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Karlheinz Baumann

Observed names: Baumann Karlheinz, Baumann, K., Baumann, Karlheinz, K Baumann, K. Baumann, K.-H. Baumann, K.H Baumann, Karl-Heinz Baumann
Observed institutions: F. Hoffmann-La Roche AG, Novartis (Switzerland), Boston Children's Hospital, Harvard University, Center for Integrated Protein Science Munich, Deutsches Elektronen-Synchrotron DESY, LMU Klinikum, Technische Universität Darmstadt, Max Planck Institute for Medical Research, Roche (France), Max Planck Institute for Biophysical Chemistry, Max Planck Unit for Structural Molecular Biology, Sandoz Group AG (Switzerland), Adolf-Butenandt-Institut für Physiologische Chemie, Physikalische Biochemie und Zellbiologie, Bayer (Germany), Ludwig-Maximilians-Universität München
OpenAlex ID: A5074411763
Abnormal Alzheimer‐like phosphorylation of tau‐protein by cyclin‐dependent kinases cdk2 and cdk5
1993 · K. Baumann, E.-M. Mandelkow, et al. · FEBS Letters · 478
Gantenerumab: A Novel Human Anti-Aβ Antibody Demonstrates Sustained Cerebral Amyloid-β Binding and Elicits Cell-Mediated Removal of Human Amyloid-β
2012 · Bernd Bohrmann, Karlheinz Baumann, et al. · Journal of Alzheimer s Disease · 445
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Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules.
1995 · B Trinczek, J Biernat, et al. · Molecular Biology of the Cell · 340
The Endogenous and Cell Cycle-dependent Phosphorylation of tau Protein in Living Cells: Implications for Alzheimer’s Disease
1998 · Susanne Illenberger, Qingyi Zheng-Fischhöfer, et al. · Molecular Biology of the Cell · 304
Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases
2021 · Xianyuan Xiang, Karin Wind, et al. · Science Translational Medicine · 265
Curcumin‐Derived Pyrazoles and Isoxazoles: Swiss Army Knives or Blunt Tools for Alzheimer's Disease?
2007 · Rajeshwar Narlawar, Marcus Pickhardt, et al. · ChemMedChem · 174
Generation of Aβ38 and Aβ42 Is Independently and Differentially Affected by Familial Alzheimer Disease-associated Presenilin Mutations and γ-Secretase Modulation
2007 · Richard M. Page, Karlheinz Baumann, et al. · Journal of Biological Chemistry · 165
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Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcmeurin and phosphatase‐2A
1993 · G. Drewes, E.-M. Mandelkow, et al. · FEBS Letters · 154
Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study
2016 · Matthias Brendel, Federico Probst, et al. · Journal of Nuclear Medicine · 145
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Neuronal Localization of Presenilin-1 and Association with Amyloid Plaques and Neurofibrillary Tangles in Alzheimer’s Disease
1997 · Jorge Busciglio, Henrike Hartmann, et al. · Journal of Neuroscience · 90
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Novel γ-Secretase Enzyme Modulators Directly Target Presenilin Protein
2011 · Amelie Ebke, Thomas Luebbers, et al. · Journal of Biological Chemistry · 88
Longitudinal Assessment of Cerebral β-Amyloid Deposition in Mice Overexpressing Swedish Mutant β-Amyloid Precursor Protein Using 18F-Florbetaben PET
2013 · Axel Rominger, Matthias Brendel, et al. · Journal of Nuclear Medicine · 85
Independent Generation of Aβ42 and Aβ38 Peptide Species by γ-Secretase
2008 · Eva Czirr, Barbara A. Cottrell, et al. · Journal of Biological Chemistry · 72
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Path mediation analysis reveals GBA impacts Lewy body disease status by increasing α-synuclein levels
2018 · Anna Lisa Gündner, Gonzalo Duran-Pacheco, et al. · Neurobiology of Disease · 69
Purification, Pharmacological Modulation, and Biochemical Characterization of Interactors of Endogenous Human γ-Secretase
2009 · Edith Winkler, Scott Hobson, et al. · Biochemistry · 68
Increase of TREM2 during Aging of an Alzheimer’s Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis
2017 · Matthias Brendel, Gernot Kleinberger, et al. · Frontiers in Aging Neuroscience · 66
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Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [18F]-Florbetaben PET Quantitation in Alzheimer's Model Mice
2016 · Felix Overhoff, Matthias Brendel, et al. · Frontiers in Neuroscience · 66
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Developmental Regulation of Presenilin-1 Processing in the Brain Suggests a Role in Neuronal Differentiation
1997 · Henrike Hartmann, Jorge Busciglio, et al. · Journal of Biological Chemistry · 66
Insensitivity to Aβ42-lowering Nonsteroidal Anti-inflammatory Drugs and γ-Secretase Inhibitors Is Common among Aggressive Presenilin-1 Mutations
2007 · Eva Czirr, Stefanie Leuchtenberger, et al. · Journal of Biological Chemistry · 55
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Cross-Sectional Comparison of Small Animal [18F]-Florbetaben Amyloid-PET between Transgenic AD Mouse Models
2015 · Matthias Brendel, Anna Jaworska, et al. · PLoS ONE · 53
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Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment
2015 · M Brendel, A Jaworska, et al. · Molecular Psychiatry · 50
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Attenuated Aβ42 Responses to Low Potency γ-Secretase Modulators Can Be Overcome for Many Pathogenic Presenilin Mutants by Second-generation Compounds
2011 · Benedikt Kretner, Akio Fukumori, et al. · Journal of Biological Chemistry · 49
Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice
2018 · Carola Focke, Tanja Blume, et al. · Journal of Nuclear Medicine · 48
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Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study
2018 · Tanja Blume, Carola Focke, et al. · Journal of Neuroinflammation · 45
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Central cholinergic functions in human amyloid precursor protein knock-in/presenilin-1 transgenic mice
2004 · J Hartmann, C Erb, et al. · Neuroscience · 41
Works count: 93
Citation count: 4,184
H-index: 31
I10-index: 52
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