: 11,360
H-index: 34
I10-index: 46
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