Author

Husam Hussein Nawafleh

Observed names: Husam Nawafleh, Hussam H. Nawafleh, Hussam Nawafleh

Institution: Gulf Medical University

Observed institution: Gulf Medical University

ORCID: 0000-0001-7195-5101

Observed ORCID: 0000-0001-7195-5101

OpenAlex ID: A5073082870

Role of Hypoxia-Mediated Autophagy in Tumor Cell Death and Survival

2021 · Rania F. Zaarour, Bilal Azakir, et al. · Cancers · 103

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Hypoxia increases mutational load of breast cancer cells through frameshift mutations

2020 · Goutham Hassan Venkatesh, Pamela Bravo, et al. · OncoImmunology · 33

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Tumor Hypoxia: A Key Determinant of Microenvironment Hostility and a Major Checkpoint during the Antitumor Response

2018 · Amirtharaj Francis, Goutham Hassan Venkatesh, et al. · Critical Reviews in Immunology · 30

Chronic hypoxia is associated with transcriptomic reprogramming and increased genomic instability in cancer cells

2023 · Raefa Abou Khouzam, Mohak Sharda, et al. · Frontiers in Cell and Developmental Biology · 17

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Waterpipe smoke condensate influences epithelial to mesenchymal transition and interferes with the cytotoxic immune response in non-small cell lung cancer cell lines

2021 · Rania Zaarour, Prathibha Prasad, et al. · Oncology Reports · 13

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p53 reactivating small molecule PRIMA‑1MET/APR‑246 regulates genomic instability in MDA‑MB‑231 cells

2022 · Francis Amirtharaj, Goutham Venkatesh, et al. · Oncology Reports · 11

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Genomic Analysis of Waterpipe Smoke-Induced Lung Tumor Autophagy and Plasticity

2022 · Rania Faouzi Zaarour, Mohak Sharda, et al. · International Journal of Molecular Sciences · 8

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Effect of Hypoxia on Siglec-7 and Siglec-9 Receptors and Sialoglycan Ligands and Impact of Their Targeting on NK Cell Cytotoxicity

2024 · Husam Nawafleh, Nagwa Zeinelabdin, et al. · Pharmaceuticals · 7

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Evofosfamide Enhances Sensitivity of Breast Cancer Cells to Apoptosis and Natural-Killer-Cell-Mediated Cytotoxicity Under Hypoxic Conditions

2025 · Shubhankar Das, Goutham Hassan Venkatesh, et al. · Cancers · 5

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Waterpipe Smoke Condensate Impairs p53 Nuclear Localization in Association with HIF-1α Stabilization

2026 · Husam Nawafleh, Jerome Thiery, et al. · International Journal of Molecular Sciences

Waterpipe smoke condensate activates autophagy in non-tumorigenic lung epithelial cells: Implications for inflammation and stemness

2026 · Rania F. Zaarour, Bilal Azakir, et al. · PLoS ONE

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Waterpipe smoke condensate activates autophagy in non-tumorigenic lung epithelial cells: implications for inflammation and stemness

2026 · Rania Zaarour, Bilal Azakir, et al. · Figshare

ITPP in early pancreatic zebrafish xenografts mildly impacts tumor cell death without interfering with vascular normalization

2026 · Raefa Abou Khouzam, Filipa Amorim, et al. · BMC Cancer

Abstract 5384: The hypoxia-alleviating agent ITPP restores vascular function in zebrafish xenografts of pancreatic cancer

2024 · Raefa Abou Khouzam, Filipa Amorim, et al. · Cancer Research

Abstract 2995: Autophagy as a key driver of waterpipe smoke-induced lung cancer cell plasticity and resistance

2022 · Rania F. Zaarour, Mohak Sharda, et al. · Cancer Research

Abstract 5679: Application of a hypoxia metric to investigate tumor mutational burden and cancer cell immunogenicity in vitro

2022 · Raefa Abou Khouzam, Nagwa Ahmed Zeinelabdin, et al. · Cancer Research

Works count: 16

Citation count: 227

H-index: 7

I10-index: 6