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Ralph F. Hirschmann

A new class of angiotensin-converting enzyme inhibitors
1980 · A. A. Patchett, E. Harris, et al. · Nature · 698
A potent cyclic hexapeptide analogue of somatostatin
1981 · Daniel F. Veber, Roger M. Freidinger, et al. · Nature · 419
Peptide Synthesis Catalyzed by an Antibody Containing a Binding Site for Variable Amino Acids
1994 · Ralph Hirschmann, Amos B. Smith, et al. · Science · 354
Acetamidomethyl. A Novel Thiol Protecting Group for Cysteine
1972 · Daniel Veber, John Milkowski, et al. · Journal of the American Chemical Society · 324
De novo design and synthesis of somatostatin non-peptide peptidomimetics utilizing .beta.-D-glucose as a novel scaffolding
1993 · Ralph Hirschmann, K. C. Nicolaou, et al. · Journal of the American Chemical Society · 272
Nonpeptidal peptidomimetics with .beta.-D-glucose scaffolding. A partial somatostatin agonist bearing a close structural relationship to a potent, selective substance P antagonist
1992 · Ralph Hirschmann, K. C. Nicolaou, et al. · Journal of the American Chemical Society · 229
Medicinal Chemistry in the Golden Age of Biology: Lessons from Steroid and Peptide Research
1991 · Ralph Hirschmann · Angewandte Chemie International Edition in English · 227
A super active cyclic hexapeptide analog of somatostatin
1984 · Daniel F. Veber, Richard Saperstein, et al. · Life Sciences · 166
Conformationally restricted bicyclic analogs of somatostatin.
1978 · D F Veber, F W Holly, et al. · Proceedings of the National Academy of Sciences · 145
Design, synthesis, and crystal structure of a pyrrolinone-based peptidomimetic possessing the conformation of a .beta.-strand: potential application to the design of novel inhibitors of proteolytic enzymes
1992 · Amos B. Smith, Terence P. Keenan, et al. · Journal of the American Chemical Society · 137
Azide and Cyanide Displacements via Hypervalent Silicate Intermediates
1999 · Eric D. Soli, Amy S. Manoso, et al. · The Journal of Organic Chemistry · 135
Total synthesis of an enzyme. V. Preparation of enzymatically active material
1969 · Ralph Hirschmann, Ruth F. Nutt, et al. · Journal of the American Chemical Society · 135
De Novo Design, Synthesis, and X-ray Crystal Structures of Pyrrolinone-Based .beta.-Strand Peptidomimetics
1994 · Amos B. Smith, Mark C. Guzman, et al. · Journal of the American Chemical Society · 109
The Controlled Synthesis of Peptides in Aqueous Medium. I. The Use of α-Amino Acid N-Carboxyanhydrides
1966 · Robert G. Denkewalter, H. Schwam, et al. · Journal of the American Chemical Society · 108
Modulation of Receptor and Receptor Subtype Affinities Using Diastereomeric and Enantiomeric Monosaccharide Scaffolds as a Means to Structural and Biological Diversity. A New Route to Ether Synthesis
1998 · Ralph Hirschmann, John Hynes,, et al. · Journal of Medicinal Chemistry · 107
Controlled synthesis of peptides in aqueous medium. III. Use of Leuch's anhydrides in the synthesis of di-peptides. Mechanism and control of side reactions
1967 · Ralph F. Hirschmann, R G Strachan, et al. · The Journal of Organic Chemistry · 102
Pyrrolinone-Based Peptidomimetics.“Let the Enzyme or Receptor be the Judge”
2010 · Amos B. Smith, Adam K. Charnley, et al. · Accounts of Chemical Research · 97
The first design and synthesis of a steroidal peptidomimetic. The potential value of peptidomimetics in elucidating the bioactive conformation of peptide ligands
1992 · Ralph Hirschmann, Paul A. Sprengeler, et al. · Journal of the American Chemical Society · 89
Controlled synthesis of peptides in aqueous medium. VIII. Preparation and use of novel .alpha.-amino acid N-carboxyanhydrides
1971 · Ralph Hirschmann, Harvey Schwam, et al. · Journal of the American Chemical Society · 86
Design and synthesis of peptidomimetic inhibitors of HIV-1 protease and renin. Evidence for improved transport
1994 · Amos B. Smith, Ralph Hirschmann, et al. · Journal of Medicinal Chemistry · 85
Total synthesis of an enzyme. I. Objective and strategy
1969 · Robert G. Denkewalter, Daniel F. Veber, et al. · Journal of the American Chemical Society · 85
Inferences about the conformation of somatostatin at a biologic receptor based on NMR studies
1978 · Byron H. Arison, Ralph Hirschmann, et al. · Bioorganic Chemistry · 82
Phosphonate Diester and Phosphonamide Synthesis. Reaction Coordinate Analysis by 31P NMR Spectroscopy: Identification of Pyrophosphonate Anhydrides and Highly Reactive Phosphonylammonium Salts1
1997 · Ralph Hirschmann, Kraig M. Yager, et al. · Journal of the American Chemical Society · 76
Heterocyclic analogs of the antihypertensive .beta.-adrenergic blocking agent (S)-2-[3-(tert-butylamino)-2-hydroxypropoxy]-3-cyanopyridine
1980 · John J. Baldwin, Edward L. Engelhardt, et al. · Journal of Medicinal Chemistry · 76
The Rearrangement of the Steroid C/D Rings1
1954 · Ralph Hirschmann, C. Stewart Snoddy, et al. · Journal of the American Chemical Society · 74
Works count: 198
Citation count: 7,639
H-index: 47
I10-index: 120
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