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Christophe Simard

Molecular Genetics and Functional Anomalies in a Series of 248 Brugada Cases with 11 Mutations in the TRPM4 Channel
2013 · Hui Liu, Stéphanie Chatel, et al. · PLoS ONE · 169
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Flufenamic acid as an ion channel modulator
2013 · Romain Guinamard, Christophe Simard, et al. · Pharmacology & Therapeutics · 159
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The Non-selective Monovalent Cationic Channels TRPM4 and TRPM5
2010 · Romain Guinamard, Laurent Sallé, et al. · Advances in experimental medicine and biology · 102
Transient receptor potential melastatin 4 inhibitor 9‐phenanthrol abolishes arrhythmias induced by hypoxia and re‐oxygenation in mouse ventricle
2011 · Christophe Simard, Laurent Sallé, et al. · British Journal of Pharmacology · 97
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The TRPM4 non-selective cation channel contributes to the mammalian atrial action potential
2013 · Christophe Simard, Thomas Hof, et al. · Journal of Molecular and Cellular Cardiology · 96
Implication of the TRPM4 nonselective cation channel in mammalian sinus rhythm
2013 · Thomas Hof, Christophe Simard, et al. · Heart Rhythm · 94
TRPM4 in cardiac electrical activity
2015 · Romain Guinamard, Patrice Bouvagnet, et al. · Cardiovascular Research · 82
Epac activator critically regulates action potential duration by decreasing potassium current in rat adult ventricle
2013 · Fabien Brette, Erick Blandin, et al. · Journal of Molecular and Cellular Cardiology · 33
Argon Exposure Induces Postconditioning in Myocardial Ischemia–Reperfusion
2017 · Sandrine Lemoine, Katrien Blanchart, et al. · Journal of Cardiovascular Pharmacology and Therapeutics · 32
TRPM4 non-selective cation channel in human atrial fibroblast growth
2020 · Christophe Simard, Christophe Magaud, et al. · Pflügers Archiv - European Journal of Physiology · 23
Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity
2020 · Lionel Froux, Ahmad Elbahnsi, et al. · European Journal of Medicinal Chemistry · 19
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TRPM4 Participates in Aldosterone-Salt-Induced Electrical Atrial Remodeling in Mice
2021 · Christophe Simard, Virginie Ferchaud, et al. · Cells · 14
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Proarrhythmic Effects of Aldosterone During Myocardial Ischemia–Reperfusion
2014 · Joachim Alexandre, Paolo-Emilio Puddu, et al. · Journal of Cardiovascular Pharmacology · 13
Ion Channels in the Development and Remodeling of the Aortic Valve
2023 · Christophe Simard, Margaux Aize, et al. · International Journal of Molecular Sciences · 9
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TRPM4 Participates in Irradiation-Induced Aortic Valve Remodeling in Mice
2022 · Harlyne Mpweme Bangando, Christophe Simard, et al. · Cancers · 8
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PAR 1 contribution in acute electrophysiological properties of oral anticoagulants in rabbit pulmonary vein sleeve preparations
2018 · Jonaz Font, Mathilda Simeon, et al. · Fundamental and Clinical Pharmacology · 6
Targeted Radiation Exposure Induces Accelerated Aortic Valve Remodeling in ApoE−/− Mice
2023 · Guillaume Rucher, Kevin Prigent, et al. · Journal of Clinical Medicine · 5
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Contribution of the TRPM4 Channel to Osteogenic Differentiation of Human Aortic Valve Interstitial Cells
2025 · Margaux Aize, Arthur Boilève, et al. · Journal of the American Heart Association · 4
EPAC1 and 2 inhibit K+ currents via PLC/PKC and NOS/PKG pathways in rat ventricular cardiomyocytes
2024 · Arthur Boileve, Olivier Romito, et al. · American Journal of Physiology-Cell Physiology · 4
TRPM4 contribution in mouse uterine contractions
2023 · Alexandre Fouchet, Harlyne Mpweme Bangando, et al. · Reproduction · 4
Impact of loading, heart rate, and short episodes of ischaemia on myocardial stiffness assessed using shear wave elastography in an open-chest animal model
2025 · Eric Saloux, Christophe Simard, et al. · European Heart Journal - Imaging Methods and Practice · 3
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Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes
2025 · Arthur Boileve, Margaux Aize, et al. · The Journal of Physiology · 2
New insights in osteogenic differentiation of human valvular interstitial cells: Implication of Transient Receptor Potential Melastatin 4 (TRPM4)
2024 · Margaux Aize, Benoit D. Roussel, et al. · Archives of cardiovascular diseases · 2
Cardiac 2-D Shear Wave Imaging Using a New Dedicated Clinical Ultrasound System: A Phantom Study
2024 · Eric Saloux, Morgane Le Garrec, et al. · Ultrasound in Medicine & Biology · 2
Functional characterization of a TRPM4 cation channel on human aortic valve endothelial cells
2025 · Corentin Kerevel, Margaux Aize, et al. · Archives of cardiovascular diseases · 1
Works count: 43
Citation count: 990
H-index: 13
I10-index: 13
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