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Kazuki Hashiba
Institution:
Nitto (Japan)
Observed institutions:
Nitto (Japan),
Hokkaido University
ORCID:
0000-0002-1434-0773
Observed ORCID:
0000-0002-1434-0773
OpenAlex ID:
A5074564949
Understanding structure-activity relationships of pH-sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo
2019
·
Yusuke Sato
, Kazuki Hashiba
, et al.
·
Journal of Controlled Release
·
183
PDF
Different kinetics for the hepatic uptake of lipid nanoparticles between the apolipoprotein E/low density lipoprotein receptor and the N-acetyl-d-galactosamine/asialoglycoprotein receptor pathway
2020
·
Yusuke Sato
, Yoshiyuki Kinami
, et al.
·
Journal of Controlled Release
·
112
Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA
2022
·
Kazuki Hashiba
, Yusuke Sato
, et al.
·
Small Science
·
109
Overcoming thermostability challenges in mRNA–lipid nanoparticle systems with piperidine-based ionizable lipids
2024
·
Kazuki Hashiba
, Masamitsu Taguchi
, et al.
·
Communications Biology
·
95
Hydrophobic scaffolds of pH-sensitive cationic lipids contribute to miscibility with phospholipids and improve the efficiency of delivering short interfering RNA by small-sized lipid nanoparticles
2019
·
Yusuke Sato
, Nana Okabe
, et al.
·
Acta Biomaterialia
·
57
pH-labile PEGylation of siRNA-loaded lipid nanoparticle improves active targeting and gene silencing activity in hepatocytes
2017
·
Kazuki Hashiba
, Yusuke Sato
, et al.
·
Journal of Controlled Release
·
49
PDF
Impact of Lipid Tail Length on the Organ Selectivity of mRNA-Lipid Nanoparticles
2024
·
Kazuki Hashiba
, Masamitsu Taguchi
, et al.
·
Nano Letters
·
40
Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA
2023
·
Kazuki Hashiba
, Yusuke Sato
, et al.
·
Small Science
·
40
PDF
Balancing Multivalent Avidity and Receptor Availability Governs mRNA Delivery by Antibody-Functionalized Lipid Nanoparticles
2026
·
Kazuki Hashiba
, Masahiro Fukasaka
, et al.
·
Nano Letters
·
10
PDF
Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA
2023
·
Kazuki Hashiba
, Yusuke Sato
, et al.
·
Small Science
·
9
PDF
Restricting efferocytosis pathway to CD91 via phosphatidylserine-targeting chimeric protein augments antitumor immune responses
2026
·
Yu Mizote
, Hiroki Nishita
, et al.
·
Molecular Therapy
·
1
Optimized Chemical Modifications Enhance Lipid Nanoparticle-Mediated siRNA Silencing of YAP1 and WWTR1
2026
·
Kaito Ueda
, Tatsuki Sato
, et al.
·
Nucleic Acid Therapeutics
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Works count:
12
Citation count:
705
H-index:
9
I10-index:
9
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