Author

Nuala McCabe

Observed names: McCabe, Nuala, N McCabe, N. MCCABE, N. McCabe, N. Mccabe

Observed institutions: Queen's University Belfast, Belfast Health and Social Care Trust, Institute of Cancer Research, National University of Singapore, Cancer Research UK, Belfast City Hospital, Duke-NUS Medical School, Almac (United Kingdom), National University Health System, Cancer Science Institute of Singapore

OpenAlex ID: A5072702884

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

2005 · Hannah Farmer, Nuala McCabe, et al. · Nature · 6,629

Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition

2006 · Nuala McCabe, Nicholas C. Turner, et al. · Cancer Research · 1,310

Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer

2016 · Eileen E. Parkes, Steven M. Walker, et al. · JNCI Journal of the National Cancer Institute · 460

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DNA Polymerases as Potential Therapeutic Targets for Cancers Deficient in the DNA Mismatch Repair Proteins MSH2 or MLH1

2010 · Sarah A. Martin, Nuala McCabe, et al. · Cancer Cell · 201

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Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer

2005 · A.N.J. TUTT, C.J. LORD, et al. · Cold Spring Harbor Symposia on Quantitative Biology · 195

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BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents

2001 · Paul B Mullan, Jennifer E Quinn, et al. · Oncogene · 154

BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of poly (ADP-ribose) polymerase: An issue of potency

2005 · Nuala McCabe, Christopher J. Lord, et al. · Cancer Biology & Therapy · 147

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Potentiation of Inflammatory CXCL8 Signalling Sustains Cell Survival in PTEN-deficient Prostate Carcinoma

2012 · Pamela J. Maxwell, Jonathan Coulter, et al. · European Urology · 82

Mechanistic Rationale to Target PTEN-Deficient Tumor Cells with Inhibitors of the DNA Damage Response Kinase ATM

2015 · Nuala McCabe, Conor Hanna, et al. · Cancer Research · 79

Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer

2009 · N McCabe, M A Cerone, et al. · Oncogene · 65

BRCA1 Regulates the Interferon γ-mediated Apoptotic Response

2002 · Heather N. Andrews, Paul B. Mullan, et al. · Journal of Biological Chemistry · 62

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miR-191 promotes radiation resistance of prostate cancer through interaction with RXRA

2019 · Jessica Ray, Charles Haughey, et al. · Cancer Letters · 54

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BRCA1 Interacts with and Is Required for Paclitaxel-Induced Activation of Mitogen-Activated Protein Kinase Kinase Kinase 3

2004 · Paula M. Gilmore, Nuala McCabe, et al. · Cancer Research · 45

A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer

2019 · Richard D. A. Wilkinson, Roberta E. Burden, et al. · Journal of Oncology · 31

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DNA Repair Deficiency in Breast Cancer: Opportunities for Immunotherapy

2019 · Elaine Gilmore, Nuala McCabe, et al. · Journal of Oncology · 31

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IGF-1R inhibition sensitizes breast cancer cells to ATM-related kinase (ATR) inhibitor and cisplatin

2016 · Ciara H. O’Flanagan, Sandra O’Shea, et al. · Oncotarget · 31

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Prior knowledge transfer across transcriptional data sets and technologies using compositional statistics yields new mislabelled ovarian cell line

2016 · Jaine K. Blayney, Timothy Davison, et al. · Nucleic Acids Research · 30

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Activation of MAPK signalling results in resistance to saracatinib (AZD0530) in ovarian cancer

2017 · Niamh McGivern, Aya El-Helali, et al. · Oncotarget · 27

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2018 · Joanna Stanicka, Leonie Rieger, et al. · Oncogene · 26

Defining the molecular evolution of extrauterine high grade serous carcinoma

2019 · James P. Beirne, Darragh G. McArt, et al. · Gynecologic Oncology · 21

Role played by BRCA1 in regulating the cellular response to stress

2001 · P.M. Gilmore, J.E. Quinn, et al. · Biochemical Society Transactions · 20

The role of PTEN as a cancer biomarker

2016 · Nuala McCabe, Kevin M. Prise, et al. · Oncoscience · 19

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Uncovering BRCA1-regulated signalling pathways by microarray-based expression profiling

2001 · P. B. Mullan, S. McWilliams, et al. · Biochemical Society Transactions · 18

Topoisomerase II inhibitors induce cGAS-STING dependent inflammation resulting in cytokine induction and immune checkpoint activation

2019 · R. D. A Wilkinson, N. McCabe, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 13

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X-Chromosome Inactivation: X Marks the Spot for BRCA1

2003 · Caroline Stone, Nuala McCabe, et al. · Current Biology · 11

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Works count: 81

Citation count: 9,807

H-index: 20

I10-index: 25