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Paolo Ambrosino

Observed names: Ambrosino, Paolo, P. Ambrosino
ORCID: 0000-0002-7761-5551
Observed ORCID: 0000-0002-7761-5551
OpenAlex ID: A5072561516
Early-Onset Epileptic Encephalopathy Caused by Gain-of-Function Mutations in the Voltage Sensor of K v 7.2 and K v 7.3 Potassium Channel Subunits
2015 · Francesco Miceli, Maria Virginia Soldovieri, et al. · Journal of Neuroscience · 201
Genotype–phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of K v 7.2 potassium channel subunits
2013 · Francesco Miceli, Maria Virginia Soldovieri, et al. · Proceedings of the National Academy of Sciences · 192
Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide
2012 · Paolo Ambrosino, Maria Virginia Soldovieri, et al. · British Journal of Pharmacology · 146
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Effects of natural and synthetic isothiocyanate-based H 2 S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels
2017 · Lorenzo Di Cesare Mannelli, Elena Lucarini, et al. · Neuropharmacology · 118
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Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction
2020 · Piera Nappi, Francesco Miceli, et al. · Pflügers Archiv - European Journal of Physiology · 113
Characterization of two de novo KCNT1 mutations in children with malignant migrating partial seizures in infancy
2016 · Francesca Rizzo, Paolo Ambrosino, et al. · Molecular and Cellular Neuroscience · 110
Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain‐of‐function variant
2016 · John J. Millichap, Francesco Miceli, et al. · Epilepsia · 106
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The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of K v 7 channels
2014 · Fabio A. Iannotti, Cristoforo Silvestri, et al. · Proceedings of the National Academy of Sciences · 101
Novel KCNQ2 and KCNQ3 Mutations in a Large Cohort of Families with Benign Neonatal Epilepsy: First Evidence for an Altered Channel Regulation by Syntaxin-1A
2013 · Maria Virginia Soldovieri, Nadia Boutry-Kryza, et al. · Human Mutation · 101
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The Ever Changing Moods of Calmodulin: How Structural Plasticity Entails Transductional Adaptability
2014 · Alvaro Villarroel, Maurizio Taglialatela, et al. · Journal of Molecular Biology · 99
Early Treatment with Quinidine in 2 Patients with Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) Due to Gain-of-Function KCNT1 Mutations: Functional Studies, Clinical Responses, and Critical Issues for Personalized Therapy
2018 · Robertino Dilena, Jacopo C. DiFrancesco, et al. · Neurotherapeutics · 90
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Expression and function of Kv7.4 channels in rat cardiac mitochondria: possible targets for cardioprotection
2015 · Lara Testai, Vincenzo Barrese, et al. · Cardiovascular Research · 81
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Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate
2016 · Maria Virginia Soldovieri, Paolo Ambrosino, et al. · Scientific Reports · 52
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Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin
2015 · Paolo Ambrosino, Alessandro Alaimo, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 50
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Pharmacological Targeting of Neuronal Kv7.2/3 Channels: A Focus on Chemotypes and Receptor Sites
2017 · Francesco Miceli, Maria V. Soldovieri, et al. · Current Medicinal Chemistry · 49
De novo gain‐of‐function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy
2018 · Paolo Ambrosino, Maria Virginia Soldovieri, et al. · Annals of Neurology · 47
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators
2016 · Alessia Bertamino, Carmine Ostacolo, et al. · Journal of Medicinal Chemistry · 47
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism
2022 · Francesco Miceli, Charissa Millevert, et al. · EBioMedicine · 46
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A novel homozygous KCNQ3 loss‐of‐function variant causes non‐syndromic intellectual disability and neonatal‐onset pharmacodependent epilepsy
2019 · Anna Lauritano, Sebastien Moutton, et al. · Epilepsia Open · 46
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Identification of a Potent Tryptophan-Based TRPM8 Antagonist With in Vivo Analgesic Activity
2018 · Alessia Bertamino, Nunzio Iraci, et al. · Journal of Medicinal Chemistry · 46
Functional and biochemical interaction between PPARα receptors and TRPV1 channels: Potential role in PPARα agonists-mediated analgesia
2014 · Paolo Ambrosino, Maria Virginia Soldovieri, et al. · Pharmacological Research · 45
Neurounina-1, a Novel Compound That Increases Na+/Ca2+ Exchanger Activity, Effectively Protects against Stroke Damage
2012 · Pasquale Molinaro, Maria Cantile, et al. · Molecular Pharmacology · 44
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators
2019 · Carmine Ostacolo, Francesco Miceli, et al. · Journal of Medicinal Chemistry · 39
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Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy
2022 · Mario Nappi, Vincenzo Barrese, et al. · Proceedings of the National Academy of Sciences · 38
T-type channel blocking properties and antiabsence activity of two imidazo[1,2-b]pyridazine derivatives structurally related to indomethacin
2008 · Maria Grazia Rimoli, Emilio Russo, et al. · Neuropharmacology · 37
Works count: 64
Citation count: 2,597
H-index: 29
I10-index: 48
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