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Marcos Lorca

Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer’s disease
2020 · Julio Rodríguez-Lavado, Carlos Gallardo-Garrido, et al. · European Journal of Medicinal Chemistry · 34
Structure-Activity Relationships Based on 3D-QSAR CoMFA/CoMSIA and Design of Aryloxypropanol-Amine Agonists with Selectivity for the Human β3-Adrenergic Receptor and Anti-Obesity and Anti-Diabetic Profiles
2018 · Marcos Lorca, Cesar Morales-Verdejo, et al. · Molecules · 27
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Combined CoMFA and CoMSIA 3D-QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor
2017 · Javier Romero-Parra, Hery Chung, et al. · European Journal of Pharmaceutical Sciences · 24
Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid Ligands
2019 · Marcos Lorca, Yudisladys Valdes, et al. · International Journal of Molecular Sciences · 16
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2D/3D-QSAR Model Development Based on a Quinoline Pharmacophoric Core for the Inhibition of Plasmodium falciparum: An In Silico Approach with Experimental Validation
2024 · Marcos Lorca, Gisela C. Muscia, et al. · Pharmaceuticals · 10
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Cancer and brassinosteroids: Mechanisms of action, SAR and future perspectives
2022 · Marcos Lorca, David Cabezas, et al. · Steroids · 9
Past and Present of the Antioxidant Studies in Chile: A Bibliometric Study from 2000 to 2024
2025 · Marcos Lorca, Alejandro Vega-Muñoz, et al. · Antioxidants · 4
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New Morphiceptin Peptidomimetic Incorporating (1S,2R,3S,4S,5R)-2-Amino-3,4,5-trihydroxycyclopen-tane-1-carboxylic acid: Synthesis and Structural Study
2020 · Raquel Soengas, Marcos Lorca, et al. · Molecules · 4
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Synthesis of Novel Nicotinic Ligands with Multimodal Action: Targeting Acetylcholine α4β2, Dopamine and Serotonin Transporters
2019 · Juan Pablo González-Gutiérrez, Hernán Armando Pessoa-Mahana, et al. · Molecules · 4
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Enterovirus en aguas naturales de Valparaíso: una propuesta metodológica para su análisis
2009 · Maritza Soler, Soledad Lobos, et al. · Revista de biología marina y oceanografía · 4
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3D-QSAR study for the development of chalcone-based inhibitors targeting ovarian cancer cells with experimental validation
2026 · Manuel Valenzuela-Valderrama, Aranxa Varas, et al. · Frontiers in Pharmacology · 3
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Design of Hybrid Quinoline–Chalcone Compounds Against Leishmania amazonensis Based on Computational Techniques: 2D- and 3D-QSAR with Experimental Validation
2025 · Marcos Lorca, Gisela C. Muscia, et al. · Pharmaceuticals · 2
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Design of benzimidazoles, benzoxazoles, benzothiazoles and thiazolopyridines as leukotriene A4 hydrolase inhibitors through 3D-QSAR, docking and molecular dynamics
2022 · Marcos Lorca, Mario Faúndez, et al. · Journal of the Serbian Chemical Society · 2
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Integrated computational modeling of chalcone-based inhibitors targeting carbonic anhydrase I and II: 3D-QSAR, molecular docking, and dynamics simulations
2026 · Mauricio Soto, David Cabezas, et al. · Journal of Computer-Aided Molecular Design · 1
Structure-Guided Discovery of Benzoic-Acid-Based TRPC6 Ligands: An Integrated Docking, MD, and MM-GBSA SAR Study: Potential Therapeutic Molecules for Autism Spectrum Disorder
2025 · Nicolás Ignacio Silva, Gianfranco Sabadini, et al. · Pharmaceuticals · 1
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Benzo[d]imidazole–Naphthalen-Arylmethanone Regioisomers as CB1 Ligands: Evaluation of Agonism via an Indirect Cytotoxicity-Based Approach
2025 · Analia Young Hwa Cho, Renato Burgos Ravanal, et al. · International Journal of Molecular Sciences
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Works count: 16
Citation count: 145
H-index: 6
I10-index: 5
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