Author

Zhi Tan

Observed names: Z. Tan, Zhi Ting Tan

Institution: Australian Red Cross Lifeblood

Observed institutions: The University of Texas MD Anderson Cancer Center, Baylor College of Medicine, Australian Red Cross Lifeblood, Sichuan Entry-Exit Inspection and Quarantine Bureau, Dan L Duncan Comprehensive Cancer Center, Universiti Malaysia Perlis, The University of Texas Health Science Center at Houston, American University of Beirut, Icahn School of Medicine at Mount Sinai

ORCID: 0000-0003-1895-0285

Observed ORCID: 0000-0003-1895-0285

OpenAlex ID: A5074466112

Mechanisms and clinical activity of an EGFR and HER2 exon 20–selective kinase inhibitor in non–small cell lung cancer

2018 · Jacqulyne P. Robichaux, Yasir Y. Elamin, et al. · Nature Medicine · 480

Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth

2016 · Baoli Hu, Qianghu Wang, et al. · Cell · 279

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Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor Microenvironment

2020 · Peiwen Chen, Wen-Hao Hsu, et al. · Cancer Discovery · 228

Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer

2019 · Wantong Yao, Johnathon L. Rose, et al. · Nature · 227

Candidate Antimetastasis Drugs Suppress the Metastatic Capacity of Breast Cancer Cells by Reducing Membrane Fluidity

2016 · Weina Zhao, Sara Prijic, et al. · Cancer Research · 177

Computational polypharmacology: a new paradigm for drug discovery

2017 · Rajan Chaudhari, Zhi Tan, et al. · Expert Opinion on Drug Discovery · 125

An up-to-date overview of computational polypharmacology in modern drug discovery

2020 · Rajan Chaudhari, Long Wolf Fong, et al. · Expert Opinion on Drug Discovery · 86

A noncoding RNA modulator potentiates phenylalanine metabolism in mice

2021 · Yajuan Li, Zhi Tan, et al. · Science · 77

Tumor-associated nonmyelinating Schwann cell–expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion

2023 · Chengcao Sun, Youqiong Ye, et al. · Science Advances · 70

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DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M pro inhibitors

2021 · Srinivas Chamakuri, Shuo Lu, et al. · Proceedings of the National Academy of Sciences · 69

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Hyperphosphorylation of ribosomal protein S6 predicts unfavorable clinical survival in non-small cell lung cancer

2015 · Bojiang Chen, Zhi Tan, et al. · Journal of Experimental & Clinical Cancer Research · 63

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Methylation of HSP70 Orchestrates Its Binding to and Stabilization of BCL2 mRNA and Renders Pancreatic Cancer Cells Resistant to Therapeutics

2020 · Liang Wang, Zhiliang Jia, et al. · Cancer Research · 58

Polypharmacology in Drug Development: A Minireview of Current Technologies

2016 · Zhi Tan, Rajan Chaudhai, et al. · ChemMedChem · 45

Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections

2022 · Ram K. Modukuri, Zhifeng Yu, et al. · Proceedings of the National Academy of Sciences · 44

Reversible male contraception by targeted inhibition of serine/threonine kinase 33

2024 · Angela F. Ku, Kiran L. Sharma, et al. · Science · 40

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Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase Inhibitor

2016 · Zhi Tan, Lu Chen, et al. · Scientific Reports · 38

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Discovery of Highly Potent and BMPR2-Selective Kinase Inhibitors Using DNA-Encoded Chemical Library Screening

2023 · Ram K. Modukuri, Diana Monsivais, et al. · Journal of Medicinal Chemistry · 36

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FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia

2021 · Vaclav Seda, Eva Vojackova, et al. · Blood · 34

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Mechanisms of MCL-1 Protein Stability Induced by MCL-1 Antagonists in B-Cell Malignancies

2022 · Shady I. Tantawy, Aloke Sarkar, et al. · Clinical Cancer Research · 32

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Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology

2024 · Chandrashekhar Madasu, Zian Liao, et al. · Proceedings of the National Academy of Sciences · 22

Past, Present, and Future of Targeting Ras for Cancer Therapies

2015 · Zhi Tan, Shuxing Zhang · Mini-Reviews in Medicinal Chemistry · 21

H19X‐encoded miR‐322(424)/miR‐503 regulates muscle mass by targeting translation initiation factors

2021 · Rui Liang, Xiaopeng Shen, et al. · Journal of Cachexia Sarcopenia and Muscle · 20

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Curation and Analysis of Multitargeting Agents for Polypharmacological Modeling

2014 · A. Srinivas Reddy, Zhi Tan, et al. · Journal of Chemical Information and Modeling · 20

Interaction between nanoparticles and charged phospholipid membranes

2018 · Beibei Huang, Zhi Tan, et al. · Physical Chemistry Chemical Physics · 18

Germline and Somatic Smoothened Mutations in Non–Small-Cell Lung Cancer Are Potentially Responsive to Hedgehog Inhibitor Vismodegib

2017 · Anne S. Tsao, Ignacio Wistuba, et al. · JCO Precision Oncology · 13

Works count: 51

Citation count: 2,381

H-index: 21

I10-index: 27