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Huang Zeng
Institution:
Jiaying University
Observed institutions:
Sun Yat-sen University,
Jiaying University,
Guangzhou University
ORCID:
0000-0003-1079-5233
Observed ORCIDs:
0000-0003-1079-5233,
0009-0000-8283-1147
OpenAlex ID:
A5073471374
Natural phenylethanoid glycosides diuretics derived from Lagopsis supina: Biological activity, mechanism, molecular docking, and structure-activity relationship
2022
·
Li Yang
, Huang Zeng
, et al.
·
Bioorganic Chemistry
·
24
Revealing the Active Constituents and Mechanisms of Semiliquidambar cathayensis Chang Roots against Rheumatoid Arthritis through Network Pharmacology, Molecular Docking, and in Vivo Experiment
2022
·
Xiaoyi Xia
, Huang Zeng
, et al.
·
Chemistry & Biodiversity
·
21
Synthesis and Biological Evaluation of Oleanolic Acid Derivatives as Selective Vascular Endothelial Growth Factor Promoter i-Motif Ligands
2021
·
Huang Zeng
, Shuangshuang Kang
, et al.
·
International Journal of Molecular Sciences
·
16
PDF
Identification of N-(3-(methyl(3-(orotic amido)propyl)amino)propyl) oleanolamide as a novel topoisomerase I catalytic inhibitor by rational design, molecular dynamics simulation, and biological evaluation
2023
·
Huang Zeng
, Huasong Xie
, et al.
·
Bioorganic Chemistry
·
8
Transcriptional regulation of telomeric repeat-containing RNA by acridine derivatives
2021
·
Shuangshuang Kang
, Jiaojiao Cao
, et al.
·
RNA Biology
·
7
PDF
Synthesis and biological evaluation of phenanthridine derivatives as dual-target inhibitors of DNA topoisomerase IB (TOP1) and tyrosyl-DNA phosphodiesterase 1 (TDP1), and potential antitumor agents
2026
·
Jian-Mei Gao
, Huilong Xie
, et al.
·
European Journal of Medicinal Chemistry
·
4
Identification of FTY720 and COH29 as novel topoisomerase I catalytic inhibitors by experimental and computational studies
2024
·
Huang Zeng
, Shengyuan Zhang
, et al.
·
Bioorganic Chemistry
·
4
Dendropanax proteus root and its major bio-phytochemicals alleviate rheumatoid arthritis by inhibiting TLR4/CLEC1B/PI3K/Akt/NF-κB pathways: proteomics, metabolomics, collagen-induced arthritis rats, MH7A cells, molecular docking, and molecular dynamic simulation
2025
·
Li Yang
, Yating Yang
, et al.
·
Journal of Ethnopharmacology
·
3
Targeted liposome entrapped iridium(III) complexes significantly increase antitumor activity in vitro and in vivo
2026
·
Hua Nie
, Jinze Xiang
, et al.
·
European Journal of Medicinal Chemistry
·
1
Design, Synthesis and Biological Evaluation of 6H-Benzimidazo[1′,2′:1,2]pyrido[3,4- b ]indole Derivatives as TDP1 Inhibitors: Potent Synergistic Agents with Topotecan against Cervical Cancer
2026
·
Huang Zeng
, Bo Qiu
, et al.
·
Journal of Medicinal Chemistry
·
1
Targeted screening of phenylpropanoids from Dendropanax proteus for rheumatoid arthritis therapy and mechanistic insights
2026
·
Qihui Wang
, Xinlu Huangfu
, et al.
·
Bioorganic Chemistry
·
1
A novel dual-functional ligand targeting c-Myc and VEGF promoter G-quadruplexes for colorectal cancer therapy
2026
·
Jian-Mei Gao
, Wenbo Yan
, et al.
·
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
Integrating machine learning and deep learning with multiple molecular fingerprints for topoisomerase I inhibitor screening and lead identification
2026
·
Huang Zeng
, Xuerou Zheng
, et al.
·
Molecular Diversity
Discovery of a potent TDP1 inhibitor through machine learning-driven predictive modeling combined with structure-based virtual screening and experimental validation
2026
·
Huang Zeng
, Manyi Zhang
, et al.
·
RSC Advances
PDF
PEG chain length modulates hepatic targeting of GalNAc liposomes via ligand exposure and optimal glycocluster conformation
2025
·
Hua Nie
, Xiao-Min Liu
, et al.
·
Journal of Drug Delivery Science and Technology
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Works count:
15
Citation count:
90
H-index:
5
I10-index:
3
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