Author

Oliver D.K. Maddocks

Observed names: Maddocks, Oliver, Maddocks, Oliver D. K., Maddocks, Oliver DK, Maddocks, Oliver David Kenneth, O. Maddocks, O.D.K. Maddocks, Oliver D.K. Maddocks, Oliver D K Maddocks, Oliver D. K. Maddocks, Oliver DK Maddocks, Oliver David Kenneth Maddocks, Oliver David Kenneth. Maddocks, Oliver Dk Maddocks, Oliver Maddocks, Oliver D.K. Maddocks

Institution: University of Glasgow

Observed institutions: University of Maryland, Baltimore, University of Helsinki, King's College London, Western General Hospital, Helsinki University Hospital, Cancer Research UK, Institute for Molecular Medicine Finland, Cancer Research UK Scotland Institute, Institute of Genetics and Cancer, University of Glasgow, University of Birmingham, University of Edinburgh

ORCID: 0000-0002-5551-9091

Observed ORCID: 0000-0002-5551-9091

OpenAlex ID: A5074382164

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells

2012 · Oliver D. K. Maddocks, Celia R. Berkers, et al. · Nature · 1,002

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

2012 · Barbara Chaneton, Petra Hillmann, et al. · Nature · 660

A roadmap for interpreting 13C metabolite labeling patterns from cells

2015 · Joerg M Buescher, Maciek R Antoniewicz, et al. · Current Opinion in Biotechnology · 629

Modulating the therapeutic response of tumours to dietary serine and glycine starvation

2017 · Oliver D. K. Maddocks, Dimitris Athineos, et al. · Nature · 600

Serine, but Not Glycine, Supports One-Carbon Metabolism and Proliferation of Cancer Cells

2014 · Christiaan F. Labuschagne, Niels J.F. van den Broek, et al. · Cell Reports · 572

One-carbon metabolism in cancer

2017 · Alice C Newman, Oliver D K Maddocks · British Journal of Cancer · 502

Metabolic Regulation by p53 Family Members

2013 · Celia R. Berkers, Oliver D.K. Maddocks, et al. · Cell Metabolism · 446

Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells

2016 · Oliver D.K. Maddocks, Christiaan F. Labuschagne, et al. · Molecular Cell · 440

Metabolic regulation by p53

2011 · Oliver D. K. Maddocks, Karen H. Vousden · Journal of Molecular Medicine · 355

Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy

2021 · Mylène Tajan, Marc Hennequart, et al. · Nature Communications · 304

Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

2016 · Bernadette Carroll, Dorothea Maetzel, et al. · eLife · 188

Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing

2017 · Bernadette Carroll, Glyn Nelson, et al. · The Journal of Cell Biology · 187

The creatine–phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis

2020 · Vassilis Papalazarou, Tong Zhang, et al. · Nature Metabolism · 183

Serine one-carbon catabolism with formate overflow

2016 · Johannes Meiser, Sergey Tumanov, et al. · Science Advances · 173

Serine and Functional Metabolites in Cancer

2017 · Alice C. Newman, Oliver D.K. Maddocks · Trends in Cell Biology · 167

Attaching and Effacing Escherichia coli Downregulate DNA Mismatch Repair Protein In Vitro and Are Associated with Colorectal Adenocarcinomas in Humans

2009 · Oliver D. K. Maddocks, Abigail J. Short, et al. · PLoS ONE · 148

Metabolic cross-feeding in imbalanced diets allows gut microbes to improve reproduction and alter host behaviour

2020 · Sílvia F. Henriques, Darshan B. Dhakan, et al. · Nature Communications · 144

An Escherichia coli Effector Protein Promotes Host Mutation via Depletion of DNA Mismatch Repair Proteins

2013 · Oliver David Kenneth Maddocks, Karen Mary Scanlon, et al. · mBio · 114

Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells

2021 · Alice Clare Newman, Mattia Falcone, et al. · Molecular Cell · 110

A Neuronal Relay Mediates a Nutrient Responsive Gut/Fat Body Axis Regulating Energy Homeostasis in Adult Drosophila

2018 · Alessandro Scopelliti, Christin Bauer, et al. · Cell Metabolism · 105

SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis

2022 · Erica Pranzini, Elisa Pardella, et al. · Cell Reports · 103

Autophagy promotes cell survival by maintaining NAD levels

2022 · Tetsushi Kataura, Lucia Sedlackova, et al. · Developmental Cell · 78

Sensitisation of cancer cells to radiotherapy by serine and glycine starvation

2022 · Mattia Falcone, Alejandro Huerta Uribe, et al. · British Journal of Cancer · 61

Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target

2023 · Johan Vande Voorde, Rory T. Steven, et al. · Nature Metabolism · 60

Polyamine pathway activity promotes cysteine essentiality in cancer cells

2020 · Tong Zhang, Christin Bauer, et al. · Nature Metabolism · 58

Works count: 151

Citation count: 8,077

H-index: 34

I10-index: 42