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Neil Brewis
Observed names:
Brewis, Neil D.,
N. Brewis,
N. D. Brewis,
N.D. Brewis,
Neil D. BREWIS,
Neil D. Brewis
show all 6
Institution:
F-star (United Kingdom)
Observed institutions:
University of Dundee,
University of California San Diego,
MRC Protein Phosphorylation and Ubiquitylation Unit,
F-star (United Kingdom),
Marie Curie,
Medical Research Council
show all 6
ORCID:
0000-0002-8171-9222
Observed ORCID:
0000-0002-8171-9222
OpenAlex ID:
A5073012449
Protein serine/threonine phosphatases; an expanding family
1990
·
Patricia T.W. Cohen
, Neil D. Brewis
, et al.
·
FEBS Letters
·
225
PDF
PPX, a novel protein serine/threonine phosphatase localized to centrosomes.
1993
·
N.D. Brewis
, A.J. Street
, et al.
·
The EMBO Journal
·
221
PDF
Anti-serum albumin domain antibodies for extending the half-lives of short lived drugs
2008
·
L. J. Holt
, A. Basran
, et al.
·
Protein Engineering Design and Selection
·
193
Separation of PP2A Core Enzyme and Holoenzyme with Monoclonal Antibodies against the Regulatory A Subunit: Abundant Expression of Both Forms in Cells
1997
·
Elisabeth Kremmer
, Kim Ohst
, et al.
·
Molecular and Cellular Biology
·
174
Protein phosphatase 4 is an essential enzyme required for organisation of microtubules at centrosomes in Drosophila embryos
1998
·
Nicholas R. Helps
, Neil D. Brewis
, et al.
·
Journal of Cell Science
·
119
PDF
Human Domain Antibodies against Virulence Traits ofCandida albicansInhibit Fungus Adherence to Vaginal Epithelium and Protect against Experimental Vaginal Candidiasis
2006
·
Flavia De Bernardis
, Haiqun Liu
, et al.
·
The Journal of Infectious Diseases
·
114
FS118, a Bispecific Antibody Targeting LAG-3 and PD-L1, Enhances T-Cell Activation Resulting in Potent Antitumor Activity
2020
·
Matthew Kraman
, Mustapha Faroudi
, et al.
·
Clinical Cancer Research
·
112
Drosophila contains three genes that encode distinct isoforms of protein phosphatase 1
1990
·
Viktor DOMBRÁDI
, J. Myles AXTON
, et al.
·
European Journal of Biochemistry
·
91
The structure of protein phosphatase 2A is as highly conserved as that of protein phosphatase I
1990
·
Sara Orgad
, Neil D. Brewis
, et al.
·
FEBS Letters
·
76
PDF
Evaluation of VP22 Spread in Tissue Culture
2000
·
Neil Brewis
, Anne Phelan
, et al.
·
Journal of Virology
·
73
FS222, a CD137/PD-L1 Tetravalent Bispecific Antibody, Exhibits Low Toxicity and Antitumor Activity in Colorectal Cancer Models
2020
·
Matthew A. Lakins
, Alexander Koers
, et al.
·
Clinical Cancer Research
·
65
Three genes for protein phosphatase 1 map to different human chromosomes: Sequence, expression and gene localisation of protein serine/threonine phosphatase 1 beta (PPP1CB)
1994
·
Hazel M. Barker
, Neil D. Brewis
, et al.
·
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
·
62
CD137/OX40 Bispecific Antibody Induces Potent Antitumor Activity that Is Dependent on Target Coengagement
2020
·
Miguel Gaspar
, John Pravin
, et al.
·
Cancer Immunology Research
·
58
A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance
2022
·
Timothy A. Yap
, Patricia M. LoRusso
, et al.
·
Clinical Cancer Research
·
53
PDF
Increasing the Ratio of PP2A Core Enzyme to Holoenzyme Inhibits Tat-Stimulated HIV-1 Transcription and Virus Production
1997
·
Ralf Ruediger
, Neil Brewis
, et al.
·
Virology
·
49
PDF
Dilated cardiomyopathy in transgenic mice expressing a mutant A subunit of protein phosphatase 2A
2000
·
Neil Brewis
, Kim Ohst
, et al.
·
American Journal of Physiology-Heart and Circulatory Physiology
·
46
Protein phosphatase X has been highly conserved during mammalian evolution
1992
·
Neil D. Brewis
, Patricia T.W. Cohen
·
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
·
44
Particle assembly incorporating a VP22–BH3 fusion protein, facilitating intracellular delivery, regulated release, and apoptosis
2003
·
N.D. Brewis
, A. Phelan
, et al.
·
Molecular Therapy
·
28
VP22-mediated and light-activated delivery of an anti-c-raf1 antisense oligonucleotide improves its activity after intratumoral injection in nude mice
2003
·
David Zavaglia
, Nadia Normand
, et al.
·
Molecular Therapy
·
20
Abstract 2719: Dual blockade of PD-L1 and LAG-3 with FS118, a unique bispecific antibody, induces CD8+ T-cell activation and modulates the tumor microenvironment to promote antitumor immune responses
2018
·
Matthew Kraman
, Natalie Fosh
, et al.
·
Cancer Research
·
14
IFNγ Production by Functionally Reprogrammed Tregs Promotes Antitumor Efficacy of OX40/CD137 Bispecific Agonist Therapy
2024
·
Charlotte J. Imianowski
, Paula Kuo
, et al.
·
Cancer Research Communications
·
7
PDF
M9657 Is a Bispecific Tumor-Targeted Anti-CD137 Agonist That Induces MSLN-Dependent Antitumor Immunity without Liver Inflammation
2023
·
Chunxiao Xu
, Xueyuan Zhou
, et al.
·
Cancer Immunology Research
·
7
715 FS118, a tetravalent bispecific antibody targeting LAG-3 and PD-L1, induces LAG-3 shedding resulting in receptor downregulation by T cells via a novel mechanism of action
2020
·
Michelle Morrow
, Mustapha Faroudi
, et al.
·
Regular and Young Investigator Award Abstracts
·
4
Antibodies as drugs—a Keystone Symposia report
2022
·
Jennifer Cable
, Erica Ollmann Saphire
, et al.
·
Annals of the New York Academy of Sciences
·
3
PDF
VP22-Mediated Delivery of Oligonucleotides Into Cells
1999
·
Nadia Normand
, Hans van Leeuwen
, et al.
·
Nature Biotechnology
·
3
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Works count:
128
Citation count:
1,875
H-index:
19
I10-index:
20
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