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Christine Akfur
Observed names:
C. Akfur,
Christine M. Akfur
Institution:
Swedish Defence Research Agency
Observed institution:
Swedish Defence Research Agency
ORCID:
0000-0001-9078-9225
Observed ORCID:
0000-0001-9078-9225
OpenAlex ID:
A5073563956
Structural Changes of Phenylalanine 338 and Histidine 447 Revealed by the Crystal Structures of Tabun-Inhibited Murine Acetylcholinesterase,
2005
·
Fredrik Ekström
, Christine Akfur
, et al.
·
Biochemistry
·
157
Polymorph‐ and Size‐Dependent Uptake and Toxicity of TiO2 Nanoparticles in Living Lung Epithelial Cells
2011
·
Per Ola Andersson
, Christian Lejon
, et al.
·
Small
·
134
Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: Structural basis for differences in the ability to reactivate tabun conjugates
2006
·
Fredrik Ekström
, Yuan-Ping Pang
, et al.
·
Biochemical Pharmacology
·
125
Human primary bronchial epithelial cells respond differently to titanium dioxide nanoparticles than the lung epithelial cell lines A549 and BEAS-2B
2011
·
Barbro Ekstrand-Hammarström
, Christine M. Akfur
, et al.
·
Nanotoxicology
·
87
Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6
2016
·
Anders Allgardsson
, Lotta Berg
, et al.
·
Proceedings of the National Academy of Sciences
·
62
Divergent Structure–Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors
2013
·
C. David Andersson
, Nina Forsgren
, et al.
·
Journal of Medicinal Chemistry
·
46
Catalytic-site conformational equilibrium in nerve-agent adducts of acetylcholinesterase: Possible implications for the HI-6 antidote substrate specificity
2013
·
Elisabet Artursson
, Per Ola Andersson
, et al.
·
Biochemical Pharmacology
·
39
8-Isoprostane is an early biomarker for oxidative stress in chlorine-induced acute lung injury
2017
·
Linda Elfsmark
, Lina Ågren
, et al.
·
Toxicology Letters
·
35
Reactivation of tabun-hAChE investigated by structurally analogous oximes and mutagenesis
2009
·
Elisabet Artursson
, Christine Akfur
, et al.
·
Toxicology
·
35
Benefits of statistical molecular design, covariance analysis, and reference models in QSAR: a case study on acetylcholinesterase
2014
·
C. David Andersson
, J. Mikael Hillgren
, et al.
·
Journal of Computer-Aided Molecular Design
·
25
PDF
Anti-inflammatory and anti-fibrotic treatment in a rodent model of acute lung injury induced by sulfur dioxide
2018
·
Elisabeth Wigenstam
, Linda Elfsmark
, et al.
·
Clinical Toxicology
·
20
N-acetyl cysteine protects against chlorine-induced tissue damage in an ex vivo model
2020
·
Lina Ågren
, Linda Elfsmark
, et al.
·
Toxicology Letters
·
14
Ammonia exposure by intratracheal instillation causes severe and deteriorating lung injury and vascular effects in mice
2022
·
Linda Elfsmark
, Lina Ågren
, et al.
·
Inhalation Toxicology
·
13
High concentrations of ammonia induced cytotoxicity and bronchoconstriction in a precision-cut lung slices rat model
2021
·
Lina Ågren
, Linda Elfsmark
, et al.
·
Toxicology Letters
·
13
Broad‐Spectrum Antidote Discovery by Untangling the Reactivation Mechanism of Nerve‐Agent‐Inhibited Acetylcholinesterase
2022
·
Cecilia Lindgren
, Nina Forsgren
, et al.
·
Chemistry - A European Journal
·
12
PDF
Comparisons of acute inflammatory responses of nose-only inhalation and intratracheal instillation of ammonia in rats
2019
·
Linda Elfsmark
, Lina Ågren
, et al.
·
Inhalation Toxicology
·
12
PDF
An Unusual Dimeric Inhibitor of Acetylcholinesterase: Cooperative Binding of Crystal Violet
2017
·
Anders Allgardsson
, C. David Andersson
, et al.
·
Molecules
·
7
PDF
In Situ Assembly of Choline Acetyltransferase Ligands by a Hydrothiolation Reaction Reveals Key Determinants for Inhibitor Design
2020
·
Daniel Wiktelius
, Anders Allgardsson
, et al.
·
Angewandte Chemie International Edition
·
4
Rücktitelbild: In Situ Assembly of Choline Acetyltransferase Ligands by a Hydrothiolation Reaction Reveals Key Determinants for Inhibitor Design (Angew. Chem. 2/2021)
2020
·
Daniel Wiktelius
, Anders Allgardsson
, et al.
·
Angewandte Chemie
Back Cover: In Situ Assembly of Choline Acetyltransferase Ligands by a Hydrothiolation Reaction Reveals Key Determinants for Inhibitor Design (Angew. Chem. Int. Ed. 2/2021)
2020
·
Daniel Wiktelius
, Anders Allgardsson
, et al.
·
Angewandte Chemie International Edition
In Situ Assembly of Choline Acetyltransferase Ligands by a Hydrothiolation Reaction Reveals Key Determinants for Inhibitor Design
2020
·
Daniel Wiktelius
, Anders Allgardsson
, et al.
·
Angewandte Chemie
Design of Broad Spectrum Antidotes
2018
·
Cecilia M. Lindgren
, Nina Forsgren
, et al.
·
MMSL
Crystal structure of Acetylcholinesterase in complex with Crystal Violet
2017
·
A. Allgardsson
, C.D. Andersson
, et al.
·
Worldwide Protein Data Bank
Design of Reactive Drugs : Structure and Mechanism of Novel Nerve Agent Antidotes
2017
·
Cecilia Lindgren
, Nina Forsgren
, et al.
Structure of a pre-reaction ternary complex between sarin- acetylcholinesterase and HI-6
2015
·
A. Allgardsson
, L. Berg
, et al.
·
Worldwide Protein Data Bank
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Works count:
38
Citation count:
842
H-index:
13
I10-index:
16
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