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Author

Tomas Šinkūnas

Observed names: Sinkunas, Tomas, T. Sinkunas, Tomas Sinkunas, Tomas Sinkūnas
Institution: Vilnius University
Observed institution: Vilnius University
ORCID: 0000-0001-6004-0897
Observed ORCID: 0000-0001-6004-0897
OpenAlex ID: A5072733063
Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes
2014 · Mark D. Szczelkun, Maria S. Tikhomirova, et al. · Proceedings of the National Academy of Sciences · 456
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Cas3 is a single‐stranded DNA nuclease and ATP‐dependent helicase in the CRISPR/Cas immune system
2011 · Tomas Sinkunas, Giedrius Gasiunas, et al. · The EMBO Journal · 452
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In vitro reconstitution of Cascade‐mediated CRISPR immunity in Streptococcus thermophilus
2013 · Tomas Sinkunas, Giedrius Gasiunas, et al. · The EMBO Journal · 228
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Directional R-Loop Formation by the CRISPR-Cas Surveillance Complex Cascade Provides Efficient Off-Target Site Rejection
2015 · Marius Rutkauskas, Tomas Sinkunas, et al. · Cell Reports · 164
Molecular mechanisms of CRISPR-mediated microbial immunity
2013 · Giedrius Gasiunas, Tomas Sinkunas, et al. · Cellular and Molecular Life Sciences · 124
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BREX system of Escherichia coli distinguishes self from non-self by methylation of a specific DNA site
2018 · Julia Gordeeva, Natalya Morozova, et al. · Nucleic Acids Research · 113
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DnaQ exonuclease‐like domain of Cas2 promotes spacer integration in a type I‐E CRISPR‐Cas system
2018 · Gediminas Drabavicius, Tomas Sinkunas, et al. · EMBO Reports · 39
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DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system
2020 · Donata Tuminauskaite, Danguole Norkunaite, et al. · BMC Biology · 36
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Innate programmable DNA binding by CRISPR-Cas12m effectors enable efficient base editing
2024 · Greta Bigelyte, Brigita Duchovska, et al. · Nucleic Acids Research · 23
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A quantitative model for the dynamics of target recognition and off-target rejection by the CRISPR-Cas Cascade complex
2022 · Marius Rutkauskas, Inga Songailiene, et al. · Nature Communications · 18
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The energy landscape for R-loop formation by the CRISPR–Cas Cascade complex
2023 · Dominik J. Kauert, Julene Madariaga-Marcos, et al. · Nature Structural & Molecular Biology · 12
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Dynamic interplay between target search and recognition for a Type I CRISPR-Cas system
2023 · Pierre Aldag, Marius Rutkauskas, et al. · Nature Communications · 12
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Decision-Making in Cascade Complexes Harboring crRNAs of Altered Length
2019 · Inga Songailiene, Marius Rutkauskas, et al. · Cell Reports · 12
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Disarming of type I-F CRISPR-Cas surveillance complex by anti-CRISPR proteins AcrIF6 and AcrIF9
2022 · Egle Kupcinskaite, Marijonas Tutkus, et al. · Scientific Reports · 9
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Cas3 Nuclease–Helicase Activity Assays
2015 · Tomas Sinkunas, Giedrius Gasiunas, et al. · Methods in molecular biology · 8
Off-target detection of CRISPR-Cas9 nuclease in vitro with CROFT-Seq
2026 · Paulius Toliusis, Algirdas Grybauskas, et al. · Synthetic Biology · 2
A DNA mimic jams the Cas9 scissors
2025 · Tomas Sinkunas, Giedre Tamulaitiene · FEBS Journal
Energy landscapes of CRISPR/Cas R-loop formation from ultrafast twist measurements
2022 · Julene Madariaga Marcos, Dominik J. Kauert, et al. · Biophysical Journal
Dissecting the Target Recognition by CRISPR/Cas Effector Complexes with Ultrafast Twist Measurements
2021 · Julene Madariaga Marcos, Dominik J. Kauert, et al. · Biophysical Journal
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Crystal structure of anti-CRISPR protein AcrIF9
2020 · G. Tamulaitiene, T. Sinkunas, et al. · Worldwide Protein Data Bank
Additional file 14 of DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system
2020 · Tuminauskaite, Donata, Danguole Norkunaite, et al. · Figshare
Additional file 1 of DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system
2020 · Tuminauskaite, Donata, Danguole Norkunaite, et al. · Figshare
Investigating and Modelling the Target Recognition Dynamics of the CRISPR-Cas Surveillance Complex Cascade
2018 · Marius Rutkauskas, Tomas Sinkūnas, et al. · Biophysical Journal
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Dynamic DNA Target Proofreading in a CRISPR-Cas System
2015 · Marius Rutkauskas, Tomas Sinkunas, et al. · Biophysical Journal
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I tipo CRISPR-Cas sistemos DNR interferencijos atkūrimas in vitro
2015 · Tomas Šinkūnas
Works count: 40
Citation count: 1,708
H-index: 12
I10-index: 13
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