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Wayne R. Danter

Observed names: W. R. Danter, W.R. Danter, WR Danter, Wayne Danter, Wayne R Danter
ORCID: 0000-0002-9297-4405
Observed ORCID: 0000-0002-9297-4405
OpenAlex ID: A5072758095
COTI-2, a novel small molecule that is active against multiple human cancer cell linesin vitroandin vivo
2016 · Kowthar Y. Salim, Saman Maleki Vareki, et al. · Oncotarget · 155
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Neural Network Prediction of Obstructive Sleep Apnea From Clinical Criteria
1999 · Simon D. Kirby, Wayne Danter, et al. · CHEST Journal · 100
Novel anti-cancer drug COTI-2 synergizes with therapeutic agents and does not induce resistance or exhibit cross-resistance in human cancer cell lines
2018 · Saman Maleki Vareki, Kowthar Y. Salim, et al. · PLoS ONE · 46
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DeepNEU: cellular reprogramming comes of age – a machine learning platform with application to rare diseases research
2019 · Wayne R. Danter · Orphanet Journal of Rare Diseases · 34
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Viral pandemic preparedness: A pluripotent stem cell-based machine-learning platform for simulating SARS-CoV-2 infection to enable drug discovery and repurposing
2020 · Sally Esmail, Wayne Danter · Stem Cells Translational Medicine · 29
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COTI-2, a new anticancer drug currently under clinical investigation, targets mutant p53 and negatively modulates the PI3K/AKT/mTOR pathway
2016 · K.Y. Salim, S. Maleki Vareki, et al. · European Journal of Cancer · 25
NEUBOrg: Artificially Induced Pluripotent Stem Cell-Derived Brain Organoid to Model and Study Genetics of Alzheimer’s Disease Progression
2021 · Sally Esmail, Wayne Danter · Frontiers in Aging Neuroscience · 22
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DeepNEU: Artificially Induced Stem Cell (aiPSC) and Differentiated Skeletal Muscle Cell (aiSkMC) Simulations of Infantile Onset POMPE Disease (IOPD) for Potential Biomarker Identification and Drug Discovery
2019 · Sally Esmail, Wayne R. Danter · Frontiers in Cell and Developmental Biology · 21
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Artificially Induced Pluripotent Stem Cell-Derived Whole-Brain Organoid for Modelling the Pathophysiology of Metachromatic Leukodystrophy and Drug Repurposing
2021 · Sally Esmail, Wayne R. Danter · Biomedicines · 16
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Tracing Alzheimer’s Genetic Footprints: A Pioneering Longitudinal Study Using Artificial Intelligence to Unravel Mutation- Driven Risks and Progression in Virtual Patients; Part 1 – The APOE genotypes
2024 · WR Danter · medRxiv · 6
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aiCRISPRL: An Artificial Intelligence Platform for Stem Cell and Organoid Simulation with Extensive Gene Editing Capabilities
2022 · WR Danter · bioRxiv (Cold Spring Harbor Laboratory) · 6
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Lung organoid simulations for modelling and predicting the effect of mutations on SARS-CoV-2 infectivity
2021 · Sally Esmail, Wayne R. Danter · Computational and Structural Biotechnology Journal · 6
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Advancing Drug Development with aiHumanoid Simulations: A Virtual Phase 1 Comparative Study of Standard Chemotherapy versus Standard Chemotherapy plus COTI-2 for Pancreatic Adenocarcinoma
2023 · WR Danter · medRxiv · 5
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Stem‐cell based, machine learning approach for optimizing natural killer cell‐based personalized immunotherapy for high‐grade ovarian cancer
2021 · Sally Esmail, Wayne R. Danter · FEBS Journal · 5
Correction: COTI-2, a novel small molecule that is active against multiple human cancer cell lines in vitro and in vivo
2017 · Kowthar Y. Salim, Saman Maleki Vareki, et al. · Oncotarget · 5
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Tracing Alzheimer's Genetic Footprints: A Pioneering Longitudinal Study Using Artificial Intelligence to Unravel Mutation-Driven Risks and Progression in Virtual Patients; Part 2 – The APP, PSEN1 and PSEN2 mutations
2024 · Wayne Danter · Research Square · 4
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HAI-VECT(SCD): AI-Humanoid Enabled Virtual Clinical Trial for Sickle Cell Disease
2023 · WR Danter · medRxiv · 4
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An aiHumanoid Simulation of Gram-Negative Sepsis: A Comprehensive Multi-Organoid Platform for Advanced Disease Modeling, Drug Discovery, and Personalized Medicine
2023 · Wayne R Danter · bioRxiv (Cold Spring Harbor Laboratory) · 4
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AI-Guided Discovery of Novel SARS-CoV-2 PLpro Inhibitors: Accelerating Antiviral Drug Development in the Fight Against COVID-19
2023 · Will Spagnoli, Wayne R Danter · bioRxiv (Cold Spring Harbor Laboratory) · 3
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aiHumanoid Simulations Uncover Dominant-Negative Effects in HNRNPH2-Related Neurodevelopmental Disorders
2024 · WR Danter · medRxiv · 2
Age-Dependent Effects of UV Exposure and Xeroderma Pigmentosum Group A on DNA Damage, Repair Mechanisms, Genomic Instability, Cancer Risk, and Neurological Disorders
2024 · WR Danter · medRxiv · 2
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Investigating Genetic and Familial Risks in Childhood ALL: A Longitudinal Virtual Study Using aiHumanoid Simulations of TEL-AML1 Gene Fusion
2024 · WR Danter · medRxiv · 2
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A novel artificial lung organoid for simulating a patient derived adenocarcinoma of lung for personalized oncology
2021 · Sally Esmail, Wayne R Danter · medRxiv · 2
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DeepNEU: a Machine Learning Stem Cell simulation platform for evaluating the impact of Loss of Function and Gain of Function mutations in the SARS-CoV-2 genome
2020 · Sally Esmail, Wayne R. Danter · 2
aiAtlas: High-Fidelity Cell Simulations of Genetic Perturbations in Rare Diseases and Cancers
2025 · Wayne R Danter · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Works count: 40
Citation count: 511
H-index: 9
I10-index: 9
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