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Pedro Casado
Observed name:
P. Casado
Observed institutions:
Universidad de Oviedo,
Queen Mary University of London,
Spanish National Centre for Cardiovascular Research,
Barts Cancer Institute
ORCID:
0000-0002-4207-9349
Observed ORCID:
0000-0002-4207-9349
OpenAlex ID:
A5073371177
Cancer associated fibroblast FAK regulates malignant cell metabolism
2020
·
Fevzi Demircioglu
, Jun Wang
, et al.
·
Nature Communications
·
155
PDF
Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs
2021
·
Henry Gerdes
, Pedro Casado
, et al.
·
Nature Communications
·
133
PDF
Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility
2018
·
Ana Angulo-Urarte
, Pedro Casado
, et al.
·
Nature Communications
·
81
PDF
Factors Secreted by Cancer-Associated Fibroblasts that Sustain Cancer Stem Properties in Head and Neck Squamous Carcinoma Cells as Potential Therapeutic Targets
2018
·
Saúl Álvarez-Teijeiro
, Cristina García-Inclán
, et al.
·
Cancers
·
60
PDF
Bespoken Nanoceria: An Effective Treatment in Experimental Hepatocellular Carcinoma
2020
·
Guillermo Fernández‐Varo
, Meritxell Perramón
, et al.
·
Hepatology
·
58
PDF
A Self-validating Quantitative Mass Spectrometry Method for Assessing the Accuracy of High-content Phosphoproteomic Experiments
2010
·
Pedro Casado
, Pedro R. Cutillas
·
Molecular & Cellular Proteomics
·
55
PDF
Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells
2018
·
Pedro Casado
, Edmund H. Wilkes
, et al.
·
Leukemia
·
54
PDF
Vincristine regulates the phosphorylation of the antiapoptotic protein HSP27 in breast cancer cells
2006
·
Pedro Casado
, Pedro Zuazua-Villar
, et al.
·
Cancer Letters
·
46
Cerium Oxide Nanoparticles Protect against Oxidant Injury and Interfere with Oxidative Mediated Kinase Signaling in Human-Derived Hepatocytes
2019
·
Silvia Carvajal
, Meritxell Perramón
, et al.
·
International Journal of Molecular Sciences
·
42
PDF
A systematic molecular and pharmacologic evaluation of AKT inhibitors reveals new insight into their biological activity
2020
·
Eleftherios Kostaras
, Teresa Kaserer
, et al.
·
British Journal of Cancer
·
39
PDF
Environmental Stress Affects the Activity of Metabolic and Growth Factor Signaling Networks and Induces Autophagy Markers in MCF7 Breast Cancer Cells
2014
·
Pedro Casado
, Benoit Bilanges
, et al.
·
Molecular & Cellular Proteomics
·
37
PDF
Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans
2021
·
Angelica Gualtieri
, Nikolina Kyprianou
, et al.
·
Nature Communications
·
36
PDF
Impact of phosphoproteomics in the translation of kinase‐targeted therapies
2016
·
Pedro Casado
, Maruan Hijazi
, et al.
·
PROTEOMICS
·
35
Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes
2023
·
Pedro Casado
, Ana Rio-Machin
, et al.
·
Signal Transduction and Targeted Therapy
·
33
PDF
Oxidative stress downstream of mTORC1 but not AKT causes a proliferative defect in cancer cells resistant to PI3K inhibition
2016
·
M Dermit
, P Casado
, et al.
·
Oncogene
·
32
PDF
A TRAF2 binding independent region of TNFR2 is responsible for TRAF2 depletion and enhancement of cytotoxicity driven by TNFR1
2013
·
Lucía Cabal-Hierro
, Noelia Artime
, et al.
·
Oncotarget
·
28
PDF
CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia
2022
·
William Grey
, Ana Rio-Machin
, et al.
·
Science Translational Medicine
·
25
Kinase activity ranking using phosphoproteomics data (KARP) quantifies the contribution of protein kinases to the regulation of cell viability
2017
·
Edmund H. Wilkes
, Pedro Casado
, et al.
·
Molecular & Cellular Proteomics
·
25
Stearoyl-CoA desaturase inhibition is toxic to acute myeloid leukemia displaying high levels of the de novo fatty acid biosynthesis and desaturation
2024
·
Vilma Dembitz
, Hannah Lawson
, et al.
·
Leukemia
·
23
PDF
PARP-1 activation after oxidative insult promotes energy stress-dependent phosphorylation of YAP1 and reduces cell viability
2020
·
Sandra M. Martín-Guerrero
, Pedro Casado
, et al.
·
Biochemical Journal
·
21
PDF
Proteomic Characterization of Acute Myeloid Leukemia for Precision Medicine
2023
·
Pedro Casado
, Pedro R. Cutillas
·
Molecular & Cellular Proteomics
·
19
Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth
2021
·
Emma Newport
, Ana Rita Pedrosa
, et al.
·
The Journal of Pathology
·
19
Targeting the lysine-specific demethylase 1 rewires kinase networks and primes leukemia cells for kinase inhibitor treatment
2022
·
Federico Pedicona
, Pedro Casado
, et al.
·
Science Signaling
·
17
eEF2K Activity Determines Synergy to Cotreatment of Cancer Cells With PI3K and MEK Inhibitors
2022
·
Maruan Hijazi
, Pedro Casado
, et al.
·
Molecular & Cellular Proteomics
·
14
PDF
His452Tyr polymorphism in the human 5-HT2A receptor affects clozapine-induced signaling networks revealed by quantitative phosphoproteomics
2021
·
Sandra M. Martín-Guerrero
, Paula Alonso
, et al.
·
Biochemical Pharmacology
·
13
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Works count:
12
Citation count:
116
H-index:
6
I10-index:
4
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