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Author

Florence J. Hardy

Observed name: Florence Hardy
ORCID: 0000-0003-0671-0209
Observed ORCID: 0000-0003-0671-0209
OpenAlex ID: A5074254221
Directed evolution of an efficient and thermostable PET depolymerase
2022 · Elizabeth L. Bell, Ross Smithson, et al. · Nature Catalysis · 504
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Noncanonical Amino Acids in Biocatalysis
2024 · Zachary Birch-Price, Florence J. Hardy, et al. · Chemical Reviews · 122
Building Enzymes through Design and Evolution
2023 · Euan J. Hossack, Florence J. Hardy, et al. · ACS Catalysis · 102
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Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate
2017 · Zhihong Zhang, Tristan J. Smart, et al. · Proceedings of the National Academy of Sciences · 73
Efficient and selective energy transfer photoenzymes powered by visible light
2025 · Rebecca Crawshaw, Ross Smithson, et al. · Nature Chemistry · 56
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A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme
2024 · Amy E. Hutton, Jake Foster, et al. · Nature Communications · 46
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Mapping the Initial Stages of a Protective Pathway that Enhances Catalytic Turnover by a Lytic Polysaccharide Monooxygenase
2023 · Jingming Zhao, Ying Zhuo, et al. · Journal of the American Chemical Society · 35
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Engineered enzymes for enantioselective nucleophilic aromatic substitutions
2025 · Thomas M. Lister, George W. Roberts, et al. · Nature · 25
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A Noncanonical Tryptophan Analogue Reveals an Active Site Hydrogen Bond Controlling Ferryl Reactivity in a Heme Peroxidase
2021 · Mary Ortmayer, Florence J. Hardy, et al. · JACS Au · 22
Probing Ferryl Reactivity in a Nonheme Iron Oxygenase Using an Expanded Genetic Code
2024 · Florence J. Hardy, Matthew G. Quesne, et al. · ACS Catalysis · 14
Engineering mutually orthogonal PylRS / tRNA pairs for dual encoding of functional histidine analogues
2023 · Christopher J. Taylor, Florence J. Hardy, et al. · Protein Science · 12
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Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]‐Cycloadditions
2025 · Chuanjie Sun, Anna R. Kohn, et al. · Angewandte Chemie International Edition · 11
Atomic functional site scaffolding in biopolymers with RFdiffusion3
2026 · Jasper Butcher, Rohith Krishna, et al. · Science · 5
Recent Advances in Understanding, Enhancing and Creating Heme Peroxidases
2020 · Florence J. Hardy, Mary Ortmayer, et al. · Elsevier eBooks · 4
From First Principles to Function: How AI Is Reshaping Enzyme Design
2026 · Sebastian Lindner, Florence J. Hardy, et al. · Biochemistry · 1
Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]‐Cycloadditions
2025 · Chuanjie Sun, Anna R. Kohn, et al. · Angewandte Chemie · 1
Design of enantioselective photoenzymes by scaffolding mirror image catalytic sites
2026 · Florence J. Hardy, Rebecca Crawshaw, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Works count: 17
Citation count: 1,033
H-index: 11
I10-index: 12
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