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Susovan Mohapatra

Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides
2017 · Naoki Iwamoto, David C D Butler, et al. · Nature Biotechnology · 397
Novel genomic island modifies DNA with 7-deazaguanine derivatives
2016 · Jennifer J. Thiaville, Stefanie M. Kellner, et al. · Proceedings of the National Academy of Sciences · 128
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Tyrosyl-DNA phosphodiesterase and the repair of 3′-phosphoglycolate-terminated DNA double-strand breaks
2009 · Tong Zhou, Konstantin Akopiants, et al. · DNA repair · 84
Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS
2022 · Pachamuthu Kandasamy, Yuanjing Liu, et al. · Nucleic Acids Research · 78
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Requirement for XLF/Cernunnos in alignment-based gap filling by DNA polymerases λ and μ for nonhomologous end joining in human whole-cell extracts
2009 · Konstantin Akopiants, Rui-Zhe Zhou, et al. · Nucleic Acids Research · 64
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Preclinical evaluation of WVE-004, an investigational stereopure oligonucleotide for the treatment of C9orf72-associated ALS or FTD
2022 · Yuanjing Liu, Amy Andreucci, et al. · Molecular Therapy — Nucleic Acids · 57
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Development of a sensitive trial-ready poly(GP) CSF biomarker assay for C9orf72 -associated frontotemporal dementia and amyotrophic lateral sclerosis
2022 · Katherine M Wilson, Eszter Katona, et al. · Journal of Neurology Neurosurgery & Psychiatry · 31
Restoration of G1 chemo/radioresistance and double-strand-break repair proficiency by wild-type but not endonuclease-deficient Artemis
2011 · Susovan Mohapatra, Misako Kawahara, et al. · Nucleic Acids Research · 27
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Trimming of damaged 3′ overhangs of DNA double-strand breaks by the Metnase and Artemis endonucleases
2013 · Susovan Mohapatra, Steven M. Yannone, et al. · DNA repair · 26
2022 White Paper on Recent Issues in Bioanalysis: Fda Draft Guidance on Immunogenicity Information in Prescription Drug Labeling, Lnp & Viral Vectors Therapeutics/Vaccines Immunogenicity, Prolongation Effect, Ada Affinity, Risk-Based Approaches, Ngs, Qpcr, Ddpcr Assays ( Part 3 – Recommendations on Gene Therapy, Cell Therapy, Vaccines Immunogenicity & Technologies; Immunogenicity & Risk Assessment of Biotherapeutics and Novel Modalities; NAb Assays Integrated Approach)
2023 · Luying Pan, Johanna Mora, et al. · Bioanalysis · 22
Tracking the processing of damaged DNA double-strand break ends by ligation-mediated PCR: increased persistence of 3′-phosphoglycolate termini in SCAN1 cells
2013 · Konstantin Akopiants, Susovan Mohapatra, et al. · Nucleic Acids Research · 14
2024 White Paper on Recent Issues in Bioanalysis: Three Way-Cross Validation; Urine Clinical Analysis; Automated Methods; Regulatory Queries on Plasma Protein Binding; Automated Biospecimen Management; ELN Migration; Ultra-Sensitivity Mass Spectrometry ( Part 1A – Recommendations on Advanced Strategies for Mass Spectrometry Assays, Chromatography, Sample Preparation and BMV/Regulated Bioanalysis Part 1B - Regulatory Agencies’ Inputs on Regulated Bioanalysis/BMV)
2025 · John Wojcik, Timothy Sikorski, et al. · Bioanalysis · 13
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WVE-004, an investigational stereopure antisense oligonucleotide for the treatment of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) (2302)
2021 · Yuanjing Liu, Amy Andreucci, et al. · Neurology · 9
2025 White Paper on Recent Issues in Bioanalysis: Redosing Patients with AAV Gene Therapy; CRS Immunogenicity Risk; Shedding Assays; NHP Studies Immunogenicity; CMC vs Bioanalytical Assays; Artificial Intelligence-Powered Genomic Pipelines for NGS ( PART 3A – Recommendations on Gene, Cell, and Vaccine Therapies Immunogenicity & Technologies; Biotherapeutics & Biosimilars Immunogenicity Assessment & Clinical Relevance PART 3B – Regulatory Agencies’ Input on Immunogenicity/Technologies of Biotherapeutics, Gene, Cell & Vaccine Therapies)
2025 · Omar Tounekti, Sophie Shubow, et al. · Bioanalysis · 5
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Immunogenicity Assays Used in Support of Marketing Applications of Oligonucleotide Therapeutics
2026 · Cecilia Arfvidsson, Lin-Zhi Chen, et al. · The AAPS Journal
WVE‐005, a stereopure antisense oligonucleotide for MAPT silencing in tauopathies
2022 · ElenaAbbie DaleMaguire, Lankai Guo, et al. · Alzheimer s & Dementia
O4‐05‐02: the Investigational Stereopure Antisense Oligonucleotide Wve‐3972‐01 Preferentially Reduces G4c2 Repeat‐containing C9orf72 Transcripts: a Potential Therapeutic Approach for the Treatment of Frontotemporal Dementia
2018 · Jean-Cosme Dodart, Yuanjing Liu, et al. · Alzheimer s & Dementia
Stereopure Antisense Oligonucleotides Preferentially Knockdown G4C2 Repeat-Containing C9ORF72 Transcripts: A Potential Therapeutic Approach for the Treatment of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) (N2.002)
2018 · Yuanjing Liu, Jean-Cosme Dodart, et al. · Neurology
Selectivity and Biodistribution of WVE-120101, a Potential Antisense Oligonucleotide Therapy for the Treatment of Huntington’s Disease (S56.001)
2017 · M Meena, Lori Zboray, et al. · Neurology
Artemis and Metnase Mediated Processing of 3΄-blocked Dna Lesions: Role in Radio/chemoresistance and Dna Repair
2012 · Mohapatra, Susovan · VCU Scholars Compass (Virginia Commonwealth University)
Works count: 20
Citation count: 955
H-index: 12
I10-index: 12
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