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Bruno Gavillet

Cardiac Sodium Channel Na v 1.5 Is Regulated by a Multiprotein Complex Composed of Syntrophins and Dystrophin
2006 · Bruno Gavillet, Jean-Sébastien Rougier, et al. · Circulation Research · 256
Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP
2015 · Rajarshi Mukherjee, Olga A Mareninova, et al. · Gut · 237
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Cardiac Voltage-Gated Sodium Channel Na v 1.5 Is Regulated by Nedd4-2 Mediated Ubiquitination
2004 · Miguel X. van Bemmelen, Jean-Sébastien Rougier, et al. · Circulation Research · 237
Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins
2004 · Jean-Sébastien Rougier, Miguel X. van Bemmelen, et al. · American Journal of Physiology-Cell Physiology · 141
Kv4 Potassium Channels Form a Tripartite Complex With the Anchoring Protein SAP97 and CaMKII in Cardiac Myocytes
2009 · Saïd El-Haou, Elise Balse, et al. · Circulation Research · 96
Variable Nav1.5 Protein Expression from the Wild-Type Allele Correlates with the Penetrance of Cardiac Conduction Disease in the Scn5a+/− Mouse Model
2010 · Anne-Laure Leoni, Bruno Gavillet, et al. · PLoS ONE · 90
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Cardiac sodium channel Nav1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1
2006 · Thomas Jespersen, Bruno Gavillet, et al. · Biochemical and Biophysical Research Communications · 81
Peroxynitrite activates ERK via Raf-1 and MEK, independently from EGF receptor and p21 in H9C2 cardiomyocytes
2005 · B PESSE, S LEVRAND, et al. · Journal of Molecular and Cellular Cardiology · 68
Molecular and clinical determinants of drug-induced long QT syndrome: an iatrogenic channelopathy
2004 · H Abriel, B Gavillet, et al. · Swiss Medical Weekly · 57
The cyclophilin inhibitor alisporivir prevents hepatitis C virus–mediated mitochondrial dysfunction
2011 · Giovanni Quarato, Annamaria D'Aprile, et al. · Hepatology · 56
Aldosterone increases voltage-gated sodium current in ventricular myocytes
2006 · Christophe Boixel, Bruno Gavillet, et al. · American Journal of Physiology-Heart and Circulatory Physiology · 52
Long-Term Amiodarone Administration Remodels Expression of Ion Channel Transcripts in the Mouse Heart
2004 · Sabrina Le Bouter, Aziza El Harchi, et al. · Circulation · 50
Nedd4-2-dependent ubiquitylation and regulation of the cardiac potassium channel hERG1
2011 · Maxime Albesa, Liliana Sintra Grilo, et al. · Journal of Molecular and Cellular Cardiology · 39
Debio 0932, A New Oral Hsp90 Inhibitor, Alleviates Psoriasis in a Xenograft Transplantation Model
2014 · K Stenderup, C Rosada, et al. · Acta Dermato Venereologica · 38
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Pharmacologic Targeting or Genetic Deletion of Mitochondrial Cyclophilin D Protects from NSAID-Induced Small Intestinal Ulceration in Mice
2010 · Amanda LoGuidice, Veronica Ramirez-Alcantara, et al. · Toxicological Sciences · 28
Phase I Study of Androgen Deprivation Therapy in Combination with Anti–PD-1 in Melanoma Patients Pretreated with Anti–PD-1
2022 · Caroline Robert, Céleste Lebbé, et al. · Clinical Cancer Research · 26
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Proteasome inhibitor (MG132) rescues Nav1.5 protein content and the cardiac sodium current in dystrophin-deficient mdx5cv mice
2013 · Jean-Sébastien Rougier, Bruno Gavillet, et al. · Frontiers in Physiology · 24
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Exploratory window‐of‐opportunity trial to investigate the tumor pharmacokinetics/pharmacodynamics of the IAP antagonist Debio 1143 in patients with head and neck cancer
2021 · Carlos Gomez‐Roca, Caroline Even, et al. · Clinical and Translational Science · 23
Abstract 5001: Open-label, non-randomized, exploratory pre-operative window-of-opportunity trial to investigate the pharmacokinetics and pharmacodynamics of the smac mimetic Debio 1143 in patients with resectable squamous cell carcinoma of the head and neck
2019 · Carlos Gomez-Roca, Caroline Even, et al. · Cancer Research · 6
A dose-finding study of the SMAC mimetic Debio 1143 when given in combination with avelumab to patients with advanced solid malignancies.
2019 · Rosalyn A. Juergens, Quincy S. Chu, et al. · Journal of Clinical Oncology · 6
Abstract 4703: The inhibitor of apoptosis protein (IAP) antagonist Debio 1143 enhances the immune response to anti-PD1/L1 inhibitors in vitro and in vivo
2018 · Antoine Attinger, Bruno Gavillet, et al. · Cancer Research · 6
PV-0518: Phase 1 study of Debio 1143 in combination with Concurrent Chemo-Radiotherapy in LA-SCCHN
2016 · Y. Tao, C. Le Tourneau, et al. · Radiotherapy and Oncology · 5
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Abstract C2: Clinical safety, pharmacokinetics and early evidence of activity of the oral IAPs inhibitor Debio 1143 in combination with carboplatin and paclitaxel: a phase Ib study
2015 · Isabelle Ray-Coquard, Christophe Le Tourneau, et al. · Molecular Cancer Therapeutics · 2
Data from Phase I Study of Androgen Deprivation Therapy in Combination with Anti–PD-1 in Melanoma Patients Pretreated with Anti–PD-1
2023 · Caroline Robert, Céleste Lebbé, et al. · 1
Abstract 3443: The IAP antagonist xevinapant, in combination with high-dose cisplatin chemoradiotherapy, induces NF-kB and apoptotic pathway biomarkers in patients with high-risk locally advanced squamous cell carcinoma of the head and neck
2022 · Luke Piggott, Bruno Gavillet, et al. · Cancer Research · 1
Works count: 46
Citation count: 1,633
H-index: 18
I10-index: 18
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